Rational design of vector and antibiotic peptides using solid-state NMR

Mini-Reviews in Medicinal Chemistry

Volumn 7, Issue 5, 2007, Pages 491-497

  Mason, A J ^a,c   Bechinger, B ^a   Kichler, A ^b  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b GÉNÉTHON   (France)

^c UNIVERSITÉ LOUIS PASTEUR   (France)

Author keywords

Antibiotic peptides; Gene transfer; Histidine; LAH4; Pleurocidin; Solid state NMR

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; ANTIBIOTIC AGENT; LYSYLLYSYLALANYLLEUCYLLEUCYLALANYLHISTIDYLALANYLLEUCYLALANYLHISTIDYLLEUCYLALANYLLEUCYLLEUCYLALANYLLEUCYLHISTIDYLLEUCYLALANYLLEUCYLHISTIDYLLEUCYLLYSYLLYSYLALANINE; LYSYLLYSYLALANYLLEUCYLLEUCYLALANYLHISTIDYLALANYLLEUCYLHISTIDYLLEUCYLLEUCYLALANYLLEUCYLLEUCYLALANYLLEUCYLHISTIDYLLEUCYLALANYLHISTIDYLALANYLLEUCYLLYSYLLYSYLALANINE; LYSYLLYSYLALANYLLEUCYLLEUCYLALANYLLEUCYLALANYLLEUCYLHISTIDYLHISTIDYLEUCYLALANYLLEUCYLLEUCYLALANYLLEUCYLHISTIDYLLEUCYLALANYLHISTIDYLALANYLLEUCYLLYSYLLYSYLALANINE; LYSYLLYSYLALANYLLEUCYLLEUCYLALANYLLEUCYLALANYLLEUCYLHISTIDYLHISTIDYLLEUCYLALANYLHISTIDYLLEUCYLALANYLLEUCYLHISTIDYLLEUCYLALANYLLEUCYLALANYLLEUCYLLYSYLLYSYLALANINE; LYSYLLYSYLALANYLLEUCYLLEUCYLHISTIDYLLEUCYLALANYLLEUCYLALANYLLEUCYLLEUCYLALANYLLEUCYLHISTIDYLALANYLHISTIDYLALANYLLEUCYLALANYLLEUCYLHISTIDYLLEUCYLLSYLLYSYLALANINE; MEMBRANE LIPID; NUCLEIC ACID; PLASMID DNA; PLEUROCIDIN; POLYETHYLENEIMINE; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL LABELING; DEUTERON NUCLEAR MAGNETIC RESONANCE; DNA VECTOR; DRUG CONFORMATION; DRUG MECHANISM; DRUG SELECTIVITY; DRUG STRUCTURE; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; MEMBRANE BINDING; MEMBRANE TRANSPORT; MOLECULAR INTERACTION; NITROGEN NUCLEAR MAGNETIC RESONANCE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NUCLEAR MAGNETIC RESONANCE; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PROTEIN ANALYSIS; PROTEIN LIPID INTERACTION; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL MEMBRANE; DNA; DRUG DESIGN; GENETIC VECTORS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34249786560     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/138955707780619563     Document Type: Article

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