메뉴 건너뛰기




Volumn 7, Issue SUPPL. 4, 2007, Pages

Current treatment strategies for multiple myeloma

Author keywords

Allogeneic stem cell transplantation; Proteasome inhibitors; Tandem transplantation

Indexed keywords

ACICLOVIR; ALPHA INTERFERON; BORTEZOMIB; DEXAMETHASONE; DOXORUBICIN; ERYTHROPOIETIN; FLUDARABINE; HEAT SHOCK PROTEIN 90 INHIBITOR; HISTONE DEACETYLASE INHIBITOR; LENALIDOMIDE; LOW MOLECULAR WEIGHT HEPARIN; MELPHALAN; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PREDNISONE; THALIDOMIDE; VALACICLOVIR; VASCULOTROPIN INHIBITOR; VINCRISTINE; WARFARIN;

EID: 34249781147     PISSN: 15579190     EISSN: None     Source Type: Journal    
DOI: 10.3816/CLM.2007.s.014     Document Type: Article
Times cited : (7)

References (52)
  • 2
    • 0038509089 scopus 로고    scopus 로고
    • Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: A report of the International Myeloma Working Group
    • International Myeloma Working Group
    • International Myeloma Working Group. Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group. Br J Haematol 2003; 121:749-757.
    • (2003) Br J Haematol , vol.121 , pp. 749-757
  • 3
    • 18244428600 scopus 로고    scopus 로고
    • Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose thetapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant
    • Blade J, Samson D, Reece D, et al. Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose thetapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant. Br J Haematol 1998; 102:1115-1123.
    • (1998) Br J Haematol , vol.102 , pp. 1115-1123
    • Blade, J.1    Samson, D.2    Reece, D.3
  • 4
    • 0035353192 scopus 로고    scopus 로고
    • Serum free light-chain measurements for identifying and monitoring patients with non-secretory multiple myeloma
    • Drayson M, Tang L, Drew R, et al. Serum free light-chain measurements for identifying and monitoring patients with non-secretory multiple myeloma. Blood 2001; 97:2900-2902.
    • (2001) Blood , vol.97 , pp. 2900-2902
    • Drayson, M.1    Tang, L.2    Drew, R.3
  • 5
    • 0037208595 scopus 로고    scopus 로고
    • Thalidomide alone or with dexamethasone for previously untreated multiple myeloma
    • Weber D, Rankin K, Gavino M, et al. Thalidomide alone or with dexamethasone for previously untreated multiple myeloma. J Clin Oncol 2003; 21:16-19.
    • (2003) J Clin Oncol , vol.21 , pp. 16-19
    • Weber, D.1    Rankin, K.2    Gavino, M.3
  • 6
    • 33644831033 scopus 로고    scopus 로고
    • Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: A clinical trial coordinated by the Eastern Cooperative Oncology Group
    • Rajkumar SV, Blood E, Vesole D, et al. Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: a clinical trial coordinated by the Eastern Cooperative Oncology Group. J Clin Oncol 2006; 24:431-436.
    • (2006) J Clin Oncol , vol.24 , pp. 431-436
    • Rajkumar, S.V.1    Blood, E.2    Vesole, D.3
  • 7
    • 33644898842 scopus 로고    scopus 로고
    • A systematic review of phase-II trials of thalidomide monotherapy in patients with relapsed or refractory multiple myeloma
    • Glasmacher A, Hahn C, Hoffmann F, et al. A systematic review of phase-II trials of thalidomide monotherapy in patients with relapsed or refractory multiple myeloma. Br J Haematol 2006; 132:584-593.
    • (2006) Br J Haematol , vol.132 , pp. 584-593
    • Glasmacher, A.1    Hahn, C.2    Hoffmann, F.3
  • 8
    • 33750625445 scopus 로고    scopus 로고
    • Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma
    • Fisher RI, Bernstein SH, Kahl BS, et al. Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma. J Clin Oncol 2006; 24:4867-4874.
