Angiotensin I converting enzyme gene polymorphism and exercise trainability in elderly women: An electrocardiological approach

Journal of Sports Science and Medicine

Volumn 6, Issue 2, 2007, Pages 220-226

  Tobina, Takuro ^a,b,d   Kiyonaga, Akira ^b   Akagi, Yuko ^b   Mori, Yukari ^b   Ishii, Kojiro ^a   Chiba, Hitoshi ^c   Shindo, Munehiro ^b   Tanaka, Hiroaki ^b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b FUKUOKA UNIVERSITY   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

^d NONE   (Japan)

Author keywords

Electrophysiology; Exercise; Genes

Indexed keywords

EID: 34249793238     PISSN: None     EISSN: 13032968     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Ayabe, M., Yahiro, T., Mori, Y., Takayama, K., Tobina, T., Higuchi, H., Ishii, K., Sakuma, I., Yoshitake, Y., Miyazaki, H., Kiyonaga, A., Shindo, M. and Tanaka, H. (2003) Simple assessment of lactate threshold by means of the bench stepping in older population. International Journal of Sport and Health Science 1, 207-215.
2. Bidoggia, H., Maciel, J.P., Capalozza, N., Mosca, S., Blaksley, E.J., Valverde, E., Bertran, G., Arini, P., Biagetti, M.O., Quinteiro, R.A. (2000) Sex differences on the electrocardiographic pattern of cardiac repolarization: possible role of testosterone. American Heart Journal 140, 678-683.
3. Boccalandro, F., Velasco, A., Thomas, C., Richards, B., Radovancevic, B. (2003) Relations among heart failure severity, left ventricular loading conditions, and repolarization length in advanced heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. American Journal of Cardiology 92, 544-547.
4. Cambien, F., Poirier, O., Lecerf, L., Evans, A., Cambou, J.P., Arveiler, D., Luc, G., Bard, J.M., Bara, L., Ricard, S. (1992) Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 359, 641-4.
5. Cohen, N.D., Roussel, A.J., Lumsden, J.H., Cohen, A.C., Grift, E., Lewis, C. (1993) Alterations of fluid and electrolyte balance in thoroughbred racehorses following strenuous exercise during training. Canadian Journal of Veterinary Research 57, 9-13.
6. De Bruyne, M.C., Hoes, A.W., Kors, J.A., Hofman, A., Van Bemmel, J.H., Grobbee, D.E. (1999) Prolonged QT interval predicts cardiac and all-cause mortality in the elderly. The Rotterdam Study. European Heart Journal 20, 278-284.
7. DeLong, M., Logan, J.L., Yong, K.C., Lien, Y.H. (2005) Renin-angiotensin blockade reduces serum free testosterone in middle-aged men on haemodialysis and correlates with erythropoietin resistance. Nephrology Dialysis Transplantation 20, 585-590.
8. Echt, D.S., Black, J.N., Barbey, J.T., Coxe, D.R., Cato, E. (1989) Evaluation of antiarrhythmic drugs on defibrillation energy requirements in dogs. Sodium channel block and action potential prolongation. Circulation 79, 1106-1117.
9. Farquharson, C.A., Struthers, A.D. (2002) Increasing plasma potassium with amiloride shortens the QT interval and reduces ventricular extrasystoles but does not change endothelial function or heart rate variability in chronic heart failure. Heart 88, 475-480.
10. Hacihanefioglu, B., Somunkiran, A., Mahmutoglu, I., Sercelik, A., Toptani, S., Kervancioglu, E. (2002) Effect of hypertension therapy with the angiotensin-converting enzyme inhibitor lisinopril on hyperandrogenism in women with polycystic ovary syndrome. Fertility and Sterility 77, 526-528.
11. Hakkinen, K., Pakarinen, A. (1994) Serum hormones and strength development during strength training in middle-aged and elderly males and females. Acta Physiologica Scandinavica 150, 211-219.
12. Hart, G. Exercise-induced cardiac hypertrophy: a substrate for sudden death in athletes? (2003) Exercise-induced cardiac hypertrophy: a substrate for sudden death in athletes? Experimental Physiology 88, 639-644.
13. Hernandez, D., de la Rosa, A., Barragan, A., Barrios, Y., Salido, E., Torres, A., Martin, B., Laynez, I., Duque, A., De Vera, A., Lorenzo, V., Gonzalez, A. (2003) The ACE/DD genotype is associated with the extent of exercise-induced left ventricular growth in endurance athletes. Journal of the American College of Cardiology 42, 527-532.
14. Kritchevsky, S.B., Nicklas, B.J., Visser, M., Simonsick, E.M., Newman, A.B., Harris, T.B., Lange, E.M., Penninx, B.W., Goodpaster, B.H., Satterfield, S., Colbert, L.H., Rubin, S.M., Pahor, M. (2005) Angiotensin-converting enzyme insertion/deletion genotype, exercise, and physical decline. Journal of the American Medical Association 294, 691-698.
