-
1
-
-
13444293396
-
Anti-amnestic and anti-aging effects of ginsenoside Rg1 and Rb1 and its mechanism of action
-
Cheng Y., Shen L.H., and Zhang J.T. Anti-amnestic and anti-aging effects of ginsenoside Rg1 and Rb1 and its mechanism of action. Acta Pharmacol. Sin. 26 (2005) 143-149
-
(2005)
Acta Pharmacol. Sin.
, vol.26
, pp. 143-149
-
-
Cheng, Y.1
Shen, L.H.2
Zhang, J.T.3
-
2
-
-
24044443225
-
Radioprotective potential of ginseng
-
Lee T.K., Johnke R.M., Allison R.R., O'Brien K.F., and Dobbs Jr. L.J. Radioprotective potential of ginseng. Mutagenesis 20 (2005) 237-243
-
(2005)
Mutagenesis
, vol.20
, pp. 237-243
-
-
Lee, T.K.1
Johnke, R.M.2
Allison, R.R.3
O'Brien, K.F.4
Dobbs Jr., L.J.5
-
3
-
-
33644634193
-
Ginsenoside Rd from Panax notoginseng is cytotoxic towards HeLa cancer cells and induces apoptosis
-
Yang Z.G., Sun H.X., and Ye Y.P. Ginsenoside Rd from Panax notoginseng is cytotoxic towards HeLa cancer cells and induces apoptosis. Chem. Biodivers. 3 (2006) 187-197
-
(2006)
Chem. Biodivers.
, vol.3
, pp. 187-197
-
-
Yang, Z.G.1
Sun, H.X.2
Ye, Y.P.3
-
4
-
-
33845230376
-
Ginsenoside Rd elicits Th1 and Th2 immune responses to ovalbumin in mice
-
Yang Z., Chen A., Sun H.X., Ye Y.P., and Fang W.H. Ginsenoside Rd elicits Th1 and Th2 immune responses to ovalbumin in mice. Vaccine 25 (2007) 161-169
-
(2007)
Vaccine
, vol.25
, pp. 161-169
-
-
Yang, Z.1
Chen, A.2
Sun, H.X.3
Ye, Y.P.4
Fang, W.H.5
-
5
-
-
33748690115
-
2+ channels in vascular smooth muscle cells
-
2+ channels in vascular smooth muscle cells. Eur. J. Pharmacol. 548 (2006) 129-136
-
(2006)
Eur. J. Pharmacol.
, vol.548
, pp. 129-136
-
-
Guan, Y.Y.1
Zhou, J.G.2
Zhang, Z.3
Wang, G.L.4
Cai, B.X.5
Hong, L.6
Qiu, Q.Y.7
He, H.8
-
6
-
-
0029086681
-
Specificity of expression and effects of eicosanoid mediators in normal physiology and human diseases
-
Goetzl E.J., An S., and Smith W.L. Specificity of expression and effects of eicosanoid mediators in normal physiology and human diseases. FASEB J. 9 (1995) 1051-1058
-
(1995)
FASEB J.
, vol.9
, pp. 1051-1058
-
-
Goetzl, E.J.1
An, S.2
Smith, W.L.3
-
8
-
-
0028899434
-
Proinflammatory cytokines regulate cyclooxygenase-2 mRNA expression in human macrophages
-
Arias-Negrete S., Keller K., and Chadee K. Proinflammatory cytokines regulate cyclooxygenase-2 mRNA expression in human macrophages. Biochem. Biophys. Res. Commun. 208 (1995) 582-589
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.208
, pp. 582-589
-
-
Arias-Negrete, S.1
Keller, K.2
Chadee, K.3
-
9
-
-
0035013596
-
Cyclooxygenase-2 upregulation as a perigenetic change in carcinogenesis
-
Tsuji S., Tsujii M., Kawano S., and Hori M. Cyclooxygenase-2 upregulation as a perigenetic change in carcinogenesis. J. Exp. Clin. Cancer Res. 20 (2001) 117-129
-
(2001)
J. Exp. Clin. Cancer Res.
, vol.20
, pp. 117-129
-
-
Tsuji, S.1
Tsujii, M.2
Kawano, S.3
Hori, M.4
-
10
-
-
0028226265
-
Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2
-
Kosaka T., Miyata A., Ihara H., Hara S., Sugimoto T., Takeda O., Takahashi E., and Tanabe T. Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2. Eur. J. Biochem. 221 (1994) 889-897
-
(1994)
Eur. J. Biochem.
