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Volumn 75, Issue 6, 2007, Pages 3021-3026

CD4+ lymphocytes and gamma interferon predominate in local immune responses in early experimental syphilis

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; MESSENGER RNA;

EID: 34249895885     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.01973-06     Document Type: Article
Times cited : (54)

References (35)
  • 1
    • 0032768794 scopus 로고    scopus 로고
    • T-cell responses to Treponema pallidum subsp. pallidum antigens during the course of experimental syphilis infection
    • Arroll, T. W., A. Centurion-Lara, S. A. Lukehart, and W. C. Van Voorhis. 1999. T-cell responses to Treponema pallidum subsp. pallidum antigens during the course of experimental syphilis infection. Infect. Immun. 67:4757-4763.
    • (1999) Infect. Immun , vol.67 , pp. 4757-4763
    • Arroll, T.W.1    Centurion-Lara, A.2    Lukehart, S.A.3    Van Voorhis, W.C.4
  • 2
    • 0026565367 scopus 로고
    • Macrophage-mediated killing of opsonized Treponema pallidum
    • Baker-Zander, S. A., and S. A. Lukehart. 1992. Macrophage-mediated killing of opsonized Treponema pallidum. J. Infect. Dis. 165:69-74.
    • (1992) J. Infect. Dis , vol.165 , pp. 69-74
    • Baker-Zander, S.A.1    Lukehart, S.A.2
  • 3
    • 0017177825 scopus 로고
    • Humoral immunity in experimental syphilis. II. The relationship of neutralizing factors in immune serum to acquired resistance
    • Bishop, N. H., and J. N. Miller. 1976. Humoral immunity in experimental syphilis. II. The relationship of neutralizing factors in immune serum to acquired resistance. J. Immunol. 117:197-207.
    • (1976) J. Immunol , vol.117 , pp. 197-207
    • Bishop, N.H.1    Miller, J.N.2
  • 4
    • 0021720340 scopus 로고
    • Humoral immunity in experimental syphilis: The demonstration of IgG as a treponemicidal factor in immune rabbit scrum
    • Blanco, D. R., J. N. Miller, and P. A. Hanff. 1984. Humoral immunity in experimental syphilis: the demonstration of IgG as a treponemicidal factor in immune rabbit scrum. J. Immunol. 133:2693-2697.
    • (1984) J. Immunol , vol.133 , pp. 2693-2697
    • Blanco, D.R.1    Miller, J.N.2    Hanff, P.A.3
  • 5
    • 0035173274 scopus 로고    scopus 로고
    • Dendritic cells phagocytose and are activated by Treponema pallidum
    • Bouis, D. A., T. G. Popova, A. Takashima, and M. V. Norgard. 2001. Dendritic cells phagocytose and are activated by Treponema pallidum. Infect. Immun. 69:518-528.
    • (2001) Infect. Immun , vol.69 , pp. 518-528
    • Bouis, D.A.1    Popova, T.G.2    Takashima, A.3    Norgard, M.V.4
  • 6
    • 0033557257 scopus 로고    scopus 로고
    • Treponema pallidum major sheath protein homologue TprK is a target of opsonic antibody and the protective immune response
    • Centurion-Lara, A., C. Castro, L. Barrett, C. Cameron, M. Mostowfi, W. C. Van Voorhis, and S. A. Lukehart. 1999. Treponema pallidum major sheath protein homologue TprK is a target of opsonic antibody and the protective immune response. J. Exp. Med. 189:647-656.
    • (1999) J. Exp. Med , vol.189 , pp. 647-656
    • Centurion-Lara, A.1    Castro, C.2    Barrett, L.3    Cameron, C.4    Mostowfi, M.5    Van Voorhis, W.C.6    Lukehart, S.A.7
  • 8
    • 0027159295 scopus 로고
    • The localisation of treponemes and characterisation of the inflammatory infiltrate in skin biopsies from patients with primary or secondary syphilis, or early infectious yaws
    • Engelkens, H. J., F. J. ten Kate, J. Judanarso, V. D. Vuzevski, J. B. van Lier, J. C. Godscbalk, J. J. van der Sluis, and E. Stolz. 1993. The localisation of treponemes and characterisation of the inflammatory infiltrate in skin biopsies from patients with primary or secondary syphilis, or early infectious yaws. Genitourin. Med. 69:102-107.
