Pancreatic intraepithelial neoplasia and ductal adenocarcinoma induced by DMBA in mice. Effects of alcohol and caffeine

Acta Cirurgica Brasileira

Volumn 22, Issue 3, 2007, Pages 202-209

  Wendt, Luiz Roberto Rigo ^a,c   Osvaldt, Alessandro Bersch ^a   Bersch, Vivian Pierre ^a   Schumacher, Rita De Cássia ^a   Edelweiss, Maria Isabel Albano ^a   Rohde, Luiz ^a,b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^c Engenheiro Alvaro Nunes Pereira   (Brazil)

Author keywords

9,10 Dimethyl 1,2 benzanthracene; Adenocarcinoma; Caffeine; Mice; Pancreas

Indexed keywords

ALCOHOL; CAFFEINE; DIMETHYLBENZ[A]ANTHRACENE; DRINKING WATER; EOSIN; FORMALDEHYDE; HEMATOXYLIN; WATER;

ANIMAL EUTHANASIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER MODEL; CARCINOGENESIS; CONTROLLED STUDY; DISEASE CLASSIFICATION; EPITHELIUM TUMOR; MALE; MOUSE; NONHUMAN; PANCREAS; PANCREAS ADENOCARCINOMA; PANCREAS DUCT; PANCREAS TUMOR;

EID: 34250183094     PISSN: 01028650     EISSN: 16782674     Source Type: Journal    
DOI: 10.1590/S0102-86502007000300008     Document Type: Article

References (41)