    • (2006) J Clin Oncol , vol.24 , pp. 4867-4874
    • Fisher, R.I.1    Bernstein, S.H.2    Kahl, B.S.3
  • 9
    • 20044369803 scopus 로고    scopus 로고
    • Antitumor activity of bortezomib (PS-341; Velcade) in a phase II study of patients with pteviously untreated or treated Waldenstrom's macroglobulinemia (WM)
    • Abstract
    • Chen CI, White D, Kouroukis CT, et al. Antitumor activity of bortezomib (PS-341; Velcade) in a phase II study of patients with pteviously untreated or treated Waldenstrom's macroglobulinemia (WM). Blood 2004; 104:896a (Abstract #3278).
    • (2004) Blood , vol.104 , Issue.3278
    • Chen, C.I.1    White, D.2    Kouroukis, C.T.3
  • 10
    • 20044396543 scopus 로고    scopus 로고
    • Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma
    • Goy A, Younes A, McLaughlin P, et al. Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma. J Clin Oncol 2005; 23:667-675.
    • (2005) J Clin Oncol , vol.23 , pp. 667-675
    • Goy, A.1    Younes, A.2    McLaughlin, P.3
  • 11
    • 20444433230 scopus 로고    scopus 로고
    • Bortezomib or high-dose dexamethasone for relapsed multiple myeloma
    • Richardson PG, Sonneveld R Schuster MW, et al. Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N Engl J Med 2005; 352:2487-2498.
    • (2005) N Engl J Med , vol.352 , pp. 2487-2498
    • Richardson, P.G.1    Sonneveld, R.2    Schuster, M.W.3
  • 12
    • 21344469223 scopus 로고    scopus 로고
    • Bortezomib therapy alone and in combination with dexamethasone for previously untreated symptomatic multiple myeloma
    • Jagannath S, Durie BG, Wolf, J, et al. Bortezomib therapy alone and in combination with dexamethasone for previously untreated symptomatic multiple myeloma. Br J Haematol 2005; 129:776-783.
    • (2005) Br J Haematol , vol.129 , pp. 776-783
    • Jagannath, S.1    Durie, B.G.2    Wolf, J.3
  • 13
    • 21344435052 scopus 로고    scopus 로고
    • PAD combination therapy (PS-341/bortezomib, doxorubicin and dexamethasone) for previously untreated patients with multiple myeloma
    • Oakervee HE, Popat R, Curry N, et al. PAD combination therapy (PS-341/bortezomib, doxorubicin and dexamethasone) for previously untreated patients with multiple myeloma. Br J Haematol 2005; 129:755-762.
    • (2005) Br J Haematol , vol.129 , pp. 755-762
    • Oakervee, H.E.1    Popat, R.2    Curry, N.3
  • 14
    • 33745765108 scopus 로고    scopus 로고
    • Reduced dose PAD combination therapy (PS-341/ bortezomib, adriamycin and dexamethasone) for previously untreated patients with multiple myeloma
    • Abstract
    • Popat R, Oakervee H, Curry N, et al. Reduced dose PAD combination therapy (PS-341/ bortezomib, adriamycin and dexamethasone) for previously untreated patients with multiple myeloma. Blood 2005; 106:717a (Abstract #2554).
    • (2005) Blood , vol.106 , Issue.2554
    • Popat, R.1    Oakervee, H.2    Curry, N.3
  • 15
    • 34249810772 scopus 로고    scopus 로고
    • Bortezomib in combination with thalidomide-dexamethasone for previously untreated multiple myeloma
    • In press
    • Wang LM, Giralt S, Delasalle K, et al. Bortezomib in combination with thalidomide-dexamethasone for previously untreated multiple myeloma. Haematology. In press.
    • Haematology
    • Wang, L.M.1    Giralt, S.2    Delasalle, K.3
  • 16
    • 33748287079 scopus 로고    scopus 로고
    • Bortezomib plus melphalan and prednisone in elderly untreated patients with multiple myeloma: Results of a multicenter phase 1/2 study
    • Mateos MV, Hernández JM, Hernández MT. Bortezomib plus melphalan and prednisone in elderly untreated patients with multiple myeloma: results of a multicenter phase 1/2 study. Blood 2006; 108:2165-2172.