    • (1993) Genitourin. Med , vol.69 , pp. 102-107
    • Engelkens, H.J.1    ten Kate, F.J.2    Judanarso, J.3    Vuzevski, V.D.4    van Lier, J.B.5    Godscbalk, J.C.6    van der Sluis, J.J.7    Stolz, E.8
  • 9
    • 0025997526 scopus 로고
    • Splenic T-lymphocyte functions during early syphilitic infection are complex
    • Fitzgerald, T. J., and M. A. Tomai. 1991. Splenic T-lymphocyte functions during early syphilitic infection are complex. Infect. Immun. 59:4180-4186.
    • (1991) Infect. Immun , vol.59 , pp. 4180-4186
    • Fitzgerald, T.J.1    Tomai, M.A.2
  • 11
    • 30544440752 scopus 로고    scopus 로고
    • Lymphocytes and MHC class II positive cells in the female rabbit reproductive tract before and after ovulation
    • Gu, W., P. Janssens, M. Holland, R. Seamark, and P. Kerr. 2005. Lymphocytes and MHC class II positive cells in the female rabbit reproductive tract before and after ovulation. Immunol. Cell Biol. 83:596-606.
    • (2005) Immunol. Cell Biol , vol.83 , pp. 596-606
    • Gu, W.1    Janssens, P.2    Holland, M.3    Seamark, R.4    Kerr, P.5
  • 12
    • 0027393538 scopus 로고
    • Generation and characterization of monoclonal antibodies against rabbit CD4, CD5 and CD11a antigens
    • Kotani, M., Y. Yamamura, T. Tamatani, F. Kitamura, and M. Miyasaka. 1993. Generation and characterization of monoclonal antibodies against rabbit CD4, CD5 and CD11a antigens. J. Immunol. Methods 157:241-252.
    • (1993) J. Immunol. Methods , vol.157 , pp. 241-252
    • Kotani, M.1    Yamamura, Y.2    Tamatani, T.3    Kitamura, F.4    Miyasaka, M.5
  • 13
    • 33644767982 scopus 로고    scopus 로고
    • TprK sequence diversity accumulates during infection of rabbits with Treponema pallidum subsp. pallidum Nichols strain
    • LaFond, R. E., A. Centurion-Lara, C. Godornes, W. C. Van Voorhis, and S. A. Lukehart. 2006. TprK sequence diversity accumulates during infection of rabbits with Treponema pallidum subsp. pallidum Nichols strain. Infect. Immun. 74:1896-1906.
    • (2006) Infect. Immun , vol.74 , pp. 1896-1906
    • LaFond, R.E.1    Centurion-Lara, A.2    Godornes, C.3    Van Voorhis, W.C.4    Lukehart, S.A.5
  • 14
    • 0015319170 scopus 로고
    • Serial ultrathin sectioning demonstrating the intracellularity of T. pallidum. An electron microscopic study
    • Lauderdale, V., and J. N. Goldman. 1972. Serial ultrathin sectioning demonstrating the intracellularity of T. pallidum. An electron microscopic study. Br. J. Vener. Dis. 48:87-96.
    • (1972) Br. J. Vener. Dis , vol.48 , pp. 87-96
    • Lauderdale, V.1    Goldman, J.N.2
  • 15
    • 0019990915 scopus 로고
    • Activation of macrophages by products of lymphocytes from normal and syphilitic rabbits
    • Lukehart, S. A. 1982. Activation of macrophages by products of lymphocytes from normal and syphilitic rabbits. Infect. Immun. 37:64-69.
    • (1982) Infect. Immun , vol.37 , pp. 64-69
    • Lukehart, S.A.1
  • 16
    • 0018884754 scopus 로고
    • Characterization of lymphocyte responsiveness in early experimental syphilis. II. Nature of cellular infiltration and Treponema pallidum distribution in testicular lesions
    • Lukehart, S. A., S. A. Baker-Zander, R. M. Lloyd, and S. Sell. 1980. Characterization of lymphocyte responsiveness in early experimental syphilis. II. Nature of cellular infiltration and Treponema pallidum distribution in testicular lesions. J. Immunol. 124:461-467.
