Solid phase synthesis of dual labeled peptides: Development of cell permeable calpain specific substrates

International Journal of Peptide Research and Therapeutics

Volumn 13, Issue 1-2, 2007, Pages 83-91

  Polster, Brian M ^b   Arze, Rafael ^a   Lyttle, Matthew H ^a   Nicholls, David G ^b   Hudson, Derek ^a  

^a Biosearch Technologies Inc   (United States)

^b BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

Author keywords

Black Hole Quencher; CAL Fluor dye; Calpain substrates; Cell based assay(s); FRET protease assay; Solid phase peptide synthesis

Indexed keywords

CALPAIN; GLUTAMYLVALYLTYROSYLGLYCYLMETHIONYLMETHIONINE; GLYCYLSERYLGLYCYLTHREONYLSERYLSERINE; PEPTIDE; PROLYLLEUCYLPHENYLALANYLALANYLGLUTAMYLARGININE; PROTEINASE; THREONYLPROLYLLEUCYLLYSYLSERYLPROLYLPROLYLPROLYLPROLYLSERYLPROLYLARGININE; UNCLASSIFIED DRUG; VALYLVALYLGLUTAMINYLALANYLGLYCYLISOLEUCINE; VALYLVALYLTHREONYLALANYLGLUTAMYLALANINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE PERMEABILITY; DRUG MECHANISM; DRUG SYNTHESIS; ENZYME SPECIFICITY; ENZYME STABILITY; ENZYME SUBSTRATE; FLUORESCENCE RESONANCE ENERGY TRANSFER; NONHUMAN; PEPTIDE SYNTHESIS; RAT; SOLID PHASE SYNTHESIS;

EID: 34249983624     PISSN: 15733149     EISSN: 15733904     Source Type: Journal    
DOI: 10.1007/s10989-006-9049-9     Document Type: Article

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