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Volumn 21, Issue 6, 2007, Pages 523-530

Phytopreventative effects of Gynostemma pentaphyllum against acute indomethacin-induced gastrointestinal and renal toxicity in rats

Author keywords

Gastrointestinal; Gynostemma pentaphyllum; Gypenosides; Renal; Toxicity; Ulcer

Indexed keywords

GYPENOSIDE; HEMOGLOBIN; INDOMETACIN; LACTOSE; N ACETYL BETA GLUCOSAMINIDASE; PLANT EXTRACT;

EID: 34250321213     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2086     Document Type: Article
Times cited : (10)

References (24)
  • 1
    • 0041663626 scopus 로고    scopus 로고
    • Gypenosides derived from Gynostemma pentaphyllum suppress NO synthesis in murine macrophages by inhibiting iNOS enzymatic activity and attenuating NF-kappaB-mediated iNOS protein expression
    • Aktan F, Henness S, Roufogalis BD, Ammit AJ. 2003. Gypenosides derived from Gynostemma pentaphyllum suppress NO synthesis in murine macrophages by inhibiting iNOS enzymatic activity and attenuating NF-kappaB-mediated iNOS protein expression. Nitric Oxide 8: 235-242.
    • (2003) Nitric Oxide , vol.8 , pp. 235-242
    • Aktan, F.1    Henness, S.2    Roufogalis, B.D.3    Ammit, A.J.4
  • 2
    • 34250359983 scopus 로고    scopus 로고
    • Chiang Su New Medicinal College. 1977. Dictionary of Chinese Crude Drugs. Shanghai Scientific Technologic Publisher: Shanghai, 16.
    • Chiang Su New Medicinal College. 1977. Dictionary of Chinese Crude Drugs. Shanghai Scientific Technologic Publisher: Shanghai, 16.
  • 3
    • 18544373768 scopus 로고
    • China Pharmaceutical University, 1st edn, Yan Y-Q chief ed, China Medicine, Science and Technology Publisher: China, 1996
    • China Pharmaceutical University. 1996. In Encyclopedia of Chinese Herbs Vol 2, 1st edn, Yan Y-Q (chief ed.). China Medicine, Science and Technology Publisher: China, 1878-1882.
    • (1878) Encyclopedia of Chinese Herbs , vol.2
  • 4
    • 1642325127 scopus 로고    scopus 로고
    • Effectiveness of Harpagophytum extracts and clinical efficacy
    • Chrubasik S, Conradt C, Roufogalis BD. 2004. Effectiveness of Harpagophytum extracts and clinical efficacy. Phytother Res 18: 187-189.
    • (2004) Phytother Res , vol.18 , pp. 187-189
    • Chrubasik, S.1    Conradt, C.2    Roufogalis, B.D.3
  • 5
    • 0033153773 scopus 로고    scopus 로고
    • Gynostemma pentaphyllum: Identification of major sapogenins and differentiation from Panax species
    • Cui JF, Eneroth P, Bruhn JG. 1999. Gynostemma pentaphyllum: identification of major sapogenins and differentiation from Panax species. Eur J Pharm Sci 8: 187-191.
    • (1999) Eur J Pharm Sci , vol.8 , pp. 187-191
    • Cui, J.F.1    Eneroth, P.2    Bruhn, J.G.3
  • 6
    • 0031953319 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drug-induced gastrointestinal permeability
    • Davies NM. 1998. Non-steroidal anti-inflammatory drug-induced gastrointestinal permeability. Aliment Pharm Ther 12: 303-320.
    • (1998) Aliment Pharm Ther , vol.12 , pp. 303-320
    • Davies, N.M.1
  • 7
    • 16244365087 scopus 로고    scopus 로고
    • COX-2 selective inhibitors cardiac toxicity: Getting to the heart of the matter
    • Davies NM, Jamali F. 2004. COX-2 selective inhibitors cardiac toxicity: getting to the heart of the matter. J Pharm Pharm Sci 7: 332-336.
    • (2004) J Pharm Pharm Sci , vol.7 , pp. 332-336
    • Davies, N.M.1    Jamali, F.2
  • 8
    • 0030022530 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drug-induced enteropathy and severe chronic anemia in a patient with rheumatoid arthritis
