Diffusion-weighted MRI in the body: Applications and challenges in oncology

American Journal of Roentgenology

Volumn 188, Issue 6, 2007, Pages 1622-1635

  Koh, Dow Mu ^a,b   Collins, David J ^a,b  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b ROYAL MARSDEN HOSPITAL   (United Kingdom)

Author keywords

Abdominal imaging; Cancer; Diffusion weighted imaging; MRI; Oncologic imaging; Pelvic imaging; Whole body imaging

Indexed keywords

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; DIFFUSION WEIGHTED IMAGING; FEMALE; HUMAN; IMAGE ANALYSIS; MALE; MONITORING; ONCOLOGY; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; TECHNIQUE; TREATMENT RESPONSE; WHOLE BODY IMAGING;

ADULT; DIFFUSION MAGNETIC RESONANCE IMAGING; HUMANS; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MALE; MEDICAL ONCOLOGY; NEOPLASMS; PROGNOSIS; WHOLE BODY IMAGING;

EID: 34249874331     PISSN: 0361803X     EISSN: None     Source Type: Journal    
DOI: 10.2214/AJR.06.1403     Document Type: Article

References (79)

1. Yoshikawa K, Nakata Y, Yamada K, Nakagawa M. Early pathological changes in the parkinsonian brain demonstrated by diffusion tensor MRI. J Neurol Neurosurg Psychiatry 2004; 75:481-484
2. Eastwood JD, Lev MH, Wintermark M, et al. Correlation of early dynamic CT perfusion imaging with whole-brain MR diffusion and perfusion imaging in acute hemispheric stroke. Am J Neurorad iol 2003; 24:1869-1875
3. Le Bihan D. Molecular diffusion nuclear magnetic resonance imaging. Magn Reson Q 1991; 7:1-30
4. Le Bihan D, Breton E, Lallemand D, Aubin ML, Vignaud J, Laval-Jeantet M. Separation of diffusion and perfusion in intravoxel incoherent motion MR imaging. Radiology 1988; 168:497-505
5. Thoeny HC, De Keyzer F, Vandecaveye V, et al. Effect of vascular targeting agent in rat tumor model: dynamic contrast-enhanced versus diffusion-weighted MR imaging. Radiology 2005; 237:492-499
6. Guo Y, Cai YQ, Cai ZL, et al. Differentiation of clinically benign and malignant breast lesions using diffusion-weighted imaging. J Magn Reson Imaging 2002; 16:172-178
7. Gauvain KM, McKinstry RC, Mukherjee P, et al. Evaluating pediatric brain tumor cellularity with diffusion-tensor imaging. AJR 2001; 177:449-454
8. Sugahara T, Korogi Y, Kochi M, et al. Usefulness of diffusion-weighted MRI with echo-planar technique in the evaluation of cellularity in gliomas. J Magn Reson Imaging 1999; 9:53-60
9. Lang P, Wendland MF, Saeed M, et al. Osteogenic sarcoma: noninvasive in vivo assessment of tumor necrosis with diffusion-weighted MR imaging. Radiology 1998; 206:227-235
10. Stejskal EO, Tanner JE. Spin diffusion measurements: spin-echo in the presence of a time dependent field gradient. J Chem Phys 1965; 42:288-292
11. Neil JJ. Measurement of water motion (apparent diffusion) in biological systems. Concepts Magn Reson 1997; 9:385-401
12. Inoue T, Ogasawara K, Beppu T, Ogawa A, Kabasawa H. Diffusion tensor imaging for preoperative evaluation of tumor grade in gliomas. Clin Neurol Neurosurg 2005; 107:174-180
13. Ries M, Jones RA, Basseau F, Moonen CT, Grenier N. Diffusion tensor MRI of the human kidney. J Magn Reson Imaging 2001; 14:42-49
14. Taouli B, Martin AJ, Qayyum A, et al. Parallel imaging and diffusion tensor imaging for diffusion-weighted MRI of the liver: preliminary experience in healthy volunteers. AJR 2004; 183:677-680
15. Sinha S, Sinha U. In vivo diffusion tensor imaging of the human prostate. Magn Reson Med 2004; 52:530-537
16. Bammer R. Basic principles of diffusion-weighted imaging. Eur J Radiol 2003; 45:169-184
17. Okada Y, Ohtomo K, Kiryu S, Sasaki Y. Breath-hold T2-weighted MRI of hepatic tumors: value of echo planar imaging with diffusion-sensitizing gradient. J Comput Assist Tomogr 1998; 22:364-371
18. Squillaci E, Manenti G, Di Stefano F, Miano R, Strigari L, Simonetti G. Diffusion-weighted MR imaging in the evaluation of renal tumours. J Exp Clin Cancer Res 2004; 23:39-45
