Microphotonic control of single molecule fluorescence correlation spectroscopy using planar optofluidics

Optics Express

Volumn 15, Issue 12, 2007, Pages 7290-7295

  Yin, D ^a   Lunt, E J ^b   Barman, A ^a,c   Hawkins, A R ^b   Schmidt, H ^a  

^a University of California Santa Cruz   (United States)

^b Department of Electrical and Computer Engineering   (United States)

^c INDIAN INSTITUTE OF TECHNOLOGY DELHI   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOCORRELATION; DYES; FLUORESCENCE SPECTROSCOPY; LITHOGRAPHY; OPTICAL WAVEGUIDES; PHOTONICS;

AUTOCORRELATION FUNCTION; FLUORESCENCE CORRELATION SPECTROSCOPY (FCS); MICROPHOTONIC CONTROL; OPTOFLUIDICS;

MICROPROCESSOR CHIPS;

EID: 34250218225     PISSN: None     EISSN: 10944087     Source Type: Journal    
DOI: 10.1364/OE.15.007290     Document Type: Article

References (18)

1. C. Zander, J. Enderlein, and R.A. Keller, "Single-molecule detection in solution: methods and applications," 1st ed., Wiley (2002).
2. E. B. Shera, N. K. Seitzinger, L. M. Davis, R. A. Keller and S. A. Soper, "Detection of single fluorescent molecules," Chem. Phys. Lett. 174, 553 (1990).
3. W.E. Moerner and D.P. Fromm, "Methods of single-molecule fluorescence spectroscopy and microscopy," Rev. Sci. Instrum. 74, 3597 (2003).
4. S. Kuhn, U. Hakanson, L. Rogobete, and V. Sandoghdar, "Enhancement of single-molecule fluorescence using a gold nanoparticle as an optical nanoantenna," Phys. Rev. Lett., 97, 017402 (2006).
5. D. Magde, E. Elson, and W.W. Webb, "Thermodynamic Fluctuations in a Reacting System-Measurement by Fluorescence Correlation Spectroscopy," Phys. Rev. Lett., 29, 705 (1972).
6. M. Brinkmeier, K. Dorre, K. Riebeseel, and R. Rigler, "Confocal spectroscopy in microstructures," Biophys. Chem. 66, 229 (1997).
7. M. Foquet, J. Korlach, W. R. Zipfel, W.W.Webb and H. G. Craighead, "DNA Fragment Sizing by Single Molecule Detection in Submicrometer-Sized Closed Fluidic Channels," Anal. Chem. 74, 1415-1422 (2002).
8. M. Foquet, J. Korlach, W. R. Zipfel, W.W.Webb and H. G. Craighead, "Focal Volume Confinement by Submicrometer-Sized Fluidic Channels," Anal. Chem. 76, 1618-1626 (2004).
9. L. Kastrup, H. Blom, C. Eggeling, S.W. Hell, "Fluorescence fluctuation spectroscopy in subdiffraction focal volumes," Phys. Rev. Lett., 94, 178104 (2005).
10. C. Monat, P. Domachuk and B.J. Eggleton, "Integrated optofluidics: A new river of light," Nat. Photonics, 1, 106 (2007).
11. D. Yin, J.P. Barber, A.R. Hawkins, D.W. Deamer, H. Schmidt, "Integrated optical waveguides with liquid cores," Appl. Phys. Lett., 85, 3477 (2004).
12. D. Yin, J.P. Barber, D.W. Deamer, A.R. Hawkins, H. Schmidt, "Single-molecule detection sensitivity using planar integrated optics on a chip," Opt. Lett. 31, 2136 (2006).
13. H. Schmidt, D. Yin, J.P. Barber, and A.R. Hawkins, "Hollow-core waveguides and 2D waveguide arrays for integrated optics of gases and liquids," IEEE J. Sel. Top. in Quantum. Electron. 11, 519 (2005).
14. J.P. Barber, E.J. Lunt, Z. George, D. Yin, H. Schmidt, and A.R. Hawkins, "Integrated Hollow Waveguides with Arch-shaped Cores," IEEE Photon. Technol. Lett., 18, 28 (2006).
15. D. Yin, J.P. Barber, A.R. Hawkins, and H. Schmidt, "Highly efficient fluorescence detection in picoliter volume liquid-core waveguides," Applied Physics Letters, 87, 211111 (2005).
16. P.F. Lenne, E. Etienne, and H. Rigneault, "Subwavelength patterns and high detection efficiency in fluorescence correlation spectroscopy using photonic structures," Appl. Phys. Lett. 80, 4106 (2002).
17. P. Schwille, U. Haupts, S. Maiti, W.W. Webb, "Molecular Dynamics in Living Cells Observed by Fluorescence Correlation Spectroscopy with 1- and 2-Photon Excitation," Biophys. J., 77, 2251 (1999).
18. M. Eigen and R. Rigler, "Sorting Single Molecules: Application to Diagnostics and Evolutionary Biotechnology," PNAS 91, 5740 (1994).