Mapping the landscape of the lymphocytic choriomeningitis virus stable signal peptide reveals novel functional domains

Journal of Virology

Volumn 81, Issue 11, 2007, Pages 5649-5657

  Saunders, April A ^a   Ting, Joey P C ^a   Meisner, Jeffrey ^b   Neuman, Benjamin W ^a,c   Perez, Mar ^a   De La Torre, Juan Carlos ^a   Buchmeier, Michael J ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF READING   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; MUTANT PROTEIN; PROTEINASE; SIGNAL PEPTIDE; VIRUS GLYCOPROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARENAVIRUS; ARTICLE; CELL FUSION; CELL MEMBRANE TRANSPORT; CELL SURFACE; CONTROLLED STUDY; DELETION MUTANT; ENDOPLASMIC RETICULUM; GENE TARGETING; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN TRANSPORT; VIROGENESIS; VIRUS PARTICLE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; CELL LINE, TUMOR; HUMANS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MEMBRANE GLYCOPROTEINS; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE MAPPING; PROTEIN INTERACTION MAPPING; PROTEIN PRECURSORS; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, TERTIARY; SEQUENCE DELETION; VIRAL PROTEINS;

LYMPHOCYTIC CHORIOMENINGITIS VIRUS; NEW WORLD ARENAVIRUSES;

EID: 34249826090     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02759-06     Document Type: Article

References (29)

1. Abramoff, M. D., P. J. Magelhaes, and S. J. Ram. 2004. Image processing with ImageJ. Biophotonics Int. 11:36-42.
2. Agnihothram, S. S., J. York, and J. H. Nunberg. 2006. Role of the stable signal peptide and cytoplasmic domain of G2 in regulating intracellular transport of the Junin virus envelope glycoprotein complex. J. Virol. 80:5189-5198.
3. Beyer, W. R., D. Popplau, W. Garten, D. von Laer, and O. Lenz. 2003. Endoproteolytic processing of the lymphocytic choriomeningitis virus glycoprotein by the subtilase SKI-1/S1P. J. Virol. 77:2866-2872.
4. Bieniasz, P. D. 2006. Late budding domains and host proteins in enveloped virus release. Virology 344:55-63.
5. Buchmeier, M. J., J. H. Elder, and M. B. Oldstone. 1978. Protein structure of lymphocytic choriomeningitis virus: identification of the virus structural and cell associated polypeptides. Virology 89:133-145.
6. Burns, J. W., and M. J. Buchmeier. 1991. Protein-protein interactions in lymphocytic choriomeningitis virus. Virology 183:620-629.
7. Burns, J. W., and M. J. Buchmeier. 1993. Glycoproteins of the arenaviruses, p. 17-35. In M. Salvato (ed.), The Arenaviridae. Plenum Press, New York, NY.
8. Clamp, M., J. Cuff, S. M. Searle, and G. J. Barton. 2004. The Jalview Java alignment editor. Bioinformatics 20:426-427.
9. Di Simone, C, and M. J. Buchmeier. 1995. Kinetics and pH dependence of acid-induced structural changes in the lymphocytic choriomeningitis virus glycoprotein complex. Virology 209:3-9.
10. Di Simone, C, M. A. Zandonatti, and M. J. Buchmeier. 1994. Acidic pH triggers LCMV membrane fusion activity and conformational change in the glycoprotein spike. Virology 198:455-465.
11. Eichler, R., O. Lenz, T. Strecker, and W. Garten. 2003. Signal peptide of Lassa virus glycoprotein GP-C exhibits an unusual length. FEBS Lett. 538:203-206.
12. Eichler, R., O. Lenz, T. Strecker, M. Eickmann, H. D. Klenk, and W. Garten. 2003. Identification of Lassa virus glycoprotein signal peptide as a transacting maturation factor. EMBO Rep. 4:1084-1088.
13. Eichler, R., O. Lenz, T. Strecker, M. Eickmann, H. D. Klenk, and W. Garten. 2004. Lassa virus glycoprotein signal peptide displays a novel topology with an extended endoplasmic reticulum luminal region. J. Biol. Chem. 279:12293-12299.
14. Eng, F. J., O. Varlamov, and L. D. Fricker. 1999. Sequences within the cytoplasmic domain of gpl80/carboxypeptidase D mediate localization to the trans-Golgi network. Mol. Biol. Cell 10:35-46.
15. Freed, E. O. 2002. Viral late domains. J. Virol. 76:4679-4687.
16. Froeschke, M., M. Basler, M. Groettrup, and B. Dobberstein. 2003. Long-lived signal peptide of lymphocytic choriomeningitis virus glycoprotein pGP-C. J. Biol. Chem. 278:41914-41920.
17. Gallagher, T. M., C. Escarmis, and M. J. Buchmeier. 1991. Alteration of the pH dependence of coronavirus-induced cell fusion: effect of mutations in the spike glycoprotein. J. Virol. 65:1916-1928.
18. Higy, M., S. Gander, and M. Spiess. 2005. Probing the environment of signal-anchor sequences during topogenesis in the endoplasmic reticulum. Biochemistry 44:2039-2047.
19. Lee, K. J., M. Perez, D. D. Pinschewer, and J. C. de la Torre. 2002. Identification of the lymphocytic choriomeningitis virus (LCMV) proteins required to rescue LCMV RNA analogs into LCMV-like particles. J. Virol. 76:6393-6397.
20. Ohno, H., J. Stewart, M. C. Fournier, H. Bosshart, I. Rhee, S. Miyatake, T. Saito, A. Gallusser, T. Kirchhausen, and J. S. Bonifacino. 1995. Interaction of tyrosine-based sorting signals with clathrin-associated proteins. Science 269:1872-1875.
21. Perez, M., R. C. Craven, and J. C. de la Torre. 2003. The small RING finger protein Z drives arenavirus budding: implications for antiviral strategies. Proc. Natl. Acad. Sci. USA 100:12978-12983.
22. Schmitt, A. P., G. P. Leser, E. Morita, W. I. Sundquist, and R. A. Lamb. 2005. Evidence for a new viral late-domain core sequence, FPIV, necessary for budding of a paramyxovirus. J. Virol. 79:2988-2997.
23. von Heijne, G. 1998. Life and death of a signal peptide. Nature 396:111,113.
24. von Heijne, G. 1985. Signal sequences. The limits of variation. J. Mol. Biol. 184:99-105.
25. Weber, E. L., and M. J. Buchmeier. 1988. Fine mapping of an antigenic site conserved among arenaviruses. Virology 164:30-38.
26. Wright, K. E., R. C. Spiro, J. W. Burns, and M. J. Buchmeier. 1990. Post-translational processing of the glycoproteins of lymphocytic choriomeningitis virus. Virology 177:175-183.
27. York, J., V. Romanowski, M. Lu, and J. H. Nunberg. 2004. The signal peptide of the Junin arenavirus envelope glycoprotein is myristoylated and forms an essential subunit of the mature G1-G2 complex. J. Virol. 78:10783-10792.
28. York, J., and J. H. Nunberg. 2006. Role of the stable signal peptide of Junin arenavirus envelope glycoprotein in pH-dependent membrane fusion. J. Virol. 80:7775-7780.
29. York, J., and J. H. Nunberg. 2007. Distinct requirements for signal peptidase processing and function in the stable signal peptide subunit of the Junin virus envelope glycoprotein. Virology 359:72-81.