Comparative evaluation of enzyme-linked immunosorbent assays based on crude and recombinant leishmanial antigens for serodiagnosis of symptomatic and asymptomatic Leishmania infantum visceral infections in dogs

Clinical and Vaccine Immunology

Volumn 14, Issue 5, 2007, Pages 544-548

  Porrozzi, Renato ^a   Santos Da Costa, Marcos V ^a   Teva, Antonio ^a   Falqueto, Aloísio ^b   Ferreira, Adelson L ^b   Dos Santos, Claudiney D ^b   Fernandes, Ana Paula ^c   Gazzinelli, Ricardo T ^a,c   Campos Neto, Antonio ^d   Grimaldi Jr , Gabriel ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF ESPÍRITO SANTO   (Brazil)

^c FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^d FORSYTH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD GROUP A2 ANTIGEN; IMMUNOGLOBULIN G; K26 ANTIGEN; K39 ANTIGEN; PROTOZOAL PROTEIN; PROTOZOON ANTIBODY; RECOMBINANT ANTIGEN; UNCLASSIFIED DRUG; A2 PROTEIN, LEISHMANIA DONOVANI; K26 ANTIGEN, LEISHMANIA CHAGASI; K39 ANTIGEN, LEISHMANIA; PARASITE ANTIGEN;

ANIMAL EXPERIMENT; ANTIBODY DETECTION; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CONTROLLED STUDY; CROSS REACTION; DOG; ENZYME LINKED IMMUNOSORBENT ASSAY; LEISHMANIA INFANTUM; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SERODIAGNOSIS; SEROLOGY; VISCERAL LEISHMANIASIS; ANIMAL; ANIMAL DISEASE; BLOOD; CLINICAL TRIAL; COMPARATIVE STUDY; IMMUNOLOGY; LEISHMANIA DONOVANI; METHODOLOGY; REPRODUCIBILITY;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; DOGS; ENZYME-LINKED IMMUNOSORBENT ASSAY; LEISHMANIA DONOVANI; LEISHMANIA INFANTUM; LEISHMANIASIS, VISCERAL; PROTOZOAN PROTEINS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 34250340086     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00420-06     Document Type: Article

References (34)