    • Davies NM, Jamali F, Skeith KJ. 1996. Nonsteroidal antiinflammatory drug-induced enteropathy and severe chronic anemia in a patient with rheumatoid arthritis. Arth Rheum 39: 321-324.
    • (1996) Arth Rheum , vol.39 , pp. 321-324
    • Davies, N.M.1    Jamali, F.2    Skeith, K.J.3
  • 9
    • 0034020103 scopus 로고    scopus 로고
    • Choosing the right nonsteroidal anti-inflammatory drug for the right patient: A pharmaco-kinetic approach
    • Davies NM, Skjodt NM. 2000. Choosing the right nonsteroidal anti-inflammatory drug for the right patient: a pharmaco-kinetic approach. Clin Pharmacokinet 38: 377-392.
    • (2000) Clin Pharmacokinet , vol.38 , pp. 377-392
    • Davies, N.M.1    Skjodt, N.M.2
  • 10
    • 0348037594 scopus 로고    scopus 로고
    • Gastrointestinal toxicity, antiinflammatory activity, and superoxide dismutase activity of copper and zinc complexes of the antiinflammatory drug indomethacin
    • Dillon CT, Hambley TW, Kennedy BJ et al. 2003. Gastrointestinal toxicity, antiinflammatory activity, and superoxide dismutase activity of copper and zinc complexes of the antiinflammatory drug indomethacin. Chem Res Toxicol 16: 28-37.
    • (2003) Chem Res Toxicol , vol.16 , pp. 28-37
    • Dillon, C.T.1    Hambley, T.W.2    Kennedy, B.J.3
  • 11
    • 0037423022 scopus 로고    scopus 로고
    • Role of bacteria and inducible nitric oxide synthase activity in the systemic inflammatory microvascular response provoked by indomethacin in the rat
    • Evans SM, Whittle BJ. 2003. Role of bacteria and inducible nitric oxide synthase activity in the systemic inflammatory microvascular response provoked by indomethacin in the rat. Eur J Pharmacol 461: 63-71.
    • (2003) Eur J Pharmacol , vol.461 , pp. 63-71
    • Evans, S.M.1    Whittle, B.J.2
  • 12
    • 0035182040 scopus 로고    scopus 로고
    • Effects of Lactobacillus ingestion on the gastrointestinal mucosal barrier alterations induced by indomethacin in humans
    • Gotteland M, Cruchet S, Verbeke S. 2001. Effects of Lactobacillus ingestion on the gastrointestinal mucosal barrier alterations induced by indomethacin in humans. Aliment Pharm Ther 15: 11-17.
    • (2001) Aliment Pharm Ther , vol.15 , pp. 11-17
    • Gotteland, M.1    Cruchet, S.2    Verbeke, S.3
  • 14
    • 33745684789 scopus 로고    scopus 로고
    • Gypenoside XLIX isolated from Gynostemma pentaphyllum inhibits nuclear factor-kappaB activation via PPAR-α-dependent pathway
    • Huang TH-W, Li Y, Razmovski-Naumovski V et al. 2006. Gypenoside XLIX isolated from Gynostemma pentaphyllum inhibits nuclear factor-kappaB activation via PPAR-α-dependent pathway. J Biomed Sci 13: 535-548.
    • (2006) J Biomed Sci , vol.13 , pp. 535-548
    • Huang, T.H.-W.1    Li, Y.2    Razmovski-Naumovski, V.3
  • 15
    • 0003735760 scopus 로고
    • National Research Institute of Chinese Medicine: Taipei
    • Kan WS. 1975. Pharmaceutical Botany. National Research Institute of Chinese Medicine: Taipei, 539-540.
    • (1975) Pharmaceutical Botany , pp. 539-540
    • Kan, W.S.1
  • 16
    • 0027351284 scopus 로고
    • Evaluation of the anti-inflammatory and liver-protective effects of Anoecfo chilus formosanus, Ganoderma lucidum and Gynostemma pentaphyllum in rats
    • Lin JM, Lin CC, Chiu HF, Yang JJ, Lee SG. 1993. Evaluation of the anti-inflammatory and liver-protective effects of Anoecfo chilus formosanus, Ganoderma lucidum and Gynostemma pentaphyllum in rats. Am J Chin Med 21: 59-69.
    • (1993) Am J Chin Med , vol.21 , pp. 59-69
    • Lin, J.M.1    Lin, C.C.2    Chiu, H.F.3    Yang, J.J.4    Lee, S.G.5
  • 17
    • 27444432789 scopus 로고    scopus 로고
    • Phytopreventative anti-hyperlipidemic effects of Gynostemma pentaphyllum in rats