, vol.221
, pp. 889-897
-
-
Kosaka, T.1
Miyata, A.2
Ihara, H.3
Hara, S.4
Sugimoto, T.5
Takeda, O.6
Takahashi, E.7
Tanabe, T.8
-
11
-
-
0032538428
-
Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells. Regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues
-
Kim Y., and Fischer S.M. Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells. Regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues. J. Biol. Chem. 273 (1998) 27686-27694
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 27686-27694
-
-
Kim, Y.1
Fischer, S.M.2
-
12
-
-
0035939790
-
Role of cyclic AMP responsive element in the UVB induction of cyclooxygenase-2 transcription in human keratinocytes
-
Tang Q., Chen W., Gonzales M.S., Finch J., Inoue H., and Bowden G.T. Role of cyclic AMP responsive element in the UVB induction of cyclooxygenase-2 transcription in human keratinocytes. Oncogene 20 (2001) 5164-5172
-
(2001)
Oncogene
, vol.20
, pp. 5164-5172
-
-
Tang, Q.1
Chen, W.2
Gonzales, M.S.3
Finch, J.4
Inoue, H.5
Bowden, G.T.6
-
13
-
-
0037838859
-
Ceramide-induced and age-associated increase in macrophage COX-2 expression is mediated through up-regulation of NF-kappa B activity
-
Wu D., Marko M., Claycombe K., Paulson K.E., and Meydani S.N. Ceramide-induced and age-associated increase in macrophage COX-2 expression is mediated through up-regulation of NF-kappa B activity. J. Biol. Chem. 278 (2003) 10983-10992
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10983-10992
-
-
Wu, D.1
Marko, M.2
Claycombe, K.3
Paulson, K.E.4
Meydani, S.N.5
-
14
-
-
33745006365
-
Bifunctional effects of fucoidan on the expression of inducible nitric oxide synthase
-
Yang J.W., Yoon S.Y., Oh S.J., Kim S.K., and Kang K.W. Bifunctional effects of fucoidan on the expression of inducible nitric oxide synthase. Biochem. Biophys. Res. Commun. 346 (2006) 345-350
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.346
, pp. 345-350
-
-
Yang, J.W.1
Yoon, S.Y.2
Oh, S.J.3
Kim, S.K.4
Kang, K.W.5
-
15
-
-
0031559584
-
Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta
-
Newton R., Kuitert L.M., Bergmann M., Adcock I.M., and Barnes P.J. Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta. Biochem. Biophys. Res. Commun. 237 (1997) 28-32
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.237
, pp. 28-32
-
-
Newton, R.1
Kuitert, L.M.2
Bergmann, M.3
Adcock, I.M.4
Barnes, P.J.5
-
16
-
-
0029860947
-
Evidence for common mechanisms in the transcriptional control of type II nitric oxide synthase in isolated hepatocytes. Requirement of NF-kappaB activation after stimulation with bacterial cell wall products and phorbol esters
-
Diaz-Guerra M.J., Velasco M., Martin-Sanz P., and Bosca L. Evidence for common mechanisms in the transcriptional control of type II nitric oxide synthase in isolated hepatocytes. Requirement of NF-kappaB activation after stimulation with bacterial cell wall products and phorbol esters. J. Biol. Chem. 271 (1996) 30114-30120
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30114-30120
-
-
Diaz-Guerra, M.J.1
Velasco, M.2
Martin-Sanz, P.3
Bosca, L.4
-
17
-
-
0033709813
-
Critical role of C/EBP-beta and C/EBP-delta factors in the stimulation of the cyclooxygenase-2 gene transcription by interleukin-1 in articular chondrocytes
-
Thomas B., Berenbaum F., Humbert L., Bian H., Bereziat G., Crofford L., and Olivier J.L. Critical role of C/EBP-beta and C/EBP-delta factors in the stimulation of the cyclooxygenase-2 gene transcription by interleukin-1 in articular chondrocytes. Eur. J. Biochem. 267 (2000) 6798-6809
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 6798-6809
-
-
Thomas, B.1
Berenbaum, F.2
Humbert, L.3
Bian, H.4
Bereziat, G.5
Crofford, L.6
Olivier, J.L.7
-
18
-
-
0041852764
-
Induction of cyclooxygenase-2 in human endometrial stromal cells by malignant endometrial epithelial cells: evidence for the involvement of extracellularly regulated kinases and CCAAT/enhancer binding proteins
-
Tamura M., Sebastian S., Yang S., Gurates B., Fang Z., Okamura K., and Bulun S.E. Induction of cyclooxygenase-2 in human endometrial stromal cells by malignant endometrial epithelial cells: evidence for the involvement of extracellularly regulated kinases and CCAAT/enhancer binding proteins. J. Mol. Endocrinol. 31 (2003) 95-104
-
(2003)
J. Mol. Endocrinol.
, vol.31
, pp. 95-104
-
-
Tamura, M.1
Sebastian, S.2
Yang, S.3
Gurates, B.4
Fang, Z.5
Okamura, K.6
Bulun, S.E.7
-
19
-
-
33845996148
-
Inflammation, cancer, and targets of ginseng
-
Hofseth L.J., and Wargovich M.J. Inflammation, cancer, and targets of ginseng. J. Nutr. 137 (2007) 183S-185S
-
(2007)
J. Nutr.
, vol.137
-
-
Hofseth, L.J.1
Wargovich, M.J.2
-
20
-
-
0032959141
-
Up-regulation of interleukin-1beta-stimulated interleukin-8 in human keratinocytes by nitric oxide
-
Andrew P.J., Harant H., and Lindley I.J. Up-regulation of interleukin-1beta-stimulated interleukin-8 in human keratinocytes by nitric oxide. Biochem. Pharmacol. 57 (1999) 1423-1429
-
(1999)
Biochem. Pharmacol.