1. Abranches, P., G. Santos-Gomes, N. Rachamim, L. Campino, L. F. Schnur, and C. L. Jaffe. 1991. An experimental model for canine visceral leishmaniasis. Parasite Immunol. 13:537-550.
2. Aisa, M. J., S. Castillejo, M. Gallego, R. Fisa, M. C. Riera, M. De Colmenares, S. Torras, X. Roura, J. Sentis, and M. Portus. 1998. Diagnostic potential of Western blot analysis of sera from dogs with leishmaniasis in endemic areas and significance of the pattern. Am. J. Trop. Med. Hyg. 58:154-159.
3. Badaró, R., D. Benson, M. C. Eulálio, M. Freire, S. Cunha, E. M. Neto, D. Pedral-Sampaio, C. Madureira, J. M. Burns, R. L. Houghton, J. R. David, and S. G. Reed. 1996. rK39: a cloned antigen of Leishmania chagasi that predicts active visceral leishmaniasis. J. Infect. Dis. 173:758-761.
4. Badaró, R., M. C. Eulálio, D. Benson, M. Freire, J. C. Miranda, D. Pedral-Sampaio, J. M. Burns, J. R. David, Jr., W. J. Johnson, and S. G. Reed. 1993. Sensitivity and specificity of a recombinant Leishmania chagasi antigen in the serodiagnosis of visceral leishmaniasis. Arch. Inst. Pasteur (Tunis) 70:331-332.
5. Bhatia, A., N. S. Daifalla, S. Jen, R. Badaro, S. G. Reed, and Y. A. Skeike. 1999. Cloning, characterization and serological evaluation of K9 and K26: two related hydrophilic antigens of Leishmania chagasi. Mol. Biochem. Parasitol. 102:249-261.
6. Boarino, A., A. Scalone, L. Gradoni, E. Ferroglio, F. Vitale, R. Zanatta, M. G. Giuffrida, and S. Rasati. 2005. Development of recombinant chimeric antigen expressing immunodominant B epitopes of Leishmania infantum for serodiagnosis of visceral leishmaniasis. Clin. Diagn. Lab. Immunol. 12:647-653.
7. Boelaert, M., S. Rijal, S. Regmi, R. Singh, B. Karki, D. Jacquet, F. Chappuis, L. Campino, P. Desjeux, D. Le Ray, S. Koirala, and P. Van der Stuyft. 2004. A comparative study of the effectiveness of diagnostic tests for visceral leishmaniasis. Am. J. Trop. Med. Hyg. 70:72-77.
8. Braga, M. D., I. C. Coelho, M. M. Pompeu, T. G. Evans, I. T. MacAullife, M. J. Teixeira, and J. W. Lima. 1998. Control of canine visceral leishmaniasis: comparison of results from a rapid elimination program of serumreactive dogs using an immunoenzyme assay and slower elimination of serum-reactive dogs using filter paper elution indirect immunofluorescence. Rev. Soc. Bras. Med. Trop. 31:419-424.
9. Burns, J. M., Jr., W. G. Shreffler, D. R. Benson, H. W. Ghalib, R. Badaro, and S. G. Reed. 1993. Molecular characterization of a kinesin-related antigen of Leishmania chagasi that detects specific antibody in African and American visceral leishmaniasis. Proc. Natl. Acad. Sci. USA 90:775-779.
10. Carvalho, F. A. A., H. Charest, C. A. P. Tavares, G. Matlashewski, E. P. Valente, A. Rabello, R. T. Gazinelli, and A. P. Fernández. 2002. Diagnosis of American visceral leishmaniasis in humans and dogs using the recombinant Leishmania donovani A2 antigen. Diagn. Microbiol. Infect. Dis. 43:289-295.
11. Courtenay, O., R. J. Quinnell, L. M. Garcez, J. J. Shaw, and C. Dye. 2002. Infectiousness in a cohort of Brazilian dogs: why culling fails to control visceral leishmaniasis in areas of high transmission. J. Infect. Dis. 186:1314-1320.
12. Cupolillo, E., L. R. Brahim, C. B. Toaldo, M. P. Oliveira-Neto, M. E. Felinto de Brito, A. Falqueto, M. F. Naiff, and G. Grimaldi, Jr. 2003. Genetic polymorphism and molecular epidemiology of Leishmania (Viannia) braziliensis from different hosts and geographic areas in Brazil. J. Clin. Microbiol. 41:3126-3132.
13. Delgado, O., M. D. Feliciangeli, V. Coraspe, S. Silva, A. Perez, and J. Arias. 2001. Value of a dipstick based on recombinant rK39 antigen for differential diagnosis of American visceral leishmaniasis from other sympatric endemic diseases in Venezuela. Parasite 8:355-357.
14. Desplazes, P., N. C. Smith, P. Arnold, H. Lutz, and J. Eckert. 1995. Specific IgG1 and IgG2 antibody responses of dogs to Leishmania infantum and other parasites. Parasite Immunol. 17:451-458.
15. Dye, C., R. Killick-Kendrick, M. M. Vitutia, R. Walton, M. Killick-Kendrick, A. E. Harith, M. W. Guy, M.-C. Cañavate, and G. Hasibeder. 1992. Epidemiology of canine leishmaniasis: prevalence, incidence and basic reproduction number calculated from a cross-sectional serological survey on the island of Gozo, Malta. Parasitology 105:35-41.
16. Dye, C., E. Vidor, and J. Deneure. 1993. Serological diagnosis of leishmaniasis: on detecting infection as well as disease. Epidemiol. Infect. 103:647-656.