    • (1980) J. Immunol , vol.124 , pp. 461-467
    • Lukehart, S.A.1    Baker-Zander, S.A.2    Lloyd, R.M.3    Sell, S.4
  • 17
    • 0022637928 scopus 로고
    • Characterization of the humoral immune response of the rabbit to antigens of Treponema pallidum after experimental infection and therapy
    • Lukehart, S. A., S. A. Baker-Zander, and S. Sell. 1986. Characterization of the humoral immune response of the rabbit to antigens of Treponema pallidum after experimental infection and therapy. Sex. Transm. Dis. 13:9-15.
    • (1986) Sex. Transm. Dis , vol.13 , pp. 9-15
    • Lukehart, S.A.1    Baker-Zander, S.A.2    Sell, S.3
  • 18
    • 0018141476 scopus 로고
    • Demonstration of the in vitro phagocytosis of Treponema pallidum by rabbit peritoneal macrophages
    • Lukehart, S. A., and J. N. Miller. 1978. Demonstration of the in vitro phagocytosis of Treponema pallidum by rabbit peritoneal macrophages. J. Immunol. 121:2014-2024.
    • (1978) J. Immunol , vol.121 , pp. 2014-2024
    • Lukehart, S.A.1    Miller, J.N.2
  • 19
    • 0032836886 scopus 로고    scopus 로고
    • Secondary syphilis in persons infected with and not infected with HlV-1: A comparative immunohistologic study
    • McBroom, R. L., A. R. Styles, M. J. Chiu, C. Clegg, C. J. Cockerell, and J. D. Radolf. 1999. Secondary syphilis in persons infected with and not infected with HlV-1: a comparative immunohistologic study. Am. J. Dermatopathol 21:432-441.
    • (1999) Am. J. Dermatopathol , vol.21 , pp. 432-441
    • McBroom, R.L.1    Styles, A.R.2    Chiu, M.J.3    Clegg, C.4    Cockerell, C.J.5    Radolf, J.D.6
  • 20
    • 9144225574 scopus 로고    scopus 로고
    • + T cells with prevention of severe destructive arthritis in Borrelia burgdorferi-vaccinated and challenged gamma interferon-deficient mice treated with anti-interleukin-17 antibody
    • + T cells with prevention of severe destructive arthritis in Borrelia burgdorferi-vaccinated and challenged gamma interferon-deficient mice treated with anti-interleukin-17 antibody. Clin. Diagn. Lab. Immunol. 11:1075-1084.
    • (2004) Clin. Diagn. Lab. Immunol , vol.11 , pp. 1075-1084
    • Nardelli, D.T.1    Burchill, M.A.2    England, D.M.3    Torrealba, J.4    Canister, S.M.5    Schell, R.F.6
  • 22
    • 0028940959 scopus 로고
    • Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytes/macrophages
    • Radolf, J. D., L. L. Arndt, D. R. Akins, L. L. Curetry, M. E. Levi, Y. Shen, L. S. Davis, and M. V. Norgard. 1995. Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytes/macrophages. J. Immunol. 154:2866-2877.
    • (1995) J. Immunol , vol.154 , pp. 2866-2877
    • Radolf, J.D.1    Arndt, L.L.2    Akins, D.R.3    Curetry, L.L.4    Levi, M.E.5    Shen, Y.6    Davis, L.S.7    Norgard, M.V.8
  • 23
    • 0020056725 scopus 로고
    • Experimental syphilitic orchitis in rabbits: Ultrastructural appearance of Treponema pallidum during phagocytosis and dissolution by macrophages in vivo
    • Sell, S., S. Baker-Zander, and H. C. Powell. 1982. Experimental syphilitic orchitis in rabbits: ultrastructural appearance of Treponema pallidum during phagocytosis and dissolution by macrophages in vivo. Lab. Investig. 46:355-364.
    • (1982) Lab. Investig , vol.46 , pp. 355-364
    • Sell, S.1    Baker-Zander, S.2    Powell, H.C.3
  • 24
    • 0019191430 scopus 로고
    • T-cell hyperplasia of lymphoid tissues of rabbits infected with Treponema pallidum: Evidence for a vigorous immune response
    • Sell, S., S. A. Baker-Zander, and R. M. Lloyd. 1980. T-cell hyperplasia of lymphoid tissues of rabbits infected with Treponema pallidum: evidence for a vigorous immune response. Sex. Transm. Dis. 7:74-84.
