Lead levels and ischemic heart disease in a prospective study of middle-aged and elderly men: The VA normative aging study

Environmental Health Perspectives

Volumn 115, Issue 6, 2007, Pages 871-875

  Jain, Nitin B ^a,b   Potula, Vijayalakshmi ^c   Schwartz, Joel ^d   Vokonas, Pantel S ^e   Sparrow, David ^a,e   Wright, Robert O ^a,d   Nie, Huiling ^a,d   Hu, Howard ^a,d  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b Programs in Research   (United States)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angina; Epidemiology; Myocardial infarction

Indexed keywords

BIOLOGICAL MARKER; LEAD;

ACCURACY; ADULT; AGED; ANGINA PECTORIS; ARTICLE; BONE LEVEL; CARDIOLOGIST; COHORT ANALYSIS; CONTROLLED STUDY; DEATH CERTIFICATE; DISEASE ASSOCIATION; ECG ABNORMALITY; ENVIRONMENTAL EXPOSURE; FOLLOW UP; HEART INFARCTION; HUMAN; HYPERTENSION; ISCHEMIC HEART DISEASE; LEAD BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MEDICAL ASSESSMENT; MORTALITY; MULTIVARIATE ANALYSIS; PATELLA; PATHOGENESIS; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; RISK ASSESSMENT; RISK FACTOR; TIBIA;

AGED; COHORT STUDIES; HUMANS; LEAD; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; PATELLA; PROSPECTIVE STUDIES; RISK FACTORS; TIBIA; UNITED STATES; VETERANS;

ANGINA;

EID: 34250161637     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.9629     Document Type: Article

References (49)

