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1
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27144488370
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Recent reviews include: a
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Recent reviews include: (a) Suzuki, A. Chem. Commun. 2005, 38, 4759.
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(2005)
Chem. Commun
, vol.38
, pp. 4759
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Suzuki, A.1
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2
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11244296859
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2nd ed, de Meijere, A, Diederich, F, Eds, Wiley-VCH: Weinheim
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(b) Miyaura, N. In Metal-Catalyzed Cross-Coupling Reactions, 2nd ed., Vol. 1: de Meijere, A.; Diederich, F., Eds.; Wiley-VCH: Weinheim, 2004, 41-123.
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(2004)
Metal-Catalyzed Cross-Coupling Reactions
, vol.1
, pp. 41-123
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Miyaura, N.1
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3
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0036589259
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(c) Hassan, J.; Sévignon, M.; Gozzi, C.; Schulz, E.; Lemaire, M. Chem. Rev. 2002, 102, 1359.
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(2002)
Chem. Rev
, vol.102
, pp. 1359
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Hassan, J.1
Sévignon, M.2
Gozzi, C.3
Schulz, E.4
Lemaire, M.5
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4
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0037175592
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(d) Kotha, S.; Lahiri, K.; Kashinath, D. Tetrahedron 2002, 58, 9633.
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(2002)
Tetrahedron
, vol.58
, pp. 9633
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Kotha, S.1
Lahiri, K.2
Kashinath, D.3
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6
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0038637139
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For example: a
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For example: (a) Murray, T. K.; Whalley, K.; Robinson, C. S.; Ward, M. A.; Hicks, C. A.; Lodge, D.; Vandergriff, J. L.; Baumbarger, P.; Siuda, E.; Gates, M.; Ogden, A. M.; Skolnick, P.; Zimmerman, D. M.; Nisenbaum, E. S.; Bleakman, D.; O'Neill, M. J. J. Pharmacol. Exp. Ther. 2003, 306, 752.
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(2003)
J. Pharmacol. Exp. Ther
, vol.306
, pp. 752
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Murray, T.K.1
Whalley, K.2
Robinson, C.S.3
Ward, M.A.4
Hicks, C.A.5
Lodge, D.6
Vandergriff, J.L.7
Baumbarger, P.8
Siuda, E.9
Gates, M.10
Ogden, A.M.11
Skolnick, P.12
Zimmerman, D.M.13
Nisenbaum, E.S.14
Bleakman, D.15
O'Neill, M.J.16
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7
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0037424719
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(b) Faghih, R.; Dwight, W.; Pan, J. B.; Fox, G. B.; Krueger, K. M.; Esbenshade, T. A.; McVey, J. M.; Marsh, K.; Bennani, Y. L.; Hancock, A. A. Bioorg. Med. Chem. Lett. 2003, 13, 1325.
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(2003)
Bioorg. Med. Chem. Lett
, vol.13
, pp. 1325
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Faghih, R.1
Dwight, W.2
Pan, J.B.3
Fox, G.B.4
Krueger, K.M.5
Esbenshade, T.A.6
McVey, J.M.7
Marsh, K.8
Bennani, Y.L.9
Hancock, A.A.10
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8
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0034618541
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(c) Hajduk, P. J.; Bures, M.; Praetgaard, J.; Fesik, S. W. J. Med. Chem. 2000, 43, 3443.
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(2000)
J. Med. Chem
, vol.43
, pp. 3443
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Hajduk, P.J.1
Bures, M.2
Praetgaard, J.3
Fesik, S.W.4
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9
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33745472389
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(a) O'Brien, C. J.; Kantchev, E. A. B.; Hadei, N.; Valente, C.; Chass, G. A.; Lough, A.; Hopkinson, A. C.; Organ, M. G. Chem. Eur. J. 2006, 12, 4743.
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(2006)
Chem. Eur. J
, vol.12
, pp. 4743
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O'Brien, C.J.1
Kantchev, E.A.B.2
Hadei, N.3
Valente, C.4
Chass, G.A.5
Lough, A.6
Hopkinson, A.C.7
Organ, M.G.8
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12
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3042708394
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(a) Okamoto, K.; Akiyama, R.; Kobayashi, S. Org. Lett. 2004, 6, 1987.
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(1987)
Org. Lett
, vol.2004
, pp. 6
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Okamoto, K.1
Akiyama, R.2
Kobayashi, S.3
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16
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34249816897
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FibreCat 1001 is available from Johnson Matthey.
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(e) FibreCat 1001 is available from Johnson Matthey.
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17
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34249815934
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4 is available from Biotage AB.
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4 is available from Biotage AB.
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18
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0037161861
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(a) Ramarao, C.; Ley, S. V.; Smith, S. C.; Shirley, I. M.; DeAlmeida, N. Chem. Commun. 2002, 1132.
