Effect of castration on male rabbit lower urinary tract tissue enzymes

Molecular and Cellular Biochemistry

Volumn 301, Issue 1-2, 2007, Pages 227-233

  Juan, Yung Shun ^d   Onal, Bulent ^e   Broadaway, Samuel ^b   Cosgrove, Julia ^b   Leggett, Robert E ^a,b   Whitbeck, Catherine ^a   De, Elise ^c   Sokol, Rebekah ^f   Levin, Robert M ^a,b,c  

^a STRATTON VA MEDICAL CENTER   (United States)

^b ALBANY COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

^c ALBANY MEDICAL COLLEGE   (United States)

^d KAOHSIUNG MUNICIPAL HSIAO KANG HOSPITAL   (Taiwan)

^e ISTANBUL UNIVERSITY   (Turkey)

^f Albany Academy for Girls   (United States)

Author keywords

Atpase; Bladder; Castration; Choline acetyl transferase; Mitochondria; Rabbit

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ANDROGEN; CHOLINE ACETYLTRANSFERASE; CITRATE SYNTHASE; LIQUID NITROGEN; SARCOENDOPLASMIC RETICULUM CALCIUM ATPASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLADDER MUCOSA; BLADDER WALL; CALCIUM METABOLISM; CALCIUM TRANSPORT; CASTRATION; CHOLINERGIC NERVE; CONTROLLED STUDY; CORPUS CAVERNOSUM; CRYOPRESERVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; ISOLATION PROCEDURE; MALE; METABOLISM; MITOCHONDRION; NERVE FUNCTION; NONHUMAN; RABBIT; SARCOPLASMIC RETICULUM; TISSUE SECTION; URETHRA; URINARY TRACT FUNCTION;

ANIMALS; CALCIUM-TRANSPORTING ATPASES; CASTRATION; CHOLINE O-ACETYLTRANSFERASE; CITRATE (SI)-SYNTHASE; HUMANS; MALE; MUSCLE, SMOOTH; ORGAN SIZE; PROSTATIC HYPERPLASIA; RABBITS; TESTOSTERONE; URINARY TRACT;

ORYCTOLAGUS CUNICULUS;

EID: 34250187118     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-007-9415-8     Document Type: Article

References (23)

1. Buttyan R, Chen MW, Levin RM (1997) Animal models of bladder outlet obstruction and molecular insights into the basis for the development of bladder dysfunction. Eur Urol 32(Suppl 1):32-39
2. Mostwin JL, Karim OM, van Koeveringe G, Brooks EL (1991) The guinea pig as a model of gradual urethral obstruction. J Urol 145:854-858
3. Levin RM, Chichester P, Hass MA, Gosling JA, Buttyan R (2002) Obstructive bladder dysfunction: Morphological, biochemical, and molecular changes. Eur Urol Suppl 1:14-20
4. Salmi S, Santti R, Gustafsson JA, Makela S (2001) Co-localization of androgen receptor with estrogen receptor beta in the lower urinary tract of the male rat. J Urol 166:674-677
5. Haugaard N, Potter L, Wein AJ, Levin RM (1992) Effect of partial obstruction of the rabbit urinary bladder on malate dehydrogenase and citrate synthase activity. J Urol 147:1391-1393
6. Levin RM, Nicholas TJ, Snitkoff GG, Mandell J, Russell D, Wilbur HJ, Mogavero LJ (1997) Subcellular distribution of SERCA and calcium activated ATPase in rabbit and human urinary bladder smooth muscle. Pharmacology 55:136-143
7. Levin RM, Saito M, Wein AJ, Packard D, Cohen A, Haugaard M (1993) Effect of partial outlet obstruction on choline acetyltransferase activity in the rat and rabbit. Neurourol Urodyn 12:255-262
8. Stas SN, Anastasiadis AG, Fisch H, Benson MC, Shabsigh R (2003) Urologic aspects of andropause. Urology 61:261-266
9. Sajjad Y, Quenby S, Nickson P, Lewis-Jones DI, Vince G (2004) Immuno-histochemical localization of androgen receptors in the urogenital tracts of human embryos. Reproduction: 128:331-339
10. Traish AM, Toselli P, Jeong SJ, Kim NN (2005) Adipocyte accumulation in penile corpus cavernosum of the orchiectomized rabbit: A potential mechanism for veno-occlusive dysfunction in androgen deficiency. J Androl 26:242-248
11. Swerdloff RS, Wang C (1993) Androgen deficiency and aging in men. West J Med 159:579-585
12. Keast JR, Saunders RJ (1998) Testosterone has potent, selective effects on the morphology of pelvic autonomic neurons which control the bladder, lower bowel and internal reproductive organs of the male rat. Neuroscience 85:543-556
13. Hall R, Andrews PL, Hoyle CH (2002) Effects of testosterone on neuromuscular transmission in rat isolated urinary bladder. Eur J Pharmacol 449:301-309
14. Melvin JE, Hamill RW (1987) The major pelvic ganglion: Androgen control of postnatal development. J Neurosci 7:1607-1612
15. Keast JR (1999) The autonomic nerve supply of male sex organs - an important target of circulating androgens. Behav Brain Res 105:81-92
16. Morita T, Tsuchiya N, Tsujii T, Kondo S (1992) Changes of autonomic receptors following castration and estrogen administration in the male rabbit urethral smooth muscle. Tohoku J Exp Med 166:403-405
17. Giuliano F, Rampin O, Schirar A, Jardin A, Rousseau JP (1993) Autonomic control of penile erection: Modulation by testosterone in the rat. J Neuroendocrinol 5:677-683
18. Hypolite JA, Longhurst PA, Gong C, Briscoe J, Wein AJ, Levin RM (1993) Metabolic studies on rabbit bladder smooth muscle and mucosal epithelium. Mol Cell Biochem 125:35-42
19. Kubota Y, Hashitani H, Fukuta H, Kubota H, Kohri K, Suzuki H (2003) Role of mitochondria in the generation of spontaneous activity in detrusor smooth muscles of the Guinea pig bladder. J Urol 170:628-633
20. Pitteloud N, Mootha VK, Dwyer AA, Hardin M, Lee H, Eriksson KF, Tripathy D, Yialamas M, Groop L, Elahi D, Hayes FJ (2005) Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men. Diabetes Care 28:1636-1642
21. Pandita RK, Persson K, Hedlund P, Andersson KE (1998) Testosterone-induced prostatic growth in the rat causes bladder overactivity unrelated to detrusor hypertrophy. Prostate 35:102-108
22. Constantinou CE (1996) Influence of hormone treatment on prostate growth and micturition characteristics of the rat. Prostate 29:30-35
23. Liu L, Ishida Y, Okunade G, Shull GE, Paul RJ (2006) Role of plasma membrane Ca2+-ATPase in contraction-relaxation processes of the bladder: evidence from PMCA gene-ablated mice. Am J Physiol Cell Physiol 290:C12391247