    • (2006) Blood , vol.108 , pp. 2165-2172
    • Mateos, M.V.1    Hernández, J.M.2    Hernández, M.T.3
  • 17
    • 33750607347 scopus 로고    scopus 로고
    • A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma
    • Richardson PG, Blood E, Mitsiades CS, et al. A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma. Blood 2006; 108:3458-3464.
    • (2006) Blood , vol.108 , pp. 3458-3464
    • Richardson, P.G.1    Blood, E.2    Mitsiades, C.S.3
  • 18
    • 34249826762 scopus 로고    scopus 로고
    • Weber DM, Chen C, Niesvizky R, et al. Lenalidomide plus high-dose dexamethasone provides improved overall survival compared to high-dose dexamethasone alone for relapsed or refractory multiple myeloma (MM): results of a North American phase III study (MM-009). J Clin Oncol 2006; 24(18 suppl):427s (Abstract #7521).
    • Weber DM, Chen C, Niesvizky R, et al. Lenalidomide plus high-dose dexamethasone provides improved overall survival compared to high-dose dexamethasone alone for relapsed or refractory multiple myeloma (MM): results of a North American phase III study (MM-009). J Clin Oncol 2006; 24(18 suppl):427s (Abstract #7521).
  • 19
    • 27744492561 scopus 로고    scopus 로고
    • Combination therapy with lenalidomide plus dexamethasone (rev/dex) for newly diagnosed myeloma
    • Rajkumar SV, Hayman SR, Lacy MQ, et al. Combination therapy with lenalidomide plus dexamethasone (rev/dex) for newly diagnosed myeloma. Blood 2005; 106:4050-4053.
    • (2005) Blood , vol.106 , pp. 4050-4053
    • Rajkumar, S.V.1    Hayman, S.R.2    Lacy, M.Q.3
  • 20
    • 33646494190 scopus 로고    scopus 로고
    • Lenalidomide and venous thrombosis in multiple myeloma
    • Knighr R, DeLap RJ, Zeldis JB. Lenalidomide and venous thrombosis in multiple myeloma. N Engl J Med 2006; 354:2079-2080.
    • (2006) N Engl J Med , vol.354 , pp. 2079-2080
    • Knighr, R.1    DeLap, R.J.2    Zeldis, J.B.3
  • 21
    • 4444298973 scopus 로고    scopus 로고
    • VTD regimen comprising velcade (V) + thalidomide (T) and added DEX (D) for non-responders to V + T effects a 57% PR rate among 56 patients with myeloma (M) relapsing after autologous transplant
    • Abstract
    • Zangari M, Barlogie B, Jacobson J, et al. VTD regimen comprising velcade (V) + thalidomide (T) and added DEX (D) for non-responders to V + T effects a 57% PR rate among 56 patients with myeloma (M) relapsing after autologous transplant. Blood 2003; 102:236a (Abstract #830).
    • (2003) Blood , vol.102 , Issue.830
    • Zangari, M.1    Barlogie, B.2    Jacobson, J.3
  • 22
    • 33645662389 scopus 로고    scopus 로고
    • Rapid control of previously untreated multiple myeloma with bortezomib-thalidomide-dexamethasone followed by early intensive therapy
    • Abstract
    • Wang LM, Delasalle K, Giralt S, et al. Rapid control of previously untreated multiple myeloma with bortezomib-thalidomide-dexamethasone followed by early intensive therapy. Blood 2005; 106:231a (Abstract #784).
    • (2005) Blood , vol.106 , Issue.784
    • Wang, L.M.1    Delasalle, K.2    Giralt, S.3
  • 23
    • 33744803947 scopus 로고    scopus 로고
    • A phase 1 trial of lenalidomide (Revlimid®) with bortezomib (Velcade®) in relapsed and refractory multiple myeloma
    • Abstract
    • Richardson P, Schlossman R, Munshi N, et al. A phase 1 trial of lenalidomide (Revlimid®) with bortezomib (Velcade®) in relapsed and refractory multiple myeloma. Blood 2005; 106:110a (Abstract #365).