1. DiMagno EP, Reber HA, Tempero MA. AGA technical review on the epidemiology, diagnosis, and treatment of pancreatic ductal adenocarcinoma. American Gastroenterological Association. Gastroenterology. 1999; 117(6):1464-84.
2. Yeo TP, Hruban RH, Leach SD, Wilentz RE, Sohn TA, Kern SE, Iacobuzio-Donahue CA, Maitra A, Goggins M, Canto MI, Abrams RA, Laheru D, Jaffee EM, Hidalgo M, Yeo CJ. Pancreatic cancer. Curr Probl Cancer. 2002; 26(4):176-275.
3. Jemal A, Murray T, Samuels A, Ghafoor A, Ward E, Thun MJ. Cancer statistics, 2003. Cancer J Clin. 2003; 53(1):5-26.
4. Hruban RH, Takaori K, Klimstra DS, Adsay NV, Albores-Saavedra J, Biankin AV, Biankin SA, Compton C, Fukushima N, Furukawa T, Goggins M, Kato Y, Kloppel G, Longnecker DS, Luttges J, Maitra A, Offerhaus GJ, Shimizu M, Yonezawa S. An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms. Am J Surg Pathol. 2004; 28(8):977-87.
5. Hruban RH, Adsay NV, Albores-Saavedra J, Compton C, Garrett ES, Goodman SN, Kern SE, Klimstra DS, Kloppel G, Longnecker DS, Luttges J, Offerhaus GJ. Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesions. Am J Surg Pathol. 2001; 25(5):579-86.
6. Maitra A, Adsay NV, Argani P, Iacobuzio-Donahue C, De Marzo A, Cameron JL, Yeo CJ, Hruban RH. Multicomponent analysis of the pancreatic adenocarcinoma progression model using a pancreatic intraepithelial neoplasia tissue microarray. Mod Pathol. 2003; 16(9):902-12.
7. Takaori K, Hruban RH, Maitra A, Tanigawa N. Pancreatic intraepithelial neoplasia. Pancreas. 2004; 28(3):257-62.
8. Hruban RH, Iacobuzio-Donahue C, Wilentz RE, Goggins M, Kern SE. Molecular pathology of pancreatic cancer. Cancer J. 2001; 7(4):251-8.
9. Hotz HG, Hines OJ, Foitzik T, Reber HA. Animal models of exocrine pancreatic cancer. Int J Colorectal Dis. 2000; 15(3):136-43.
10. Dissin J, Mills LR, Mains DL, Black O, Jr., Webster PD, III. Experimental induction of pancreatic adenocarcinoma in rats. J Natl Cancer Inst. 1975; 55(4):857-64.
11. Rivera JA, Graeme-Cook F, Werner J, Z'graggen K, Rustgi AK, Rattner DW, Warshaw AL, Fernandez-Del Castillo C. A rat model of pancreatic ductal adenocarcinoma: targeting chemical carcinogens. Surgery. 1997; 122(1):82-90.
12. Bockman DE, Black O, Jr., Mills LR, Mainz DL, Webster PD, III. Fine structure of pancreatic adenocarcinoma induced in rats by 7,12-dimethylbenz(a) anthracene. J Natl Cancer Inst. 1976; 57(4):931-6.
13. Jimenez RE, Z'graggen K, Hartwig W, Graeme-Cook F, Warshaw AL, Fernandez-Del Castillo C. Immunohistochemical characterization of pancreatic tumors induced by dimethylbenzanthracene in rats. Am J Pathol. 1999; 154(4):1223-9.
14. Zehnder P, Z'Graggen K, Ozawa F, Mazzucchelli L, Büchler MW. First description of a carcinogen induced mouse model of ductal pancreatic adenocarcinoma: dimethylbenzanthraceno induces ductal adenocaarcinoma of the pancreas in a dysplasiacarcinoma type sequence. HPB Surg. 2000; 2(2):124.
15. Osvaldt AB, Wendt LR, Backes AN, Schumacher RC, Bersch VP, Edelweiss MIA, Rohde L. Pancreatic intraepithelial neoplasia and ductal adenocarcinoma induced by DMBA in mice. Surgery. 2006;140:803-9.
16. Z'graggen K, Warshaw AL, Werner J, Graeme-Cook F, Jimenez RE, Fernandez-Del Castillo C. Promoting effect of a high-fat/high-protein diet in DMBA-induced ductal pancreatic cancer in rats. Ann Surg. 2001; 233(5):688-95.
17. Commission on Life Sciences National Research Council. Guide for care and use of laboratory animals. 7ed. Washington DC: National Academy Press; 1996.
18. Kloppel G, Luttges J. WHO-classification 2000: exocrine pancreatic tumors. Verh Dtsch Ges Pathol. 2001; 85:219-28.
19. Klimstra DS, Longnecker DS. K-ras mutations in pancreatic ductal proliferative lesions. Am J Pathol. 1994; 145(6):1547-50.
20. Bockman DE, Guo J, Buchler P, Muller MW, Bergmann F, Friess H. Origin and development of the precursor lesions in experimental pancreatic cancer in rats. Lab Invest. 2003; 83(6):853-9.