    • (1980) Sex. Transm. Dis , vol.7 , pp. 74-84
    • Sell, S.1    Baker-Zander, S.A.2    Lloyd, R.M.3
  • 25
    • 0019197938 scopus 로고
    • Host response to Treponema pallidum in intradermally-infected rabbits: Evidence for persistence of infection at local and distant sites
    • Sell, S., D. Gamboa, S. A. Baker-Zander, S. A. Lukehart, and J. N. Miller. 1980. Host response to Treponema pallidum in intradermally-infected rabbits: evidence for persistence of infection at local and distant sites. J. Investig. Dermatol. 75:470-475.
    • (1980) J. Investig. Dermatol , vol.75 , pp. 470-475
    • Sell, S.1    Gamboa, D.2    Baker-Zander, S.A.3    Lukehart, S.A.4    Miller, J.N.5
  • 26
    • 0015123112 scopus 로고
    • Intracellular location of Treponema pallidum (Nichols strain) in the rabbit testis
    • Sykes, J. A., and J. N. Miller. 1971. Intracellular location of Treponema pallidum (Nichols strain) in the rabbit testis. Infect. Immun. 4:307-314.
    • (1971) Infect. Immun , vol.4 , pp. 307-314
    • Sykes, J.A.1    Miller, J.N.2
  • 27
    • 0016032534 scopus 로고
    • Treponema pallidum within cells of a primary chancre from a human female
    • Sykes, J. A., J. N. Miller, and A. J. Kalan. 1974. Treponema pallidum within cells of a primary chancre from a human female. Br. J. Vener. Dis. 50:40-44.
    • (1974) Br. J. Vener. Dis , vol.50 , pp. 40-44
    • Sykes, J.A.1    Miller, J.N.2    Kalan, A.J.3
  • 28
    • 0024376407 scopus 로고
    • Macrophage-mediated suppression of conA-induced IL-2 production in spleen cells from syphilitic rabbits
    • Tomai, M. A., B. J. Elmquist, S. M. Warmka, and T. J. Fitzgerald. 1989. Macrophage-mediated suppression of conA-induced IL-2 production in spleen cells from syphilitic rabbits. J. Immunol. 143:309-314.
    • (1989) J. Immunol , vol.143 , pp. 309-314
    • Tomai, M.A.1    Elmquist, B.J.2    Warmka, S.M.3    Fitzgerald, T.J.4
  • 32
  • 33
    • 0021066839 scopus 로고
    • Studies of rabbit testes infected with Treponema pallidum. I. lmmunopathology
    • Wicher, K., V. Wicher, S. M. Nakeeb, and S. Dubiski. 1983. Studies of rabbit testes infected with Treponema pallidum. I. lmmunopathology. Br. J. Vener. Dis. 59:349-358.
    • (1983) Br. J. Vener. Dis , vol.59 , pp. 349-358
    • Wicher, K.1    Wicher, V.2    Nakeeb, S.M.3    Dubiski, S.4
  • 34
    • 0031751996 scopus 로고    scopus 로고
    • Cytokine gene expression in skin of susceptible guinea-pig infected with Treponema pallidum
    • Wicher, V., A. M. Scarozza, A. I. Ramsingh, and K. Wicher. 1998. Cytokine gene expression in skin of susceptible guinea-pig infected with Treponema pallidum. Immunology 95:242-247.
    • (1998) Immunology , vol.95 , pp. 242-247
    • Wicher, V.1    Scarozza, A.M.2    Ramsingh, A.I.3    Wicher, K.4
  • 35
    • 0021059844 scopus 로고
    • Studies of rabbit testes infected with Treponema pallidum. II. Local synthesis of antibodies
    • Wicher, V., and K. Wicher. 1983. Studies of rabbit testes infected with Treponema pallidum. II. Local synthesis of antibodies. Br. J. Vener. Dis. 59:359-363.
    • (1983) Br. J. Vener. Dis , vol.59 , pp. 359-363
    • Wicher, V.1    Wicher, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.