Clinical significance of silent cerebral infarctions in patients with Alzheimer disease

Cognitive and Behavioral Neurology

Volumn 20, Issue 2, 2007, Pages 93-98

  Song, In Uk ^a   Kim, Joong Seok ^a   Kim, Yeong In ^a   Eah, Kyung Yoon ^b   Lee, Kwang Soo ^a,c  

^a The Catholic University of Korea   (South Korea)

^b Dongguk University   (South Korea)

^c The Catholic University of Korea   (South Korea)

Author keywords

Alzheimer disease; Cognitive decline; Silent cerebral infarctions

Indexed keywords

AGED; ALZHEIMER DISEASE; ARTICLE; ATTENTION; BRAIN FUNCTION; BRAIN INFARCTION; CLINICAL FEATURE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DEPTH PERCEPTION; FEMALE; FRONTAL CORTEX; HUMAN; LANGUAGE; MAJOR CLINICAL STUDY; MALE; MEMORY; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; RECALL; SAMPLE SIZE; SEMANTIC MEMORY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ANALYSIS OF VARIANCE; CASE-CONTROL STUDIES; CEREBRAL INFARCTION; COGNITION DISORDERS; FRONTAL LOBE; HUMANS; MAGNETIC RESONANCE IMAGING; MATCHED-PAIR ANALYSIS; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; SEVERITY OF ILLNESS INDEX; STATISTICS, NONPARAMETRIC; TEMPORAL LOBE;

EID: 34250170146     PISSN: 15433633     EISSN: None     Source Type: Journal    
DOI: 10.1097/WNN.0b013e31805d859e     Document Type: Article

References (30)

1. Rekse RG, Leverenz JB, McCormick W, et al. Effect of vascular lesions on cognition in Alzheimer's disease: a community-based study. J Am Geriatr Soc. 2004;52:1442-1448.
2. Jellinger KA, Mitter-Ferstl E. The impact of cerebrovascular lesions in Alzheimer disease; a comparative autopsy study. J Neurol. 2003;250:1050-1055.
3. Vermeer SE, Prins ND, Heijer ED, et al. Silent brain infarcts and the risk of dementia and cognitive decline. N Engl J Med. 2003;348:1215-1222.
4. Lee JH, Olichney JM, Hansen LA, et al. Small concomitant vascular lesions do not influence rates of cognitive decline in patients with Alzheimer disease. Arch Neurol. 2000;57:1474-1479.
5. Snowdon DA, Greiner LH, Mortimer JA, et al. Brain infarction and the clinical expression of Alzheimer disease. The Nun Study. JAMA. 1997;277:813-817.
6. Esiri MM, Nagy Z, Smith MZ, et al. Cerebrovascular disease and threshold for dementia in the early stages of Alzheimer's disease. Lancet. 1999;354:919-920.
7. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. Fourth Edition (DSM-IV). Washington, DC: American Psychiatric Association; 1994:143-147.
8. McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task force in Alzheimer's disease. Neurology. 1984;34:939-944.
9. Erkinjuntti T, Inzitari D, Pantoni L, et al. Research criteria for subcortical vascular dementia in clinical trials. J Neural Transm Suppl. 2000;59:23-30.
10. Roman GC, Tatemichi TK, Erkinjuntti T, et al. Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology. 1993;43:250-260.
11. Selden NR, Gitelman DR, Salamon-Murayama N, et al. Trajectories of cholinergic pathways within the cerebral hemispheres of the human brain. Brain. 1998;121:2249-2257.
12. Hachinski VS, Iliff LD, Zilhka E, et al. Cerebral blood flow in dementia. Arch Neurol. 1975;32:632-637.
13. Kang YW, Na DL, Hahn SH. A Validity Study on the Korean Mini-Mental State Examination (K-MMSE) in Dementia Patients. J Korean Neurol Assoc. 1997;15:300-308.
14. Choi SH, Na DL, Lee BH, et al. Estimating the Validity of the Korean version of Expanded clinical Dementia Rating (CDR) Scale. J Korean Neurol Assoc. 2001;19:585-591.
15. Kang YW. Samsung Neuropsychological Screening Battery. In: Current Research in Dementia. Seoul: The Korean Dementia Association. 1998:99-107.
16. Kim H, Na DL. Korean-Boston Naming Test. Seoul: Hakji Co; 1997.
17. Kim E, Kim H, Na DL. Naming deficits in patients with dementia of the Alzheimer type: error analysis of Korean version-Boston Naming Test. J Korean Neurol Assoc. 1997;15:1012-1021.
18. Kalaria RN. The role of cerebral ischemia in Alzheimer's disease. Neurobiol Aging. 2000;21:321-330.
19. Silvestrini M, Pasqualetti P, Baruffaldi R, et al. Cerebrovascular reactivity and cognitive decline in patients with Alzheimer disease. Stroke. 2006;37:1010-1015.
20. Neuropathology Group of the Medical Research Council Cognitive Function and Aging Study (MRC CFAS). Pathologic correlates of late onset dementia in a multicentre, community based population in England and Wales. Lancet. 2001;357:169-175.
21. Mendonca AD, Ribeiro F, Guerreiro M, et al. Clinical significance of subcortical vascular disease in patients with mild cognitive impairment. Eur J Neurol. 2005;12:125-130.
22. Schneider FA, Wilson RS, Cochran EJ, et al. Relation of cerebral infarctions to dementia and cognitive function in older persons. Neurology. 2003;60:1082-1088.
23. O'Brien J, Lilienfeld S. Relevant clinical outcomes in probable vascular dementia and Alzheimer's disease with cerebrovascular disease. J Neurol Sci. 2002;203-204:41-48.
24. Schmidtke K, Hull M. Neuropsychological differentiation of small vessel disease, Alzheimer's disease and mixed dementia. J Neurol Sci. 2002;203-204:17-22.
25. Cummings JL. Frontal-subcortical circuits and human behavior. Arch Neurol. 1993;50:873-880.
26. Wardlaw JM, Sandercock PAG, Dennis MS, et al. Is breakdown of the blood-brain barrier responsible for lacunar stroke, leukoaraiosis, and dementia? Stroke. 2003;34:806-812.
27. Starkstein SE, Almerda OP. Understanding cognitive impairment and dementia: stroke studies. Curr Opin Psychiatry. 2003;16:615-620.
28. Kalaria R. Similarities between Alzheimer's disease and vascular dementia. J Neurol Sci. 2002;203-204:29-34.
29. Exel EV, Gussekloo J, Houx P, et al. Atherosclerosis and cognitive impairment are linked in the elderly. The Leiden 85-plus Study. Atherosclerosis. 2002;165:353-359.
30. Stern Y. Cognitive reserve and Alzheimer disease. Alzheimer Dis Assoc Disord. 2006;20:112-117.