A minor role for Ca2+ sensitization in sustained contraction through activation of muscarinic receptor in circular muscle of rat distal colon

Pflugers Archiv European Journal of Physiology

Volumn 454, Issue 4, 2007, Pages 565-574

  Takeuchi, Tadayoshi ^a   Nakajima, Hidemitsu ^a   Hata, Fumiaki ^a   Azuma, Yasu Taka ^a  

^a Osaka Prefecture University   (Japan)

Author keywords

a Rho kinase inhibitor; Ca2+ sensitization; Circular muscle; Intracellular Ca 2+; Muscarinic receptor; Protein kinase C; Rat distal colon

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ALPHA TOXIN; CALCIUM; CARBACHOL; CHELERYTHRINE; GUANOSINE TRIPHOSPHATE; MUSCARINIC RECEPTOR; PHORBOL DIBUTYRATE; ALKALOID; AMIDE; BENZOPHENANTHRIDINE DERIVATIVE; CARCINOGEN; CENTRAL MUSCLE RELAXANT; CHOLINERGIC RECEPTOR STIMULATING AGENT; PYRIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DESCENDING COLON; INTESTINE CONTRACTION; INTESTINE FUNCTION; INTRACELLULAR RECORDING; MALE; MUSCLE CONTRACTILITY; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIZATION; SMOOTH MUSCLE TONE; ANIMAL; COLON; DOSE RESPONSE; DRUG EFFECT; MUSCLE CONTRACTION; PHYSIOLOGY; SMOOTH MUSCLE; WISTAR RAT;

ALKALOIDS; AMIDES; ANIMALS; BENZOPHENANTHRIDINES; CALCIUM; CARBACHOL; CARCINOGENS; CHOLINERGIC AGONISTS; COLON; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANOSINE TRIPHOSPHATE; MALE; MUSCLE CONTRACTION; MUSCLE RELAXANTS, CENTRAL; MUSCLE, SMOOTH; PHORBOL 12,13-DIBUTYRATE; PYRIDINES; RATS; RATS, WISTAR; RECEPTORS, MUSCARINIC;

EID: 34250007444     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-007-0221-7     Document Type: Article

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