The mouse polyubiquitin gene UbC is essential for fetal liver development, cell-cycle progression and stress tolerance

EMBO Journal

Volumn 26, Issue 11, 2007, Pages 2693-2706

  Ryu, Kwon Yul ^a   Maehr, René ^b   Gilchrist, Catherine A ^c   Long, Michael A ^d   Bouley, Donna M ^a   Mueller, Britta ^e   Ploegh, Hidde L ^e   Kopito, Ron R ^a  

^a STANFORD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^e WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Cellular stress; Gene expression; Liver development; Polyubiquitin; Ubiquitin

Indexed keywords

HEMAGGLUTININ; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; POLYUBIQUITIN; PROTEASOME INHIBITOR; UBIQUITIN C;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE; CELL PROLIFERATION; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; FETUS; FETUS LIVER; FIBROBLAST; GENE EXPRESSION; GENE LOCUS; HEAT SHOCK; LIVER DEVELOPMENT; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SENESCENCE; STATISTICAL SIGNIFICANCE; STEADY STATE; STRESS;

ANIMALS; CELL AGING; CELL CYCLE; CELL PROLIFERATION; FETAL DEVELOPMENT; FIBROBLASTS; GENE EXPRESSION REGULATION; GENES, ESSENTIAL; LIVER; MICE; MICE, KNOCKOUT; UBIQUITIN C;

MAMMALIA; MUS;

EID: 34250007128     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601722     Document Type: Article

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