21. Hingorani SR, Petricoin EF, Maitra A, Rajapakse V, King C, Jacobetz MA, Ross S, Conrads TP, Veenstra TD, Hitt BA, Kawaguchi Y, Johann D, Liotta LA, Crawford HC, Putt ME, Jacks T, Wright CV, Hruban RH, Lowy AM, Tuveson DA. Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell. 2003; 4(6):437-50.
22. Maitra A, Fukushima N, Takaori K, Hruban RH. Precursors to invasive pancreatic cancer. Adv Anat Pathol. 2005; 12(2):81-91.
23. Li D, Xie K, Wolff R, Abbruzzese JL. Pancreatic cancer. Lancet. 2004; 363(9414):1049-57.
24. Boyle P, Maisonneuve P, Bueno dM, Ghadirian P, Howe GR, Zatonski W, Baghurst P, Moerman CJ, Simard A, Miller AB, Przewoniak K, McMichael AJ, Hsieh CC, Walker AM. Cigarette smoking and pancreas cancer: a case control study of the search programme of the IARC. Int J Cancer. 1996; 67(1):63-71.
25. Simon B, Printz H. Epidemiologic Trends in Pancreatic Neoplasias. Dig Dis. 2001; 19(1):6-14.
26. Lowenfels AB, Maisonneuve P. Environmental factors and risk of pancreatic cancer. Pancreatology. 2003; 3(1):1-7.
27. Martin JB, Annegers JF, Curb JD, Heyden S, Howson C, Lee ES, Lee M. Mortality patterns among hypertensives by reported level of caffeine consumption. Prev Med. 1988; 17(3):310-20.
28. Porta M, Malats N, Alguacil J, Ruiz L, Jariod M, Carrato A, Rifa J, Guarner L. Coffee, pancreatic cancer, and K-ras mutations: updating the research agenda. J Epidemiol Community Health. 2000; 54(9):656-9.
29. Heuch I, Kvale G, Jacobsen BK, Bjelke E. Use of alcohol, tobacco and coffee, and risk of pancreatic cancer. Br J Cancer. 1983; 48(5):637-43.
30. Vineis P. ras Mutations and a cup of coffee: cause, confounder, effect modifier, or what else? J Epidemiol Community Health. 1999; 53(11):685.
31. Villeneuve PJ, Johnson KC, Hanley AJ, Mao Y. Alcohol, tobacco and coffee consumption and the risk of pancreatic cancer: results from the Canadian enhanced surveillance system case-control project. Canadian Cancer Registries Epidemiology Research Group. Eur J Cancer Prev. 2000; 9(1):49-58.
32. Michaud DS, Giovannucci E, Willett WC, Colditz GA, Fuchs CS. Coffee and alcohol consumption and the risk of pancreatic cancer in two prospective United States cohorts. Cancer Epidemiol Biomarkers Prev. 2001; 10(5):429-37.
33. Longnecker MP. Alcohol consumption and risk of cancer in humans: an overview. Alcohol. 1995; 12(2):87-96.
34. Longnecker MP, Enger SM. Epidemiologic data on alcoholic beverage consumption and risk of cancer. Clin Chim Acta. 1996; 246(1-2):121-41.
35. Ye W, Lagergren J, Weiderpass E, Nyren O, Adami HO, Ekbom A. Alcohol abuse and the risk of pancreatic cancer. Gut. 2002; 51(2):236-9.
36. Lin Y, Tamakoshi A, Kawamura T, Inaba Y, Kikuchi S, Motohashi Y, Kurosawa M, Ohno Y. Risk of pancreatic cancer in relation to alcohol drinking, coffee consumption and medical history: findings from the Japan collaborative cohort study for evaluation of cancer risk. Int J Cancer. 2002; 99(5):742-6.
37. Singh M, Simsek H. Ethanol and the pancreas. Current status. Gastroenterology. 1990; 98(4):1051-62.
38. Lowenfels AB, Maisonneuve P, Cavallini G, Ammann RW, Lankisch PG, Andersen JR, DiMagno EP, Andren-Sandberg A, Domellof L. Pancreatitis and the risk of pancreatic cancer. International Pancreatitis Study Group. N Engl J Med. 1993; 328(20):1433-7.
39. International Agency for Research on Cancer. Certain polycyclic aromatic hydrocarbons and heterocyclic compounds. Available from : http://monographs. iarc.fr/htdocs/monographs/vol32/benz%5Ba%5Danthracene.html [Acessed July 2, 2004].
40. Li D, Jiao L. Molecular epidemiology of pancreatic cancer. Int J Gastrointest Cancer. 2003; 33(1):3-14.
41. Rosty C, Geradts J, Sato N, Wilentz RE, Roberts H, Sohn T, Cameron JL, Yeo CJ, Hruban RH, Goggins M. p16 Inactivation in pancreatic intraepithelial neoplasias (PanINs) arising in patients with chronic pancreatitis. Am J Surg Pathol. 2003; 27(12):1495-501.