Convergent solid-phase peptide synthesis performed in a CHCl 3-phenol mixed solvent: Synthesis of amyloid β-peptides as examples with a difficult sequence

International Journal of Peptide Research and Therapeutics

Volumn 13, Issue 1-2, 2007, Pages 119-128

  Nishiuchi, Yuji ^a   Nishio, Hideki ^a   Ishimaru, Masanori ^a   Kimura, Terutoshi ^a  

^a Peptide Institute Inc   (Japan)

Author keywords

A mixture of CHCl3 and phenol; Amyloid peptide; Convergent solid phase peptide synthesis; Epimerization; Ester formation

Indexed keywords

AMINO ACID DERIVATIVE; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[40-1]; CARBONYL DERIVATIVE; CHLORINE DERIVATIVE; N,N DIMETHYLFORMAMIDE; PEPTIDE DERIVATIVE; PHENOL; RESIN; SOLVENT; UNCLASSIFIED DRUG;

AMINO ACID SYNTHESIS; ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; EPIMERIZATION; PEPTIDE SYNTHESIS; REACTION ANALYSIS; SEQUENCE ANALYSIS; SOLID PHASE SYNTHESIS; SOLVENT EFFECT;

EID: 34250011248     PISSN: 15733149     EISSN: 15733904     Source Type: Journal    
DOI: 10.1007/s10989-006-9054-z     Document Type: Article

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