Synthesis and anthelmintic activity of cyclohexadepsipeptides with cyclohexylmethyl side chains

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 13, 2007, Pages 3690-3695

  Jeschke, Peter ^a   Harder, Achim ^a   Etzel, Winfried ^a   Schindler, Michael ^a   Thielking, Gerhard ^a  

^a BAYER CROPSCIENCE AG   (Germany)

Author keywords

cis Amide bond; Conformer; Cyclohexadepsipeptides; Enniatin; Haemonchus contortus; Nematode; Total synthesis

Indexed keywords

ANTHELMINTIC AGENT; CYCLOHEXADEPSIPEPTIDE; ENNIATIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTHELMINTIC ACTIVITY; ARTICLE; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; HAEMONCHUS CONTORTUS; HYDROGENATION; IN VIVO STUDY; NEMATODIASIS; NONHUMAN; SPECTROSCOPY;

ANIMALS; ANTHELMINTICS; CATALYSIS; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; HAEMONCHUS; HUMANS; HYDROGEN; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MODELS, CHEMICAL; PEPTIDES; PEPTIDES, CYCLIC; SHEEP; SHEEP DISEASES;

HAEMONCHUS CONTORTUS; OVIS ARIES;

EID: 34250173122     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.04.037     Document Type: Article

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