Characteristics of vulvar squamous cell carcinoma in Japanese women

Pathology International

Volumn 57, Issue 6, 2007, Pages 322-327

  Osakabe, Mitsumasa ^a   Hayashi, Masahiro ^a   Katayama, Yousei ^b   Emura, Iwao ^c   Nemoto, Keiichi ^d   Umezu, Hajime ^e   Saitoh, Ken ^f   Motoyama, Teiichi ^a  

^a YAMAGATA UNIVERSITY   (Japan)

^b Hachinohe Municipal Hospital   (Japan)

^c NAGAOKA RED CROSS HOSPITAL   (Japan)

^d NIIGATA CANCER CENTER HOSPITAL   (Japan)

^e NIIGATA UNIVERSITY MEDICAL AND DENTAL HOSPITAL   (Japan)

^f AKITA RED CROSS HOSPITAL   (Japan)

Author keywords

Human papillomavirus; p16; p53; Squamous cell carcinoma; Vulva

Indexed keywords

PROTEIN P16INK4A; PROTEIN P53; TUMOR MARKER;

ADULT; AGED; ARTICLE; BASAL CELL CARCINOMA; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE MUTATION; GENETIC DISORDER; HISTOLOGY; HUMAN; HUMAN TISSUE; JAPAN; KERATINIZATION; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; VERRUCOUS CARCINOMA; VULVA CARCINOMA; WART VIRUS;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA, NEOPLASM; DNA, VIRAL; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; JAPAN; LOSS OF HETEROZYGOSITY; MIDDLE AGED; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53; VULVAR NEOPLASMS;

EID: 34249825231     PISSN: 13205463     EISSN: 14401827     Source Type: Journal    
DOI: 10.1111/j.1440-1827.2007.02103.x     Document Type: Article

References (26)

1. Toki T, Kurman RJ, Park JS et al. Probable nonpapillomavirus etiology of squamous cell carcinoma of the vulva in older women: A clinicopathologic study using in situ hybridization and polymerase chain reaction. Int J Gynecol Pathol 1991 10 : 107 25.
2. Kurman RJ, Toki T, Schiffman MH. Basaloid and warty carcinomas of the vulva. Distinctive types of squamous cell carcinoma frequently associated with human papillomaviruses. Am J Surg Pathol 1993 17 : 133 45.
3. Hørding U, Junge J, Daugaard S et al. Vulvar squamous cell carcinoma and papillomaviruses: Indications for two different etiologies. Gynecol Oncol 1994 52 : 241 6.
4. Monk BJ, Burger RA, Lin F et al. Prognostic significance of human papillomavirus DNA in vulvar carcinoma. Obstet Gynecol 1995 85 : 709 15.
5. Trimble CL, Hildesheim A, Brinton LA et al. Heterogeneous etiology of squamous carcinoma of the vulva. Obstet Gynecol 1996 87 : 59 64.
6. Nagano H, Yoshikawa H, Kawana T et al. Association of multiple human papillomavirus types with vulvar neoplasias. J Obstet Gynaecol Res 1996 22 : 1 8.
7. Koyamatsu Y, Yokoyama M, Nakao Y et al. A comparative analysis of human papillomavirus types 16 and 18 and expression of p53 gene and Ki-67 in cervical, vaginal, and vulvar carcinomas. Gynecol Oncol 2003 90 : 547 51.
8. Akashi K, Nagasaka T, Nakashim N et al. Squamous cell carcinoma of the vulva and adjacent lesions treated at Nagoya University Hospital from 1965 to 1997. Nagoya J Med Sci 2001 64 : 109 21.
9. Schiffman MH, Moreno V, Kurman R et al. Prevalence of human papillomavirus in cervical cancer: A worldwide perspective. J Natl Cancer Inst 1995 87 : 796 802.
10. Scheffner M, Werness BA, Huibregtse JM. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 1990 63 : 1129 36.
11. Dyson N, Howley PM, Munger K et al. The human papillomavirus 16, E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 1989 243 : 934 9.
12. Tsuda H, Hashiguchi Y, Nishimura S et al. Relationship between HPV typing and abnormality of G1 cell cycle regulators in cervical neoplasm. Gynecol Oncol 2003 91 : 476 85.
13. Tavassoli FA, Devilee P, eds. World Health Organization Classification of tumors. Pathology and Genetics of Tumors of Breast and Female Genital Organs. Lyon : IARC Press, 2003.
14. Yoshikawa H, Kawana T, Kitagawa K et al. Detection and typing of multiple genital human papillomaviruses by DNA amplification with consensus primers. Jpn J Cancer Res 1991 82 : 524 31.
15. Jin Z, Ogata S, Tamura G et al. Carcinosarcomas (malignant mullerian mixed tumors) of the uterus and ovary: A genetic study with special reference to histogenesis. Int J Gynecol Pathol 2003 22 : 368 73.
16. Kern SE, Fearon ER, Tersmette KW et al. Clinical and pathological associations with allelic loss in colorectal carcinoma. JAMA 1989 261 : 3099 103.
17. Kagie MJ, Kenter GG, Tollenaar RA et al. p53 protein overexpression is common and independent of human papillomavirus infection in squamous cell carcinoma of the vulva. Cancer 1997 80 : 1228 33.
18. Lee YY, Wilczynski SP, Chumakov A et al. Carcinoma of the vulva: HPV and p53 mutations. Oncogene 1994 9 : 1655 9.
19. Milde-Langosch K, Albrecht K, Joram S et al. Presence and persistence of HPV infection and p53 mutation in cancer of the cervix uteri and the vulva. Int J Cancer 1995 63 : 639 45.
20. Kim YT, Thomas NF, Kessis TD et al. p53 mutations and clonality in vulvar carcinomas and squamous hyperplasias: Evidence suggesting that squamous hyperplasias do not serve as direct precursors of human papillomavirus-negative vulvar carcinomas. Hum Pathol 1996 27 : 389 95.
21. Klaes R, Friedrich T, Spitkovsky D et al. Overexpression of p16 (INK4A) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri. Int J Cancer 2001 92 : 276 84.
22. Klaes R, Benner A, Friedrich T et al. p16INK4a immunohistochemistry improves interobserver agreement in the diagnosis of cervical intraepithelial neoplasia. Am J Surg Pathol 2002 26 : 1389 99.
23. Negri G, Egarter-Vigl E, Kasal A et al. p16INK4a is a useful marker for the diagnosis of adenocarcinoma of the cervix uteri and its precursors: An immunohistochemical study with immunocytochemical correlations. Am J Surg Pathol 2003 27 : 187 93.
24. Santos M, Montagut C, Mellado B et al. Immunohistochemical staining for p16 and p53 in premalignant and malignant epithe-lial lesions of the vulva. Int J Gynecol Pathol 2004 23 : 206 14.
25. Riethdorf S, Neffen EF, Cviko A et al. p16INK4A expression as biomarker for HPV 16-related vulvar neoplasias. Hum Pathol 2004 35 : 1477 83.
26. Lin ZH, Shen XH, Jin Z et al. Human papillomavirus genotyping by oligonucleotide microarray and p16 expression in uterine cervical intraepithelial neoplasm and in invasive carcinoma in Korean women. Pathol Int 2005 55 : 491 6.