    • (2005) Blood , vol.106 , Issue.365
    • Richardson, P.1    Schlossman, R.2    Munshi, N.3
  • 24
    • 33644843725 scopus 로고    scopus 로고
    • Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: Randomized controlled trial
    • Palumbo A, Bringhen S, Caravita T, et al. Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomized controlled trial. Lancet 2006; 367:825-831.
    • (2006) Lancet , vol.367 , pp. 825-831
    • Palumbo, A.1    Bringhen, S.2    Caravita, T.3
  • 25
    • 33646901123 scopus 로고    scopus 로고
    • Major superiority of melphalan - prednisone (MP) + thalidomide (THAL) over MP and autologous stem cell transplantation in the treatment of newly diagnosed elderly patients with multiple myeloma
    • Abstract
    • Facon T, Mary JY, Hulin C, et al. Major superiority of melphalan - prednisone (MP) + thalidomide (THAL) over MP and autologous stem cell transplantation in the treatment of newly diagnosed elderly patients with multiple myeloma. Blood 2005; 106:230a (Abstract #780).
    • (2005) Blood , vol.106 , Issue.780
    • Facon, T.1    Mary, J.Y.2    Hulin, C.3
  • 26
    • 0043203040 scopus 로고    scopus 로고
    • Prospective randomized comparison of vincristine, doxorubicin and dexamethasone (VAD) administered as intravenous bolus injection and VAD with liposomal doxorubicin as first-line treatment in multiple myeloma
    • Dimopoulos MA, Pouli A, Zervas K. Prospective randomized comparison of vincristine, doxorubicin and dexamethasone (VAD) administered as intravenous bolus injection and VAD with liposomal doxorubicin as first-line treatment in multiple myeloma. Ann Oncol 2003; 14:1039-1044.
    • (2003) Ann Oncol , vol.14 , pp. 1039-1044
    • Dimopoulos, M.A.1    Pouli, A.2    Zervas, K.3
  • 27
    • 0032920397 scopus 로고    scopus 로고
    • Vincristine, doxorubicin and dexamethasone (VAD) administered as rapid intravenous infusion for first-line treatment in untreated multiple myeloma
    • Segeren CM, Sonneveld P, van der Holt B, et al. Vincristine, doxorubicin and dexamethasone (VAD) administered as rapid intravenous infusion for first-line treatment in untreated multiple myeloma. Br J Haematol 1999; 105:127-130.
    • (1999) Br J Haematol , vol.105 , pp. 127-130
    • Segeren, C.M.1    Sonneveld, P.2    van der Holt, B.3
  • 28
    • 32544446935 scopus 로고    scopus 로고
    • Pegylated liposomal doxorubicin, vincristine, and dexamethasone provide significant reduction in toxicity compared with doxorubicin, vincristine, and dexamethasone in patients with newly diagnosed multiple myeloma: A phase III multicenter randomized trial
    • Rifkin RM, Gregory SA, Mohrbacher A, et al. Pegylated liposomal doxorubicin, vincristine, and dexamethasone provide significant reduction in toxicity compared with doxorubicin, vincristine, and dexamethasone in patients with newly diagnosed multiple myeloma: a phase III multicenter randomized trial. Cancer 2006; 106:848-858.
    • (2006) Cancer , vol.106 , pp. 848-858
    • Rifkin, R.M.1    Gregory, S.A.2    Mohrbacher, A.3
  • 29
    • 22044452126 scopus 로고    scopus 로고
    • Superiority of thalidomide and dexamethasone over vincristine-doxorubicin dexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma
    • Cavo M, Zamagni E, Tosi P. Superiority of thalidomide and dexamethasone over vincristine-doxorubicin dexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma. Blood 2005; 106:35-39.