19. Abe Y, Yamashita Y, Tang Y, Namimoto T, Takahashi M. Calculation of T2 relaxation time from ultrafast single shot sequences for differentiation of liver tumors: comparison of echo-planar, HASTE, and spin-echo sequences. Radiat Med 2000; 18:7-14
20. Yamashita Y, Tang Y, Takahashi M. Ultrafast MR imaging of the abdomen: echo planar imaging and diffusion-weighted imaging. J Magn Reson Imaging 1998; 8:367-374
21. Ito K, Mitchell DG, Matsunaga N. MR imaging of the liver: techniques and clinical applications. Eur J Radiol 1999; 32:2-14
22. Park SW, Lee JH, Ehara S, et al. Single shot fast spin echo diffusion-weighted MR imaging of the spine: is it useful in differentiating malignant metastatic tumor infiltration from benign fracture edema? Clin Imaging 2004; 28:102-108
23. Takahara T, Imai Y, Yamashita T, Yasuda S, Nasu S, Van Cauteren M. Diffusion weighted whole body imaging with background body signal suppression (DWIBS): technical improvement using free breathing, STIR and high resolution 3D display. Radiat Med 2004; 22:275-282
24. Moteki T, Sekine T. Echo planar MR imaging of the liver: comparison of images with and without motion probing gradients. J Magn Reson Imaging 2004; 19:82-90
25. Nasu K, Kuroki Y, Nawano S, et al. Hepatic metastases: diffusion-weighted sensitivity-encoding versus SPIO-enhanced MR imaging. Radiology 2006; 239:122-130
26. Koh DM, Brown G, Riddell A, Scurr E, Collins DJ, Husband JE. Colorectal liver metastases: evaluation using MnDPDP enhanced MR imaging and breath-hold single-shot echo-planar diffusion-weighted MR imaging. Eur Radiol Suppl 2005; 15S:B144
27. Brockstedt S, Borg M, Geijer B, et al. Triggering in quantitative diffusion imaging with single-shot EPI. Acta Radiol 1999; 40:263-269
28. Murtz P, Flacke S, Traber F, van den Brink JS, Gieseke J, Schild HH. Abdomen: diffusion-weighted MR imaging with pulse-triggered single-shot sequences. Radiology 2002; 224:258-264
29. Provenzale JM, Mukundan S, Barboriak DP. Diffusion-weighted and perfusion MR imaging for brain tumor characterization and assessment of treatment response. Radiology 2006; 239:632-649
30. Koh DM, Scurr E, Collins DJ, et al. Colorectal hepatic metastases: quantitative measurements using single-shot echo-planar diffusion-weighted MR imaging. Eur Radiol 2006; 16:1898-1905
31. Taouli B, Vilgrain V, Dumont E, Daire JL, Fan B, Menu Y. Evaluation of liver diffusion isotropy and characterization of focal hepatic lesions with two single-shot echo-planar MR imaging sequences: prospective study in 66 patients. Radiology 2003; 226:71-78
32. Kim T, Murakami T, Takahashi S, Hori M, Tsuda K, Nakamura H. Diffusion-weighted single-shot echoplanar MR imaging for liver disease. AJR 1999; 173:393-398
33. Chan JH, Tsui EY, Luk SH, et al. Diffusion-weighted MR imaging of the liver: distinguishing hepatic abscess from cystic or necrotic tumor. Abdom Imaging 2001; 26:161-165
34. Koh DM, Scurr E, Collins DJ, et al. Colorectal hepatic metastases: quantitative measurements using single-shot echo-planar diffusion-weighted MR imaging. Eur Radiol 2006; 16:1898-1905
35. Yamada I, Aung W, Himeno Y, Nakagawa T, Shibuya H. Diffusion coefficients in abdominal organs and hepatic lesions: evaluation with intravoxel incoherent motion echo-planar MR imaging. Radiology 1999; 210:617-623
36. Cova M, Squillaci E, Stacul F, et al. Diffusion-weighted MRI in the evaluation of renal lesions: preliminary results. Br J Radiol 2004; 77:851-857
37. Fukuda Y, Ohashi I, Hanafusa K, et al. Anisotropic diffusion in kidney: apparent diffusion coefficient measurements for clinical use. J Magn Reson Im aging 2000; 11:156-160
38. Rubesova E, Grell AS, De Maertelaer V, Metens T, Chao SL, Lemort M. Quantitative diffusion imaging in breast cancer: a clinical prospective study. J Magn Reson Imaging 2006; 24:319-324
39. Sinha S, Lucas-Quesada FA, Sinha U, DeBruhl N, Bassett LW. In vivo diffusion-weighted MRI of the breast: potential for lesion characterization. J Magn Reson Imaging 2002; 15:693-704
