Images in allergy and immunology: Role of eosinophils in airway remodeling

Journal of Allergy and Clinical Immunology

Volumn 119, Issue 6, 2007, Pages 1563-1566

  Foley, Susan C ^a   Préfontaine, David ^a   Hamid, Qutayba ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; GELATINASE B; INTERLEUKIN 11; INTERLEUKIN 17; INTERLEUKIN 25; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; ASTHMA; AUTOCRINE EFFECT; CYTOKINE PRODUCTION; DISEASE SEVERITY; EOSINOPHIL; FORCED EXPIRATORY VOLUME; HUMAN; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LUNG LAVAGE; PARACRINE SIGNALING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY TRACT INFLAMMATION;

BRONCHI; EOSINOPHILS; HUMANS; RESPIRATORY MUCOSA;

EID: 34249797579     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2007.03.040     Document Type: Article

References (9)

1. Wenzel S.E., Schwartz L.B., Langmack E.L., Halliday J.L., Trudeau J.B., Gibbs R.L., et al. Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am J Respir Crit Care Med 160 (1999) 1001-1008
2. Minshall E.M., Leung D.Y.M., Martin R.J., Song Y.L., Cameron L., Ernst P., et al. Eosinophil-associated TGF-β1 mRNA expression and airways fibrosis in bronchial asthma. Am J Respir Cell Mol Biol 17 (1997) 326-333
3. Minshall E., Chakir J., Laviolette M., Molet S., Zhu Z., Olivenstein R., et al. IL-11 expression is increased in severe asthma: association with epithelial cells and eosinophils. J Allergy Clin Immunol 105 (2000) 232-238
4. Aceves S.S., Newbury R.O., Dohill R., Bastian J.F., and Broids D.H. Esophageal remodeling in pediatric eosinophilic esophagitis. J Allergy Clin Immunol 119 (2007) 206-212
5. Flood-Page P., Menzies-Gow A., Phipps S., Ying S., Wangoo A., Ludwig M.S., et al. Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J Clin Invest 112 (2003) 1029-1036
6. Phipps S., Flood-Page P., Menzies-Gow A., Ong Y.E., and Kay A.B. Intravenous anti-IL-5 monoclonal antibody reduces eosinophils and tenascin deposition in allergen-challenged human atopic skin. J Invest Dermatol 122 (2004) 1406-1412
7. Hoshino M., Nakamura Y., Sim J., Shimojo J., and Isogai S. Bronchial subepithelial fibrosis and expression of matrix metalloproteinase-9 in asthmatic airway inflammation. J Allergy Clin Immunol 102 (1998) 783-788
8. Wiehler S., Cuvelier S.L., Chakrabarti S., and Patela K.D. p38 MAP kinase regulates rapid matrix metalloproteinase-9 release from eosinophils. Biochem Biophys Res Commun 315 (2004) 463-470
9. Leung S.Y., Eynott P., Nath P., and Chung K.F. Effects of ciclesonide and fluticasone propionate on allergen-induced inflammation and remodeling features. J Allergy Clin Immunol 115 (2005) 989-996