Perfusion culture process plus H2O2 stimulation for efficient astaxanthin production by Xanthophyllomyces dendrorhous

Biotechnology and Bioengineering

Volumn 97, Issue 3, 2007, Pages 568-573

  Yuan, Shuai Liu ^a   Wu, Jian Yong ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

Astaxanthin; H2O2 stimulation; Perfusion process; Repeated fed batch; Xanthophyllomyces dendrorhous

Indexed keywords

BIOMASS; METABOLITES;

ASTAXANTHIN; H2O2 SIMULATION; PERFUSION PROCESS; REPEATED FED-BATCH; XANTHOPHYLLOMYCES DENDRORHOUS;

CELL CULTURE;

ACETIC ACID; ALCOHOL; ASTAXANTHIN; GLUCOSE; HYDROGEN PEROXIDE;

ARTICLE; FUNGAL BIOMASS; FUNGUS CULTURE; PHAFFIA RHODOZYMA;

BASIDIOMYCOTA; CULTURE MEDIA; FERMENTATION; HYDROGEN PEROXIDE; INDUSTRIAL MICROBIOLOGY; MICROBIOLOGICAL TECHNIQUES; PERFUSION; XANTHOPHYLLS;

XANTHOPHYLLOMYCES DENDRORHOUS; ZEA MAYS;

EID: 34249781107     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21256     Document Type: Article

References (20)

1. An GH, Kim CH, Choi ES, Rhee SK. 1996. Medium optimization for cultivation of carotenoid hyperproducing Phaffia rhodozyma mutant HT-5FO1C. J Ferment Bioeng 82:515-518.
2. Andrewes AG, Phaff HJ, Starr MP. 1976. Carotenoids of Phaffia rhodozyma, a red-pigmented fermenting yeast. Phytochemistry 15:1003-1007.
3. Ducrey Santopietro LM, Spencer JFT, Spencer DM, Sińeriz F. 1998. Fed-batch and continuous culture of Phaffia rhodozyma (Xanthophyllomyces dendrorhous). Folia Microbiol 43:169-172.
4. Fiechter A, Seghezzi W. 1992. Regulation of glucose metabolism in growing yeast cells. J Biotechnol 27:27-45.
5. Guerin M, Huntley MF, Olaizola M. 2003. Haematococcus astaxanthin: Applications for human health and nutrition. Trends Biotechnol 21: 210-216.
6. Hoek PV, Dijken JPV, Pronk JT. 1998. Effect of specific growth rate on fermentative capacity of baker's yeast. Appl Environ Microbiol 64: 4226-4233.
7. Johnson EA. 2003. Phaffia rhodozyma: Colorful Odyssey. Int Microbiol 6: 169-174.
8. Johnson EA, Schroeder WA. 1995. Microbial carotenoids production. Adv Biochem Eng 53:119-178.
9. Jones JB. 1991. Kjeldahl method for nitrogen determination. Athens, GA: Micro-macro Publishing.
10. Kretzmer G. 2002. Industrial processes with animal cells. Appl Microbiol Biotechnol 59:135-142.
11. Lababpour A, Shimahara K, Hada K, Kyoui Y, Katsuda T, Katoh S. 2005. Fed-batch culture under illumination with blue light emitting diodes (LEDs) for astaxanthin production by Haematococcus pluvialis. J Biosci Bioneng 100:339-342.
12. Liu YS, Wu JY. 2006. Hydrogen peroxide-induced astaxanthin biosynthesis and catalase activity in Xanthophyllomyces dendrorhous. Appl Microbiol Biotechnol 73:663-668.
13. Liu YS, Wu JY, Ho KP. 2006. Characterization of oxygen transfer conditions and their effects on Phaffia rhodozyma growth and carotenoid production in shake-flask cultures. Biochem Eng J 27:331-335.
14. Meyer PS, Du Preez JC. 1994. Effect of culture conditions on astaxanthin production by a mutant of Phaffia rhodozyma in batch and chemostat culture. Appl Microbiol Biotechnol 40:780-785.
15. Postma E, Verduyn C, Scheffers WA, Dijken JPV. 1989. Enzymic analysis of the Crabtree effect in glucose-limited chemostat cultures of Saccharomyces cereviciae. Appl Environ Microbiol 55:468-477.
16. Reynders MB, Rawlings DE, Harrison STL. 1997. Demonstration of the Crabtree effect in Phaffia rhodozyma during continuous and fed-batch cultivation. Biotechnol Lett 19:549-552.
17. Schroeder WA, Johnson EA. 1995. Carotenoids protect Phaffia rhodozyma against singlet oxygen damage. J Ind Microbiol 270:502-507.
18. Todd Lorenz R, Cysewski GR. 2000. Commercial potential for Haematococcus microalgae as a natural source of astaxanthin. Trends Biotechnol 18:160-167.
19. Yamane Y, Higashida K, Nakashimada Y, Kakizono T, Nishio N. 1997. Influence of oxygen and glucose on primary metabolism and astaxanthin production by Phaffia rhodozyma in batch and fed-batch cultures: Kinetic and stoichiometric analysis. Appl Environ Microbiol 63:4471-4478.
20. Zhang XW, Gong XD, Chen F. 1999. Kinetic models for astaxanthin production by high cell density mixotrophic culture of the microalga Haematococcus pluvialis. J Ind Microbiol Biotechnol 23:691-696.