40. Dietrich O, Raya JG, Sommer J, Deimling M, Reiser MF, Baur-Melnyk A. A comparative evaluation of a RARE-based single-shot pulse sequence for diffusion-weighted MRI of musculoskeletal soft-tissue tumors. Eur Radiol 2005; 15:772-783
41. Ichikawa T, Erturk SM, Motosugi U, et al. High-B-value diffusion-weighted MRI in colorectal cancer. AJR 2006; 187:181-184
42. Irie H, Honda H, Kuroiwa T, et al. Measurement of the apparent diffusion coefficient in intraductal mucin-producing tumor of the pancreas by diffusion-weighted echo-planar MR imaging. Abdom Imaging 2002; 27:82-87
43. Moteki T, Ishizaka H. Diffusion-weighted EPI of cystic ovarian lesions: evaluation of cystic contents using apparent diffusion coefficients. J Magn Reson Imaging 2000; 12:1014-1019
44. Issa B. In vivo measurement of the apparent diffusion coefficient in normal and malignant prostatic tissues using echo-planar imaging. J Magn Reson Imaging 2002; 16:196-200
45. Gibbs P, Tozer DJ, Liney GP, Turnbull LW. Comparison of quantitative T2 mapping and diffusion-weighted imaging in the normal and pathologic prostate. Magn Reson Med 2001; 46:1054-1058
46. Junqian G, Humphrey PA, Kibel AS, Narra VR, Song S-K. Exclusion of the false positive identification of prostate cancer using diffusion anisotropy. In: Proceedings of the International Society of Magnetic Resonance in Medicine meeting, Seattle, WA. Berkeley, CA: International Society for Magnetic Resonance in Medicine, 2006:174
47. Baur A, Huber A, Durr HR, et al. Differentiation of benign osteoporotic and neoplastic vertebral compression fractures with a diffusion-weighted, steady-state free precession sequence [in German]. Rofo 2002; 174:70-75
48. Bhugaloo AA, Abdullah BJJ, Siow YS, Ng KH. Diffusion-weighted MR imaging in acute vertebral compression fractures: differentiation between malignant and benign causes. Biomed Imaging Interv J 2006; 2:e12
49. Chan JH, Peh WC, Tsui EY, et al. Acute vertebral body compression fractures: discrimination between benign and malignant causes using apparent diffusion coefficients. Br J Radiol 2002; 75:207-214
50. Byun WM, Shin SO, Chang Y, Lee SJ, Finsterbusch J, Frahm J. Diffusion-weighted MR imaging of metastatic disease of the spine: assessment of response to therapy. Am J Neuroradiol 2002; 23:906-912
51. Spuentrup E, Buccker A, Adam G, van Vaals JJ, Guenther RW. Diffusion-weighted MR imaging for differentiation of benign fracture edema and tumor infiltration of the vertebral body. AJR 2001; 176:351-358
52. Castillo M, Arbelaez A, Smith JK, Fisher LL. Diffusion-weighted MR imaging offers no advantage over routine noncontrast MR imaging in the detection of vertebral metastases. Am J Neuroradiol 2000; 21:948-953
53. Herneth AM, Philipp MO, Naude J, et al. Vertebral metastases: assessment with apparent diffusion coefficient. Radiology 2002; 225:889-894
54. Zhou XJ, Leeds NE, McKinnon GC, Kumar AJ. Characterization of benign and metastatic vertebral compression fractures with quantitative diffusion MR imaging. Am J Neuroradiol 102; 23:165-170
55. Bammer R, Herneth AM, Maier SE, et al. Line scan diffusion imaging of the spine. Am J Neuroradiol 2003; 24:5-12
56. Maeda M, Sakuma H, Maier SE, Takeda K. Quantitative assessment of diffusion abnormalities in benign and malignant vertebral compression fractures by line scan diffusion-weighted imaging. AJR 2003; 181:1203-1209
57. Eastwood JD, Vollmer RT, Provenzale JM. Diffusion-weighted imaging in a patient with vertebral and epidural abscesses. Am J Neuroradiol 2002; 23:496-498
58. Vandecaveye V, de Keyzer F, Vander Poorten V, et al. Evaluation of the larynx for tumour recurrence by diffusion-weighted MRI after radiotherapy: initial experience in four cases. Br J Radiol 2006; 79:681-687
59. Moffat BA, Chenevert TL, Lawrence TS, et al. Functional diffusion map: a noninvasive MRI biomarker for early stratification of clinical brain tumor response. Proc Natl Acad Sci U S A 2005; 102:5524-5529