    • (2005) Blood , vol.106 , pp. 35-39
    • Cavo, M.1    Zamagni, E.2    Tosi, P.3
  • 30
    • 8944220233 scopus 로고    scopus 로고
    • A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma
    • Attal M, Harousseau JL, Stoppa AM, et al. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. N Engl J Med 1996; 335:91-97.
    • (1996) N Engl J Med , vol.335 , pp. 91-97
    • Attal, M.1    Harousseau, J.L.2    Stoppa, A.M.3
  • 31
    • 0037739753 scopus 로고    scopus 로고
    • High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma
    • Child JA, Morgan GJ, Davies FE, et al. High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N Engl J Med 2003; 348:1875-1883.
    • (2003) N Engl J Med , vol.348 , pp. 1875-1883
    • Child, J.A.1    Morgan, G.J.2    Davies, F.E.3
  • 32
    • 0034954989 scopus 로고    scopus 로고
    • Impact of complete remission with intensive therapy in patients with responsive multiple myeloma
    • Alexanian R, Weber D, Giralt S, et al. Impact of complete remission with intensive therapy in patients with responsive multiple myeloma. Bone Marrow Transplant 2001; 27:1037-1043.
    • (2001) Bone Marrow Transplant , vol.27 , pp. 1037-1043
    • Alexanian, R.1    Weber, D.2    Giralt, S.3
  • 33
    • 34249789423 scopus 로고    scopus 로고
    • Complete remission represents the major surrogate marker of long survival in multiple myeloma
    • Abstract
    • Wang M, Delasalle K, Thomas S, et al. Complete remission represents the major surrogate marker of long survival in multiple myeloma. Blood 2006; 108:123a (Abstract #403).
    • (2006) Blood , vol.108 , Issue.403
    • Wang, M.1    Delasalle, K.2    Thomas, S.3
  • 34
    • 0347815503 scopus 로고    scopus 로고
    • Single versus double autologous stem-cell transplantation for multiple myeloma
    • Attal M, Harousseau JL, Facon T, et al. Single versus double autologous stem-cell transplantation for multiple myeloma. N Engl J Med 2003; 349:2495-2502.
    • (2003) N Engl J Med , vol.349 , pp. 2495-2502
    • Attal, M.1    Harousseau, J.L.2    Facon, T.3
  • 35
    • 33746332717 scopus 로고    scopus 로고
    • Intensive versus double intensive therapy in untreated multiple myeloma: Final analysis of the HOVON 24 trial
    • Abstract
    • Sonneveld P, van der Holt B, Vellenga E, et al. Intensive versus double intensive therapy in untreated multiple myeloma: final analysis of the HOVON 24 trial. Blood 2005; 106:715a (Abstract #2545).
    • (2005) Blood , vol.106 , Issue.2545
    • Sonneveld, P.1    van der Holt, B.2    Vellenga, E.3
  • 36
    • 20044385393 scopus 로고    scopus 로고
    • Analysis of outcome following allogeneic haemopoietic stem cell transplantation for myeloma using myeloablative conditioning - evidence for a superior outcome using melphalan combined with total body irradiation
    • Hunter HM, Peggs K, Powles R, et al. Analysis of outcome following allogeneic haemopoietic stem cell transplantation for myeloma using myeloablative conditioning - evidence for a superior outcome using melphalan combined with total body irradiation. Br J Haematol 2005; 128:496-502.
    • (2005) Br J Haematol , vol.128 , pp. 496-502
    • Hunter, H.M.1    Peggs, K.2    Powles, R.3
  • 37
    • 0036750105 scopus 로고    scopus 로고
    • Fludatabine/melphalan conditioning for allogeneic transplantation in patients with multiple myeloma
    • Giralt S, Aleman A, Anagnostopoulos A, et al. Fludatabine/melphalan conditioning for allogeneic transplantation in patients with multiple myeloma. Bone Marrow Transplant 2002; 30:367-373.