1. Barry PS, Mossman DB. 1970. Lead concentrations in human tissues. Br J Ind Med 27(4):339-351.
2. Barzilay JI, Kronmal RA, Bittner V, Eaker E, Foster ED. 1998. Coronary artery disease in diabetic and nondiabetic patients with lower extremity arterial disease: a report from the Coronary Artery Surgery Study Registry. Am Heart J 135(6 Pt 1):1055-1062.
3. Bell B, Rose C, Damon A. 1972. The Normative Aging Study: an interdisciplinary and longitudinal study of health and aging. Aging Human Develop 3:4-17.
4. Burger DE, Milder FL, Morsillo PR, Adams BB, Hu H, 1990. Automated bone lead analysis by K-x-ray fluorescence for the clinical environment. Basic Life Sci 55:287-292.
5. Castelli WP, Wilson PW, Levy D, Anderson K. 1989. Cardiovascular risk factors in the elderly. Am J Cardiol 63(16):12H-19H.
6. Cheng Y, Schwartz J, Sparrow D, Aro A, Weiss ST, Hu H. 2001. Bone lead and blood lead levels in relation to baseline blood pressure and the prospective development of hypertension: the Normative Aging Study. Am J Epidemiol 153(2):164-171.
7. Ferris BG. 1978. Epidemiology Standardization Project (American Thoracic Society). Am Rev Respir Dis 118(6 Pt 2): 1-120.
8. Gordon CL, Chettle DR, Webber CE. 1993. An improved instrument for the in vivo detection of lead in bone. Br J Ind Med 50(7):637-641.
9. Harlan WR. 1988. The relationship of blood lead levels to blood pressure in the U.S. population. Environ Health Perspect 78:9-13.
10. Hertz-Picciotto I, Croft J. 1993. Review of the relation between blood lead and blood pressure. Epidemiol Rev 15(2):352-373.
11. Hu H, Aro A, Payton M, Korrick S, Sparrow D, Weiss ST, et al. 1996a. The relationship of bone and blood lead to hypertension. The Normative Aging Study. JAMA 275(15):1171-1176.
12. Hu H, Milder FL, Burger DE. 1990. X-ray fluorescence measurements of lead burden in subjects with low-level community lead exposure. Arch Environ Health 45(6):335-341.
13. Hu H, Payton M, Korrick S, Aro A, Sparrow D, Weiss ST, et al. 1996b. Determinants of bone and blood lead levels among community-exposed middle-aged to elderly men: the Normative Aging Study. Am J Epidemiol 144:749-759.
14. Hu H, Watanabe H, Payton M, Korrick S, Rotnitzky A. 1994. The relationship between bone lead and hemoglobin. JAMA 272(19):1512-1517.
15. 109Cd source. In: In Vivo Body Composition Studies (Ellis KJ, Yasumura S, Morgan WD, eds). London:Institute of Physical Sciences in Medicine, 363-373.
16. Khot UN, Khot MB, Bajzer CT, Sapp SK, Ohman EM, Brener SJ, et al. 2003. Prevalence of conventional risk factors in patients with coronary heart disease. JAMA 290(7):898-904.
17. Kim R, Aro A, Rotnitzky A, Amarasiriwardena C, Hu H. 1995. K x-ray fluorescence measurements of bone lead concentration: the analysis of low-level data. Phys Med Biol 40(9):1475-1485.
18. Kopp SJ, Barron JT, Tow JP. 1988. Cardiovascular actions of lead and relationship to hypertension: a review. Environ Health Perspect 78:91-99.
19. Kosnett MJ, Becker CE, Osterloh JD, Kelly TJ, Pasta DJ. 1994. Factors influencing bone lead concentration in a suburban community assessed by noninvasive K x-ray fluorescence. JAMA 271(3):197-203.
20. Kromhout D. 1988. Blood lead and coronary heart disease risk among elderly men in Zutphen, the Netherlands. Environ Health Perspect 78:43-46.
21. Landrigan PJ. 1991. Strategies for epidemiologic studies of lead in bone in occupationally exposed populations. Environ Health Perspect 91:81-86.
22. Landrigan PJ, Todd AC. 1994. Direct measurement of lead in bone. A promising biomarker. JAMA 271(3):239-240.
23. Lin JL, Lin-Tan DT, Hsu KH, Yu CC. 2003. Environmental lead exposure and progression of chronic renal diseases in patients without diabetes. N Engl J Med 348(4):277-286.
24. Lustberg M, Silbergeld E. 2002. Blood lead levels and mortality. Arch Intern Med 162(21):2443-2449.
25. MacMahon S, Peto R, Cutler J, Collins R, Sorlie P, Neaton J, et al. 1990. Blood pressure, stroke, and coronary heart disease. Part 1, Prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias. Lancet 335(8692):765-774.
26. Manton WI. 1985. Total contribution of airborne lead to blood lead. Br J Ind Med 42(3):168-172.
27. Martin D, Glass TA, Bandeen-Roche K, Todd AC, Shi W, Schwartz BS. 2006. Association of blood lead and tibia lead with blood pressure and hypertension in a community sample of older adults. Am J Epidemiol 163(5):467-478.
28. Moller L, Kristensen TS. 1992. Blood lead as a cardiovascular risk factor. Am J Epidemiol 136(9):1091-1100.
29. Nash D, Magder L, Lustberg M, Sherwin RW, Rubin RJ, Kaufmann RB, et al. 2003. Blood lead, blood pressure, and hypertension in perimenopausal and postmenopausal women. JAMA 289(12):1523-1532.
30. Oneglia C, Apostoli P, Rusconi C. 1998. Vasospastic angina in a patient with chronic lead intoxication: a possible cause-effect relationship? Cardiovasc Drugs Ther 12(1):71-73.
31. Pirkle JL, Brody DJ, Gunter EW, Kramer RA, Paschal DC, Flegal KM, et al. 1994. The decline in blood lead levels in the United States. The National Health and Nutrition Examination Surveys (NHANES). JAMA 272(4):284-291.
32. Pirkle JL, Schwartz J, Landis JR, Harlan WR. 1985. The relationship between blood lead levels and blood pressure and its cardiovascular risk implications. Am J Epidemiol 121(2):246-258.
33. Pocock SJ, Shaper AG, Ashby D, Delves HT, Clayton BE. 1988. The relationship between blood lead, blood pressure, stroke, and heart attacks in middle-aged British men. Environ Health Perspect 78:23-30.
34. Rabinowitz MB. 1991. Toxicokinetics of bone lead. Environ Health Perspect 91:33-37.
35. Rabinowitz MB, Wetherill GW, Kopple JD. 1976. Kinetic analysis of lead metabolism in healthy humans. J Clin Invest 58(2):260-270.
36. Saltzman BE, Gross SB, Yeager DW, Meiners BG, Gartside PS. 1990. Total body burdens and tissue concentrations of lead, cadmium, copper, zinc, and ash in 55 human cadavers. Environ Res 52(2):126-145.
37. Schroeder HA, Tipton IH. 1968. The human body burden of lead. Arch Environ Health 17(6):965-978.
38. Schwartz BS, Stewart WF, Bolla KI, Simon PD, Bandeen-Roche K, Gordon PB, et al. 2000. Past adult lead exposure is associated with longitudinal decline in cognitive function. Neurology 55(8):1144-1150.
39. Schwartz J. 1991. Lead, blood pressure, and cardiovascular disease in men and women. Environ Health Perspect 91:71-75.
40. Schwartz J. 1995. Lead, blood pressure, and cardiovascular disease in men. Arch Environ Health 50:31-37.
41. Shurtleff D. 1974. Some Characteristics Related to the Incidence of Cardiovascular Disease and Death: Framingham Study, 18-Year Follow-up. Bethesda, MD:U.S. Department of Health, Education, and Welfare.
42. Silbergeld EK. 1991. Lead in bone: implications for toxicology during pregnancy and lactation. Environ Health Perspect 91:63-70.
43. Somervaille LJ, Chettle DR, Scott MC. 1985. In vivo measurement of lead in bone using x-ray fluorescence. Phys Med Biol 30(9):929-943.
44. Tibblin G, Wilhelmsen L, Werko L. 1975. Risk factors for myocardial infarction and death due to ischemic heart disease and other causes. Am J Cardiol 35(4):514-522.
45. Tsaih SW, Korrick S, Schwartz J, Amarasiriwardena C, Aro A, Sparrow D, et al. 2004. Lead, diabetes, hypertension, and renal function: the Normative Aging Study. Environ Health Perspect 112:1178-1182.
46. Ward KD, Sparrow D, Vokonas PS, Willett WC, Landsberg L, Weiss ST. 1994. The relationships of abdominal obesity, hyperinsulinemia and saturated fat intake to serum lipid levels: the Normative Aging Study. Int J Obes Relat Metab Disord 18(3):137-144.
47. Weisskopf MG, Wright RO, Schwartz J, Spiro A III, Sparrow D, Aro A, et al. 2004. Cumulative lead exposure and prospective change in cognition among elderly men: the VA Normative Aging Study. Am J Epidemiol 160(12):1184-1193.
48. Willett WC, Sampson L, Browne ML, Stampfer MJ, Rosner B, Hennekens CH, et al. 1988. The use of a self-administered questionnaire to assess diet four years in the past. Am J Epidemiol 127(1):188-199.
49. Wojtczak-Jaroszowa J, Kubow S. 1989. Carbon monoxide, carbon disulfide, lead and cadmium - four examples of occupational toxic agents linked to cardiovascular disease. Med Hypotheses 30(2):141-150.