Superantigen natural affinity maturation revealed by the crystal structure of staphylococcal enterotoxin G and its binding to T-cell receptor Vβ8.2

Proteins: Structure, Function and Genetics

Volumn 68, Issue 1, 2007, Pages 389-402

  Fernández, Marisa M ^a,b   Bhattacharya, Suparna ^b   De Marzi, Mauricio C ^a   Brown, Patrick H ^b,c   Kerzic, Melissa ^b   Schuck, Peter ^c   Mariuzza, Roy A ^b   Malchiodi, Emilio L ^a,b  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Bacterial superantigen; MHC class II; SEG; Staphylococcus aureus; T cell receptor

Indexed keywords

STAPHYLOCOCCUS ENTEROTOXIN; STAPHYLOCOCCUS ENTEROTOXIN G; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; ISOTHERMAL TITRATION CALORIMETRY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN STRUCTURE; RECEPTOR BINDING; STAPHYLOCOCCUS AUREUS; STRUCTURE ANALYSIS; TOXIN ANALYSIS; WILD TYPE; X RAY CRYSTALLOGRAPHY;

ANIMALS; CALORIMETRY; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; ENTEROTOXINS; HLA-DR1 ANTIGEN; MICE; MODELS, MOLECULAR; MUTAGENESIS; PROTEIN BINDING; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; STAPHYLOCOCCUS AUREUS; SUPERANTIGENS; T-LYMPHOCYTES; ULTRACENTRIFUGATION;

BACTERIA (MICROORGANISMS); MURINAE; STAPHYLOCOCCUS AUREUS;

EID: 34249869859     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21388     Document Type: Article

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