    • (2002) Bone Marrow Transplant , vol.30 , pp. 367-373
    • Giralt, S.1    Aleman, A.2    Anagnostopoulos, A.3
  • 38
    • 0033783964 scopus 로고    scopus 로고
    • Randomized trial of alpha-interferon or dexamethasone as maintenance treatment for multiple myeloma
    • Alexanian R, Weber D, Dimopoulos M, et al. Randomized trial of alpha-interferon or dexamethasone as maintenance treatment for multiple myeloma. Am J Hematol 2000; 65:204-209.
    • (2000) Am J Hematol , vol.65 , pp. 204-209
    • Alexanian, R.1    Weber, D.2    Dimopoulos, M.3
  • 39
    • 0029005703 scopus 로고
    • Interferon-alpha for induction and maintenance in multiple myeloma: Results of two multicenter randomized trials and summary of other studies
    • Ludwig H, Cohen AM, Polliack A, et al. Interferon-alpha for induction and maintenance in multiple myeloma: results of two multicenter randomized trials and summary of other studies. Ann Oncol 1995; 6:467-476.
    • (1995) Ann Oncol , vol.6 , pp. 467-476
    • Ludwig, H.1    Cohen, A.M.2    Polliack, A.3
  • 40
    • 33751164196 scopus 로고    scopus 로고
    • Maintenance therapy with thalidomide improves survival in multiple myeloma patients
    • Attal M, Harousseau JL, Leyvraz S, et al. Maintenance therapy with thalidomide improves survival in multiple myeloma patients. Blood 2006; 108:3289-3294.
    • (2006) Blood , vol.108 , pp. 3289-3294
    • Attal, M.1    Harousseau, J.L.2    Leyvraz, S.3
  • 41
    • 19944426090 scopus 로고    scopus 로고
    • Results of a multicenter randomized phase II trial of thalidomide and prednisone maintenance therapy for multiple myeloma after autologous stem cell transplant
    • Stewart AK, Chen CI, Howson-Jan K. Results of a multicenter randomized phase II trial of thalidomide and prednisone maintenance therapy for multiple myeloma after autologous stem cell transplant. Clin Cancer Res 2004; 10:8170-8176.
    • (2004) Clin Cancer Res , vol.10 , pp. 8170-8176
    • Stewart, A.K.1    Chen, C.I.2    Howson-Jan, K.3
  • 42
    • 33644916110 scopus 로고    scopus 로고
    • Phase I/II trial assessing bortezomib and melphalan combination therapy for the treatment of patients with relapsed or refractory multiple myeloma
    • Berenson JR, Yang HH, Sadler K, et al. Phase I/II trial assessing bortezomib and melphalan combination therapy for the treatment of patients with relapsed or refractory multiple myeloma. J Clin Oncol 2006; 24:937-944.
    • (2006) J Clin Oncol , vol.24 , pp. 937-944
    • Berenson, J.R.1    Yang, H.H.2    Sadler, K.3
  • 43
    • 33744803947 scopus 로고    scopus 로고
    • A phase I trial of lenalidomide (Revlimid®) with bortezomib (Velcade®) in relapsed and refractory multiple myeloma
    • Abstract
    • Richardson P, Schlossman R, Munshi N, et al. A phase I trial of lenalidomide (Revlimid®) with bortezomib (Velcade®) in relapsed and refractory multiple myeloma. Blood 2005; 106:110a (Abstract #365).
    • (2005) Blood , vol.106 , Issue.365
    • Richardson, P.1    Schlossman, R.2    Munshi, N.3
  • 44
    • 33746340326 scopus 로고    scopus 로고
    • Velcade (V)-thalidomide (T)-dexamethasone (D) for advanced and refractory multiple myeloma (MM): Long-term follow-up of phase I-II UARK 2001-37 - superior outcome in patients with normal cytogenetics and no prior T
    • Abstract
    • Zangari M, Barlogie B, Burns MJ, et al. Velcade (V)-thalidomide (T)-dexamethasone (D) for advanced and refractory multiple myeloma (MM): long-term follow-up of phase I-II UARK 2001-37 - superior outcome in patients with normal cytogenetics and no prior T. Blood 2005; 106:717a (Abstract #2552).