17. Ghedin, E., W. W. Zhang, H. Charest, S. Sundar, R. T. Kenney, and G. Matlashewski. 1997. Antibody response against Leishmania donovani amastigote-stage-specific protein in patients with visceral leishmaniasis. Clin. Diagn. Lab. Immunol. 4:530-535.
18. Grimaldi, G., Jr., and R. B. Tesh. 1993. Leishmaniasis of the New World: current concepts and implications for future research. Clin. Microbiol. Rev. 6:230-250.
19. Harith, A., A. H. Kolk, P. A. Kager, J. Leeuwenburg, R. Muigai, S. Kiugu, and J. J. Laarman. 1986. A simple and economical direct agglutination test for serodiagnosis and sero-epidemiological studies of visceral leishmaniasis. Trans. R. Soc. Trop. Med. Hyg. 80:583-587.
20. Mancianti, F., and N. Meciani. 1988. Specific serodiagnosis of canine leishmaniasis by indirect immunofluorescence, indirect hemagglutination, and counter-immunoelectrophoresis. Am. J. Vet. Res. 49:1409-1411.
21. Mettler, M., F. Grimm, G. Capelli, and H. Camp. 2005. Evaluation of enzyme-linked immunosorbent assays, an immunofluorescent-antibody test, and two rapid tests (immunochromatographic-dipstick and gel tests) for serological diagnosis of symptomatic and asymptomatic Leishmania infections in dogs. J. Clin. Microbiol. 43:5515-5519.
22. Otranto, D., P. Paradies, M. Sasanelli, R. Spinelli, and O. Brandonisio. 2004. Rapid immunochromatographic test for serodiagnosis of canine leishmaniasis. J. Clin. Microbiol. 42:2769-2770.
23. Quinnell, R. J., O. Courtenay, S. Davidson, L. Garcez, B. Lambson, P. Ramos, J. J. Shaw, M. A. Shaw, and C. Dye. 2001. Detection of Leishmania infantum by PCR, serology and immune response in a cohort study of Brazilian dogs. Parasitology 122:253-261.
24. Quinnell, R. J., O. Courtenay, L. Garcez, and C. Dye. 1997. The epidemiology of canine leishmaniasis: transmission rates estimated from a cohort study in Amazonian Brazil. Parasitology 115:143-156.
25. Reithinger, R., R. J. Quinnell, B. Alexander, and C. R. Davies. 2002. Rapid detection of Leishmania infantum infection in dogs: comparative study using an immunochromatographic dipstick test, enzyme-linked immunosorbent assay, and PCR. J. Clin. Microbiol. 40:2352-2356.
26. Rhalem, A., H. Sahibi, N. Gueeous-Idrissi, S. Lasri, A. Natami, M. Riyad, and B. Berrag. 1999. Immune response against Leishmania antigens in dogs naturally and experimentally infected with Leishmania infantum. Vet. Parasitol. 81:173-184.
27. Rosario, E. Y., O. Genaro, J. C. França-Silva, and R. T. Da Costa. 2005. Evaluation of enzyme-linked immunosorbent assay using crude Leishmania and recombinant antigens as a diagnostic marker for canine visceral leishmaniasis. Mem. Inst. Oswaldo Cruz 100:197-203.
28. Scalone, A., R. De Luna, G. Oliva, L. Balde, G. Satta, G. Vesco, W. Mignone, C. Turilli, R. R. Mondesire, D. Simpson, A. R. Donoghue, G. R. Frank, and L. Gradoni. 2002. Evaluation of the Leishmania recombinant K39 antigen as a diagnostic marker for canine leishmaniasis and validation of a standardized enzyme-linked immunosorbent assay. Vet. Parasitol. 104:275-285.
29. Solano-Gallego, L., C. Riera, X. Roura, L. Iniesta, M. Gallego, J. E. Valladares, R. Fisa, S. Castiççejo, J. Alberola, L. Ferrer, M. Arboix, and M. Portús. 2001. Leishmania infantum-specific IgG, IgG1 and IgG2 antibody responses in healthy and ill dogs from endemic areas. Evolution in the course of infection and after treatment. Vet. Parasitol. 96:265-276.
30. Soto, M., J. M. Requena, L. Quijada, and C. Alonso. 1998. Multicomponent chimeric antigen for serodiagnosis of canine visceral leishmaniasis. J. Clin. Microbiol. 36:58-63.
31. Teodoro da Costa, R., J. C. França, W. Mayrink, E. Nascimento, O. Genaro, and A. Campos-Neto. 2003. Standardization of a rapid immunochromatographic test with the recombinant antigens K39 and K26 for the diagnosis of canine visceral leishmaniasis. Trans. R. Soc. Trop. Med. Hyg. 97:678-682.
32. Vercammen, F., D. Berkvens, J. Brandt, and W. Vansteenkiste. 1998. A sensitive and specific 30-min Dot-ELISA for the detection of anti-leishmania antibodies in the dog. Vet. Parasitol. 79:221-228.
33. Zijlstra, E. E., M. S. Ali, A. M. El Hassan, I. A. El Toum, M. Satti, H. W. Ghalib, and P. A. Kager. 1992. Kala-azar: a comparative study of parasitological methods and the direct agglutination test in diagnosis. Trans. R. Soc. Trop. Med. Hyg. 86:505-507.
34. Zijlstra, E. E., N. S. Daifalla, P. A. Pager, E. A. Khalil, A. M. El-Hassan, S. G. Reed, and H. W. Ghalib. 1998. rK39 enzyme-linked immunosorbent assay for diagnosis of Leishmania donovani infection. Clin. Diagn. Lab. Immunol. 5:717-720.