Lack of effect of oral selenite on p53 associated gene expression during TL01 therapy of psoriasis patients

Photodermatology Photoimmunology and Photomedicine

Volumn 23, Issue 2-3, 2007, Pages 98-100

  Desilva, Bernadette ^a   Beckett, Geoffrey J ^a   McLean, Steven ^a   Arthur, John R ^b   Hunter, John A A ^a   Norval, Mary ^a   McKenzie, Roddie C ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

Langerhans cells; Phototherapy; Sodium selenite; Sunburn cells; UV induced proteins

Indexed keywords

FAS ANTIGEN; GUANOSINE; PLACEBO; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SODIUM SELENITE; T6 ANTIGEN;

ADULT; ARTICLE; CELL COUNT; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; FEMALE; GENE EXPRESSION; GENETIC CODE; HUMAN; HUMAN CELL; HUMAN TISSUE; LANGERHANS CELL; MALE; OUTCOME ASSESSMENT; PHOTOTHERAPY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PSORIASIS; RADIATION INJURY; RANDOMIZED CONTROLLED TRIAL; SKIN BIOPSY; SKIN CELL; SKIN INJURY; TREATMENT DURATION; TUMOR SUPPRESSOR GENE; ULTRAVIOLET A RADIATION; WHOLE BODY RADIATION;

ADMINISTRATION, ORAL; ADULT; COMBINED MODALITY THERAPY; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MIDDLE AGED; PSORIASIS; SEVERITY OF ILLNESS INDEX; SODIUM SELENITE; TREATMENT OUTCOME; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS; ULTRAVIOLET THERAPY;

EID: 34249796970     PISSN: 09054383     EISSN: 16000781     Source Type: Journal    
DOI: 10.1111/j.1600-0781.2007.00277.x     Document Type: Article

References (5)

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4. McKenzie RC, Arthur JR, Beckett GJ. Selenium and the regulation of cell signalling, growth and survival: Molecular and mechanistic aspects. Antioxid Redox Signal 2002; 4: 339-351.
5. Traynor NJ, McKenzie RC, Beckett GJ, Gibbs NK. Selenomethionine inhibits ultraviolet radiation-induced p53 transactivation. Photodermatol Photoimmunol Photomed 2006; 22: 297.