15. Koshida, H., Takeda, R., Miyamori, I. (1998) Lisinopril decreases plasma free testosterone in male hypertensive patients and increases sex hormone binding globulin in female hypertensive patients. Hypertension Research 21, 279-282.
16. Lindpaintner, K., Pfeffer, M.A., Kreutz, R., Stampfer, M.J., Grodstein, F., LaMotte, F., Buring, J., Hennekens, C.H. (1995) A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. The New England Journal of Medicine 332, 706-711.
17. Montgomery, H.E., Clarkson, P., Dollery, C.M., Prasad, K., Losi, M.A., Hemingway, H., Statters, D., Jubb, M., Girvain, M., Varnava, A., World, M., Deanfield, J., Talmud, P., McEwan, J.R., McKenna, W.J., Humphries, S. (1997) Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training. Circulation 96, 741-747.
18. Montgomery, H.E., Marshall, R., Hemingway, H., Myerson, S., Clarkson, P., Dollery, C., Hayward, M., Holliman, D.E., Jubb, M., World, M., Thomas, E.L., Brynes, A.E., Saeed N, Barnard M, Bell JD, Prasad K, Rayson M, Talmud PJ, Humphries SE. (1998) Human gene for physical performance. Nature 393, 221-222.
19. Mori, Y., Ayabe, M., Yahiro, T., Tobina, T., Kiyonaga, A., Shindo, M., Yamada, T., Tanaka, H. (2006) The effect of home-based bench step exercise on anaerobic capacity, lower extremity strength and static balance in older adults. International Journal of Sport and Health Science 4, 570-576.
20. Myerson, S., Hemingway, H., Budget, R., Martin, J., Humphries, S., Montgomery, H. (1999) Human angiotensin I-converting enzyme gene and endurance performance. Journal of Applied Physiology 87, 1313-6.
21. Nazarov, I.B., Woods, D.R., Montgomery, H.E., Shneider, O.V., Kazakov, V.I., Tomilin, N.V., Rogozkin, V.A. (2001) The angiotensin converting enzyme I/D polymorphism in Russian athletes. European Journal of Human Genetics 9, 797-801.
22. Onder, G., Penninx, B.W., Balkrishnan, R., Fried, L.P., Chaves, P.H., Williamson, J., Carter, C., Di Bari, M., Guralnik, J.M., Pahor, M. (2002) Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: an observational study. Lancet 359, 926-930.
23. Rigat, B., Hubert, C., Alhenc-Gelas, F., Cambien, F., Corvol, P., Soubrier, F. (1990) An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. Journal of Clinical Investigation 86, 1343-1346.
24. Sato, A., Suzuki, Y., Shibata, H., Saruta, T. (2000) Plasma aldosterone concentrations are not related to the degree of angiotensin-converting enzyme inhibition in essential hypertension. Hypertension Research 23, 25-31.
25. Schachter, F., Faure-Delanef, L., Guenot, F., Rouger, H., Froguel, P., Lesueur-Ginot, L., Cohen, D. (1994) Genetic associations with human longevity at the APOE and ACE loci. Nature Genetics 6, 29-32.
26. Schuit, A.J., Dekker, J.M., de Vegt, F., Verheij, T.C., Rijneke, R.D., Schouten, E.G. (1998) Effect of physical training on QTc interval in elderly people. Journal of Electrocardiology 31, 111-116.
27. Stajer, D., Mozina, H., Noc, M., Rode, P. (1993) Correlation between QTc interval duration and left ventricular systolic dysfunction in patients with acute myocardial infarction. Journal of Electrocardiology 26, 333-340.
28. Tobina, T., Ayabe, M., Yoshitake, Y., Kimura, Y., Miyazaki, H., Ishii, K., Zhang, B., Saku, K., Shindo, M., Kiyonaga, A., Tanaka, H. (2006) Relationship between angiotensin converting enzyme gene I/D polymorphism and muscle strength in elderly. International Journal of Sport and Health Science 4, 465-471.
29. Vescovo, G., Dalla Libera, L., Serafini, F., Leprotti, C., Facchin, L., Volterrani, M., Ceconi, C., Ambrosio, G.B. (1998) Improved exercise tolerance after losartan and enalapril in heart failure: correlation with changes in skeletal muscle myosin heavy chain composition. Circulation 98, 1742-1749.
30. Willems, J.L., Arnaud, P., van Bemmel, J.H., Bourdillon, P.J., Brohet, C., Dalla Volta, S., Andersen, J.D., Degani, R., Denis, B., Demeester, M. (1985) Assessment of the performance of electrocardiographic computer programs with the use of a reference data base. Circulation 71, 523-534.
31. Wolfarth, B., Bray, M.S., Hagberg, J.M., Perusse, L., Rauramaa, R., Rivera, M.A., Roth, S.M., Rankinen, T., Bouchard, C. (2005) The human gene map for performance and health-related fitness phenotypes: the 2004 update. Medicine and Science in Sports and Exercise 37, 881-903.