60. Moffat BA, Hall DE, Slojanovska J, et al. Diffusion imaging for evaluation of tumor therapies in preclinical animal models. MAGMA 2004; 17:249-259
61. van Rijswijk CS, Kunz P, Hogendoorn PC, Taminiau AH, Doombos J, Bloem JL. Diffusion-weighted MRI in the characterization of soft-tissue tumors. J Magn Reson Imaging 2002; 15:302-307
62. Thoeny HC, De Keyzer F, Chen F, et al. Diffusion-weighted MR imaging in monitoring the effect of a vascular targeting agent on rhabdomyosarcoma in rats. Radiology 2005; 234:756-764
63. Mardor Y, Roth Y, Ochershvilli A, et al. Pretreatment prediction of brain tumors' response to radiation therapy using high b-value diffusion-weighted MRI. Neoplasia 2004; 6:136-142
64. Chen CY, Li CW, Kuo YT, et al. Early response of hepatocellular carcinoma to transcatheter arterial chemoembolization: choline levels and MR diffusion constants-initial experience. Radiology 2006; 239:448-456
65. Chenevert TL, McKeeverPE, Ross BD. Monitoring early response of experimental brain tumors to therapy using diffusion magnetic resonance imaging. Clin Cancer Res 1997; 3:1457-1466
66. Einarsdottir H, Karlsson M, Wejde J, Bauer HC. Diffusion-weighted MRI of soft tissue tumours. Eur Radiol 2004; 14:959-963
67. Koh DM, Scurr E, Collins DJ, et al. Predicting response of colorectal hepatic metastases: the value of pre-treatment apparent diffusion coefficients. AJR (in press)
68. DeVries AF, Kremser C, Hein PA, et al. Tumor microcirculation and diffusion predict therapy outcome for primary rectal carcinoma. Int J Radiat Oncol Biol Phys 2003; 56:958-965
69. Dzik-Jurasz A, Domenig C, George M, et al. Diffusion MRI for prediction of response of rectal cancer to chemoradiation. Lancet 2002; 360:307-308
70. Oh J, Henry RG, Pirzkall A, et al. Survival analysis in patients with glioblastoma multiforme: predictive value of choline-to-N-acetylaspartate index, apparent diffusion coefficient, and relative cerebral blood volume. J Magn Reson Imaging 2004;19:546-554
71. Mardor Y, Pfeifer R, Spiegelmann R, el al. Early detection of response to radiation therapy in patients with brain malignancies using conventional and high b-value diffusion-weighted magnetic resonance imaging. J Clin Oncol 2003 ; 21:1094-1100
72. Theilmann RJ, Borders R, Trouard TP, et al. Changes in water mobility measured by diffusion MRI predict response of metastatic breast cancer to chemotherapy. Neoplasia 2004; 6:831-837
73. Galons JP, Altbach MI, Paine-Murriela GD, Taylor CW, Gillies RJ. Early increases in breast tumor xenograft water mobility in response to paclitaxel therapy detected by non-invasive diffusion magnetic resonance imaging. Neoplasia 1999; 1:113-117
74. Jennings D, Hatton BN, Guo J, et al. Early response of prostate carcinoma xenografts to docetaxel chemotherapy monitored with diffusion MRI. Neoplasia 2002; 4:255-262
75. Jordan BF, Runquist M, Raghunand N, et al. Dynamic contrast-enhanced and diffusion MRI show rapid and dramatic changes in tumor microenvironment in response to inhibition of HIF-1 alpha using PX-478. Neoplasia 2005; 7:475-485
76. Lemaire L, Howe FA, Rodrigues LM, Griffiths JR. Assessment of induced rat mammary tumour response to chemotherapy using the apparent diffusion coefficient of tissue water as determined by diffusion-weighted IH-NMR spectroscopy in vivo. MAGNA 1999; 8:20-26
77. Roth Y, Tichler T, Kostenich G, et al. High-b-value diffusion-weighted MR imaging for pretreatment prediction and early monitoring of tumor response to therapy in mice. Radiology 2004; 232:685-692
78. Schepkin VD, Chenevert TL, Kuszpit K, et al. Sodium and proton diffusion MRI as biomarkers for early therapeutic response in subcutaneous tumors. Magn Reson Imaging 2006; 24:273-278
79. Stegman LD, Rehemtulla A, Hamstra DA, et al. Diffusion MRI detects early events in the response of a glioma model to the yeast cytosine deaminase gene therapy strategy. Gene Ther 2000; 7:1005-1010