Oligonucleotides containing 6-Aza-2′-deoxyuridine: Synthesis, nucleobase protection, pH-dependent duplex stability, and metal-DNA formation

Journal of Organic Chemistry

Volumn 72, Issue 12, 2007, Pages 4358-4366

  Seela, Frank ^a   Chittepu, Padmaja ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYURIDINE; NUCLEOBASE PROTECTION; NUCLEOSIDES; SOLID PHASE SYNTHESIS;

CONFORMATIONS; DEPROTONATION; DNA; OLIGONUCLEOTIDES; SINGLE CRYSTALS; SYNTHESIS (CHEMICAL);

ORGANIC COMPOUNDS;

2 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL) N 4 (2 METHOXYBENZOYL) 1,2,4 TRIAZIN 3,5(2H,4H) DIONE; 2 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL) N 4 (2,4 DIMETHOXYBENZOYL) 1,2,4 TRIAZIN 3,5(2H,4H) DIONE; 2 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL) N 4 BENZOYL 1,2,4 TRIAZIN 3,5(2H,4H) DIONE; 2 [2 DEOXY 5 O (4,4' DIMETHOXYTRITYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] 1,2,4 TRIAZIN 3,5(2H,4H) DIONE; 2 [2 DEOXY 5 O (4,4' DIMETHOXYTRITYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] N 4 (2 METHOXYBENZOYL) 1,2,4 TRIAZIN 3,5(2H,4H) DIONE; 2 [2 DEOXY 5 O (4,4' DIMETHOXYTRITYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] N 4 (2 METHOXYBENZOYL) 1,2,4 TRIAZIN 3,5(2H,4H) DIONE 3' (2 CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE; 6 AZA 2' DEOXYURIDINE; DEOXYURIDINE; METAL; MONOMER; NUCLEIC ACID BASE; OLIGONUCLEOTIDE; PHOSPHORAMIDITE 2; PHOSPHORAMIDITE 3; PHSOPHORAMIDITE 1; UNCLASSIFIED DRUG; ZINC ION;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONFORMATION; PH MEASUREMENT; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; SOLID PHASE SYNTHESIS; X RAY CRYSTALLOGRAPHY;

DEOXYURIDINE; DNA; DRUG STABILITY; HYDROGEN-ION CONCENTRATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; NUCLEOSIDES; OLIGODEOXYRIBONUCLEOTIDES; ORGANOPHOSPHORUS COMPOUNDS; ZINC;

EID: 34250195337     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0702903     Document Type: Article

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