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(2002)
Chem. Commun
, pp. 1132
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Ramarao, C.1
Ley, S.V.2
Smith, S.C.3
Shirley, I.M.4
DeAlmeida, N.5
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19
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0037161724
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(b) Ley, S. V.; Ramarao, C.; Gordon, R. S.; Holmes, A. B.; Morrison, A. J.; McConvey, I.; Shirley, I. M.; Smith, S. C.; Smith, M. D. Chem. Commun. 2002, 1134.
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(2002)
Chem. Commun
, pp. 1134
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Ley, S.V.1
Ramarao, C.2
Gordon, R.S.3
Holmes, A.B.4
Morrison, A.J.5
McConvey, I.6
Shirley, I.M.7
Smith, S.C.8
Smith, M.D.9
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20
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34249794665
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2EnCat™ is available from Sigma Aldrich.
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2EnCat™ is available from Sigma Aldrich.
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21
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34249805210
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2EnCat™ (5 mol%, based on palladium content). The reaction mixture was stirred at 85 °C for 18 h.
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2EnCat™ (5 mol%, based on palladium content). The reaction mixture was stirred at 85 °C for 18 h.
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22
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34249793782
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MP-Carbonate was obtained from Sigma-Aldrich with a reported loading of 2.5-3.5 mmol/g.
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MP-Carbonate was obtained from Sigma-Aldrich with a reported loading of 2.5-3.5 mmol/g.
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23
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0344666674
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Lan, P.; Berta, D.; Porco, J. A.; South, M. S.; Parlow, J. J. J. Org. Chem. 2003, 68, 9678.
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(2003)
J. Org. Chem
, vol.68
, pp. 9678
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Lan, P.1
Berta, D.2
Porco, J.A.3
South, M.S.4
Parlow, J.J.5
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24
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0033581550
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(a) Hall, D. G.; Tailor, J.; Gravel, M. Angew. Chem. Int. Ed. 1999, 38, 3064.
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(1999)
Angew. Chem. Int. Ed
, vol.38
, pp. 3064
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Hall, D.G.1
Tailor, J.2
Gravel, M.3
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25
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34249808920
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WO 9742230
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(b) Bolton, G. L.; Booth, R. J.; Cresswell, M. W.; Hodges, J. C.; Warmus, J. S.; Wilson, M. W.; Kennedy, R. M. WO 9742230, 1997.
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(1997)
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Bolton, G.L.1
Booth, R.J.2
Cresswell, M.W.3
Hodges, J.C.4
Warmus, J.S.5
Wilson, M.W.6
Kennedy, R.M.7
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26
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34249826428
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N,N-Diethanol-aminomethyl polystyrene (PS-DEAM) was obtained from Biotage AB.
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(c) N,N-Diethanol-aminomethyl polystyrene (PS-DEAM) was obtained from Biotage AB.
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27
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34249814124
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Although the water present could be removed using anhydrous molecular sieves, a more reliable and pragmatic procedure proved to be co-evaporation prior to redissolution in DMF
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Although the water present could be removed using anhydrous molecular sieves, a more reliable and pragmatic procedure proved to be co-evaporation prior to redissolution in DMF.
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31
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0035813244
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(d) Lidströmm, P.; Tierney, J.; Wathey, B.; Westman, J. Tetrahedron 2001, 57, 9225.
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(2001)
Tetrahedron
, vol.57
, pp. 9225
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Lidströmm, P.1
Tierney, J.2
Wathey, B.3
Westman, J.4
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33
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34249823447
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Microwave reactions were performed using an Emrys® synthesiser available from Biotage AB
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(f) Microwave reactions were performed using an Emrys® synthesiser available from Biotage AB.
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34
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34249809214
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Microwave temperatures were measured externally to the reactor vial using the IR sensor fitted to the Emrys® synthesiser. It is extremely unlikely that these values accurately reflect the significantly higher localised temperatures attained at the catalyst metal surface under microwave irradiation
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Microwave temperatures were measured externally to the reactor vial using the IR sensor fitted to the Emrys® synthesiser. It is extremely unlikely that these values accurately reflect the significantly higher localised temperatures attained at the catalyst metal surface under microwave irradiation.
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35
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34249786664
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Palladium residue levels were determined using inductively coupled plasma optical emission spectroscopy performed on 4′-methoxy-4- methylbiphenyl(3) for both thermal and microwave reactions and indicated residual palladium levels in 3 corresponding to Pd leaching from Pd(OAc)2EnCat™ to be 2.1% and 1.7, respectively
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2EnCat™ to be 2.1% and 1.7%, respectively.
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36
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34249794074
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High-speed vortexing was performed using a DESYRE®-MIX vortexer, available from Zinsser Analytic GmbH
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High-speed vortexing was performed using a DESYRE®-MIX vortexer, available from Zinsser Analytic GmbH.
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37
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0008300963
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Tamura, Y.; Chun, M. W.; Inoue, K.; Minamikawa, J. Synthesis 1978, 822.
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(1978)
Synthesis
, pp. 822
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Tamura, Y.1
Chun, M.W.2
Inoue, K.3
Minamikawa, J.4
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