Antibacterial nicotinamide adenine dinucleotide synthetase inhibitors: Amide- and ether-linked tethered dimers with α-amino acid end groups

Journal of Medicinal Chemistry

Volumn 50, Issue 11, 2007, Pages 2612-2621

  Velu, Sadanandan E ^a   Mou, Liyuan ^a   Luan, Chi Hao ^a   Yang, Zhengrong W ^a   DeLucas, Lawrence J ^a   Brouillette, Christie G ^a   Brouillette, Wayne J ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 BENZYLOXYPHENOXY) 8 (2 GUANIDINO 2 PHENYL 1 ETHYLOXY)OCTANE; 1 (4 BENZYLOXYPHENOXY) 8 (2 GUANIDINO 3 PHENYL 1 PROPYLOXY)OCTANE; 1 (4 BENZYLOXYPHENOXY) 8 (2 N,N' BIS TERT BUTOXYCARBONYLGUANIDINO) 3 PHENYL 1 PROPYLOXY)OCTANE; 1 (4 BENZYLOXYPHENOXY) 8 (2 N,N,N TRIMETHYLAMMONIUM 3 PHENYL 1 PROPYLOXY)OCTANE; 1 (4 BENZYLOXYPHENOXY) 8[2 (N TERT BUTOXYCARBONYLAMINO) 2 PHENYL 1 ETHYLOXY]OCTANE; 1 (4 BENZYLOXYPHENOXY) 8[2 (N TERT BUTOXYCARBONYLAMINO) 3 PHENYL 1 PROPYLOXY]OCTANE; 8 (4 BENZYLOXYPHENOXY) 1 OCTYL 2 (N TERT BUTOXYCARBONYLAMINO) 3 (1H INDOL 3 YL)PROPIONIC ACID; 8 (4 BENZYLOXYPHENOXY) 1 OCTYL 2 (N TERT BUTOXYCARBONYLAMINO) 3 (4 TERT BUTOXYPHENYL)PROPIONIC ACID; 8 (4 BENZYLOXYPHENOXY) 1 OCTYL 2 (N,N,N TRIMETHYLAMMONIUM) 3 (4 HYDROXYPHENYL)PROPIONIC ACID; 8 (4 BENZYLOXYPHENOXY) 1 OCTYL 2 (N,N,N TRIMETHYLAMMONIUM) 3 PHENYLPROPIONIC ACID; 8 (4 BENZYLOXYPHENOXY) 1 OCTYL 2 AMINO 3 (1H INDOL 3 YL)PROPIONIC ACID; 8 (4 BENZYLOXYPHENOXY) 1 OCTYL 2 AMINO 3 (4 HYDROXYPHENYL)PROPIONIC ACID; 8 (4 BENZYLOXYPHENOXY) 1 OCTYL 2 AMINO 3 PHENYLPROPIONIC ACID; 8 (4 BENZYLOXYPHENOXY) 1 OCTYLAMINE; ALPHA AMINO ACID; AMIDE; ANTIBIOTIC AGENT; ETHER; N [8 (4 BENZYLOXYOHENOXY) 1 OCTYL] PHTHALIMIDE; N [8 (4 BENZYLOXYPHENOXY) 1 OCTYL] 2 (N TERT BUTOXYCARBONYLAMINO) 3 PHENYLPROPIONAMIDE; N [8 (4 BENZYLOXYPHENOXY) 1 OCTYL] 2 (N' TERT BUTOXYCARBONYLAMINO) 2 PHENYLACETAMIDE; N [8 (4 BENZYLOXYPHENOXY) 1 OCTYL] 2 AMINO 3 PHENYLPROPIONAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE SYNTHETASE INHIBITOR; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DETERMINATION; DRUG STRUCTURE; ENZYME INHIBITION; GRAM NEGATIVE BACTERIUM; NONHUMAN;

AMIDE SYNTHASES; AMIDES; AMINO ACIDS; ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; DETERGENTS; DIMERIZATION; ETHERS; GRAM-POSITIVE BACTERIA; MICROBIAL SENSITIVITY TESTS; NAD; OCTOXYNOL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34250161577     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm061349l     Document Type: Article

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