    • (2005) Blood , vol.106 , Issue.2552
    • Zangari, M.1    Barlogie, B.2    Burns, M.J.3
  • 45
    • 34249804313 scopus 로고    scopus 로고
    • A multicenter, randomized, parallel-Group, double-blind, placebo-controlled study of lenalidomide plus dexamethasone versus dexamethasone alone in previously treated subjects with multiple myeloma
    • April 10-14, Sydney, Australia. Abstract
    • Weber D, Chen C, Niesvizky R, et al. A multicenter, randomized, parallel-Group, double-blind, placebo-controlled study of lenalidomide plus dexamethasone versus dexamethasone alone in previously treated subjects with multiple myeloma. The 10th International Myeloma Workshop; April 10-14, 2005; Sydney, Australia. Abstract #738.
    • (2005) The 10th International Myeloma Workshop , Issue.738
    • Weber, D.1    Chen, C.2    Niesvizky, R.3
  • 46
    • 34249795004 scopus 로고    scopus 로고
    • Wang M, Knight R, Dimopoulos M, et al. Comparison of lenalidomide in combination with dexamethasone to dexamethasone alone in patients who have received thalidomide in relapsed or refractory multiple myeloma (MM). J Clin Oncol 2006; 24(18 suppl):427s (Abstract #7522).
    • Wang M, Knight R, Dimopoulos M, et al. Comparison of lenalidomide in combination with dexamethasone to dexamethasone alone in patients who have received thalidomide in relapsed or refractory multiple myeloma (MM). J Clin Oncol 2006; 24(18 suppl):427s (Abstract #7522).
  • 47
    • 0035880256 scopus 로고    scopus 로고
    • Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration
    • Podar K, Tai YT, Davies FE, et al. Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration. Blood 2001; 98:428-435.
    • (2001) Blood , vol.98 , pp. 428-435
    • Podar, K.1    Tai, Y.T.2    Davies, F.E.3
  • 48
    • 0031225483 scopus 로고    scopus 로고
    • Interleukin-6 triggers cell growth via the ras-dependent mitogen-activated protein kinase cascade
    • Ogata A, Chauhan D, Teoh G, et al. Interleukin-6 triggers cell growth via the ras-dependent mitogen-activated protein kinase cascade. J Immunol 1997; 159:2212-2221.
    • (1997) J Immunol , vol.159 , pp. 2212-2221
    • Ogata, A.1    Chauhan, D.2    Teoh, G.3
  • 50
    • 13844309711 scopus 로고    scopus 로고
    • Clinical development of histone deacetylase inhibitors as anticancer agents
    • Drummond DC, Noble CO, Kirpotin DB, et al. Clinical development of histone deacetylase inhibitors as anticancer agents. Annu Rev Pharmacol Toxicol 2005; 45:495-528.
    • (2005) Annu Rev Pharmacol Toxicol , vol.45 , pp. 495-528
    • Drummond, D.C.1    Noble, C.O.2    Kirpotin, D.B.3
  • 51
    • 16244366803 scopus 로고    scopus 로고
    • Class II histone deacetylases: From sequence to function, regulation, and clinical implication
    • Yang XJ, Gregoire S. Class II histone deacetylases: from sequence to function, regulation, and clinical implication. Mol Cell Biol 2005; 25:2873-2884.
    • (2005) Mol Cell Biol , vol.25 , pp. 2873-2884
    • Yang, X.J.1    Gregoire, S.2
  • 52
    • 0042090495 scopus 로고    scopus 로고
    • Novel mechanisms of apoptosis induced by histone deacetylase inhibitors
    • Peart MJ, Tainton KM, Ruefli AA, et al. Novel mechanisms of apoptosis induced by histone deacetylase inhibitors. Cancer Res 2003; 63:4460-4471.
    • (2003) Cancer Res , vol.63 , pp. 4460-4471
    • Peart, M.J.1    Tainton, K.M.2    Ruefli, A.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.