Are Caenorhabditis elegans receptors useful targets for drug discovery: Pharmacological comparison of tyramine receptors with high identity from C. elegans (TYRA-2) and Brugia malayi (Bm4)

Molecular and Biochemical Parasitology

Volumn 154, Issue 1, 2007, Pages 52-61

  Smith, Katherine A ^a   Rex, Elizabeth B ^b   Komuniecki, Richard W ^a  

^a UNIVERSITY OF TOLEDO   (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

Brugia malayi; Caenorhabditis elegans; Nematode; Tyramine receptor

Indexed keywords

CHLORPROMAZINE; LYSERGIDE H 3; PHENTOLAMINE; RADIOISOTOPE; RECEPTOR; TYRA 2 RECEPTOR; TYRAMINE H 3; TYRAMINE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BRUGIA MALAYI; CAENORHABDITIS ELEGANS; CELL MEMBRANE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG TARGETING; GENOME; LIGAND BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; ORDO; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; BRUGIA MALAYI; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL LINE; CELL MEMBRANE; CHLORPROMAZINE; CLONING, MOLECULAR; HUMANS; LIGANDS; LYSERGIC ACID DIETHYLAMIDE; MOLECULAR SEQUENCE DATA; PHENTOLAMINE; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, BIOGENIC AMINE; SEQUENCE HOMOLOGY, AMINO ACID; TYRAMINE;

BRUGIA MALAYI; CAENORHABDITIS ELEGANS; NEMATODA;

EID: 34249936643     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2007.04.004     Document Type: Article

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