    • Megalli S, Aktan F, Davies NM, Roufogalis BD. 2005. Phytopreventative anti-hyperlipidemic effects of Gynostemma pentaphyllum in rats. J Pharm Pharm Sci 8: 507-515.
    • (2005) J Pharm Pharm Sci , vol.8 , pp. 507-515
    • Megalli, S.1    Aktan, F.2    Davies, N.M.3    Roufogalis, B.D.4
  • 18
    • 0031014088 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drug enteropathy in rats: Role of permeability, bacteria, and enterohepatic circulation
    • Reuter BK, Davies NM, Wallace JL. 1997. Nonsteroidal antiinflammatory drug enteropathy in rats: role of permeability, bacteria, and enterohepatic circulation. Gastroenterology 112: 109-117.
    • (1997) Gastroenterology , vol.112 , pp. 109-117
    • Reuter, B.K.1    Davies, N.M.2    Wallace, J.L.3
  • 19
    • 3242753426 scopus 로고    scopus 로고
    • The anti-gastric ulcer effect of Gynostemma pentaphyllum Makino
    • Rujjanawate C, Kanjanapothi D, Amornlerdpison D. 2004. The anti-gastric ulcer effect of Gynostemma pentaphyllum Makino. Phytomedicine 11: 431-435.
    • (2004) Phytomedicine , vol.11 , pp. 431-435
    • Rujjanawate, C.1    Kanjanapothi, D.2    Amornlerdpison, D.3
  • 20
    • 0141541775 scopus 로고    scopus 로고
    • Formulation dependent pharmacokinetics, bioavailability and renal toxicity of a selective cyclooxygenase-1 inhibitor SC-560 in the rat
    • Teng XW, Abu-Mellal AK, Davies NM. 2003. Formulation dependent pharmacokinetics, bioavailability and renal toxicity of a selective cyclooxygenase-1 inhibitor SC-560 in the rat. J Pharm Pharm Sci 6: 205-210.
    • (2003) J Pharm Pharm Sci , vol.6 , pp. 205-210
    • Teng, X.W.1    Abu-Mellal, A.K.2    Davies, N.M.3
  • 21
    • 0030746173 scopus 로고    scopus 로고
    • N-Acetyl-beta-D-glucosaminidase urinary excretion as an early indicator of kidney dysfunction in rheumatoid arthritis patients on low-dose methotrexate treatment
    • Wiland P, Swierkot J. 1997. N-Acetyl-beta-D-glucosaminidase urinary excretion as an early indicator of kidney dysfunction in rheumatoid arthritis patients on low-dose methotrexate treatment. Br J Rheumatol 36: 7-9; 59-63.
    • (1997) Br J Rheumatol , vol.36
    • Wiland, P.1    Swierkot, J.2
  • 22
    • 0031172681 scopus 로고    scopus 로고
    • Toxicokinetics of indomethacin-induced intestinal permeability in the rat
    • Wright MR, Davies NM, Jamali F. 1997. Toxicokinetics of indomethacin-induced intestinal permeability in the rat. Pharmacol Res 35: 499-504.
    • (1997) Pharmacol Res , vol.35 , pp. 499-504
    • Wright, M.R.1    Davies, N.M.2    Jamali, F.3
  • 23
    • 84986517562 scopus 로고
    • HPTLC fingerprint identification of commercial ginseng drugs - reinvestigation of HPTLC of ginsenosides
    • Xie PS, Yan YZ. 1987. HPTLC fingerprint identification of commercial ginseng drugs - reinvestigation of HPTLC of ginsenosides. J High Resolut Chromatogr and Chromatogr Commun 10: 607-613.
    • (1987) J High Resolut Chromatogr and Chromatogr Commun , vol.10 , pp. 607-613
    • Xie, P.S.1    Yan, Y.Z.2
  • 24
    • 0032887039 scopus 로고    scopus 로고
    • Therapeutic role and its mechanism of gypenosides on delayed healing of experimental gastric ulcer induced by NCTC11637 strain HP in rats
    • Zhang Q-B, Ma J-J, Chao Z-X, Lin Z-B. 1999. Therapeutic role and its mechanism of gypenosides on delayed healing of experimental gastric ulcer induced by NCTC11637 strain HP in rats. Chin Pharmacol Bull 15: 225-228.
    • (1999) Chin Pharmacol Bull , vol.15 , pp. 225-228
    • Zhang, Q.-B.1    Ma, J.-J.2    Chao, Z.-X.3    Lin, Z.-B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.