, vol.57
, pp. 1423-1429
-
-
Andrew, P.J.1
Harant, H.2
Lindley, I.J.3
-
21
-
-
0035678118
-
Stimulation of nitric oxide synthesis by the aqueous extract of Panax ginseng root in RAW 264.7 cells
-
Friedl R., Moeslinger T., Kopp B., and Spieckermann P.G. Stimulation of nitric oxide synthesis by the aqueous extract of Panax ginseng root in RAW 264.7 cells. Br. J. Pharmacol. 134 (2001) 1663-1670
-
(2001)
Br. J. Pharmacol.
, vol.134
, pp. 1663-1670
-
-
Friedl, R.1
Moeslinger, T.2
Kopp, B.3
Spieckermann, P.G.4
-
22
-
-
0242492625
-
Ginsenoside Rg3 inhibits phenylephrine- induced vascular contraction through induction of nitric oxide synthase
-
Kim N.D., Kim E.M., Kang K.W., Cho M.K., Choi S.Y., and Kim S.G. Ginsenoside Rg3 inhibits phenylephrine- induced vascular contraction through induction of nitric oxide synthase. Br. J. Pharmacol. 140 (2003) 661-670
-
(2003)
Br. J. Pharmacol.
, vol.140
, pp. 661-670
-
-
Kim, N.D.1
Kim, E.M.2
Kang, K.W.3
Cho, M.K.4
Choi, S.Y.5
Kim, S.G.6
-
23
-
-
33846618796
-
Differential effects of ginsenosides on NO and TNF-alpha production by LPS-activated N9 microglia
-
Wu C.F., Bi X.L., Yang J.Y., Zhan J.Y., Dong Y.X., Wang J.H., Wang J.M., Zhang R., and Li X. Differential effects of ginsenosides on NO and TNF-alpha production by LPS-activated N9 microglia. Int. Immunopharmacol. 7 (2007) 313-320
-
(2007)
Int. Immunopharmacol.
, vol.7
, pp. 313-320
-
-
Wu, C.F.1
Bi, X.L.2
Yang, J.Y.3
Zhan, J.Y.4
Dong, Y.X.5
Wang, J.H.6
Wang, J.M.7
Zhang, R.8
Li, X.9
-
24
-
-
21144444049
-
Inhibitory effect of ginsenoside Rb1 and compound K on NO and prostaglandin E2 biosyntheses of RAW264.7 cells induced by lipopolysaccharide
-
Park E.K., Shin Y.W., Lee H.U., Kim S.S., Lee Y.C., Lee B.Y., and Kim D.H. Inhibitory effect of ginsenoside Rb1 and compound K on NO and prostaglandin E2 biosyntheses of RAW264.7 cells induced by lipopolysaccharide. Biol. Pharm. Bull. 28 (2005) 652-656
-
(2005)
Biol. Pharm. Bull.
, vol.28
, pp. 652-656
-
-
Park, E.K.1
Shin, Y.W.2
Lee, H.U.3
Kim, S.S.4
Lee, Y.C.5
Lee, B.Y.6
Kim, D.H.7
-
25
-
-
33745683962
-
Ginsenosides Rg3 and Rh2 inhibit the activation of AP-1 and protein kinase A pathway in lipopolysaccharide/interferon-gamma-stimulated BV-2 microglial cells
-
Bae E.A., Kim E.J., Park J.S., Kim H.S., Ryu J.H., and Kim D.H. Ginsenosides Rg3 and Rh2 inhibit the activation of AP-1 and protein kinase A pathway in lipopolysaccharide/interferon-gamma-stimulated BV-2 microglial cells. Planta Med. 72 (2006) 627-633
-
(2006)
Planta Med.
, vol.72
, pp. 627-633
-
-
Bae, E.A.1
Kim, E.J.2
Park, J.S.3
Kim, H.S.4
Ryu, J.H.5
Kim, D.H.6
-
26
-
-
33645004900
-
Inhibitory effects of ginsenoside-Rb1 on activation of the 12-O-tetradecanoylphorbol 13-acetate-induced cyclooxygenase-2 promoter
-
Park W., Lim W., Cho J., Inoue H., Rhyu M.R., and Lee Y. Inhibitory effects of ginsenoside-Rb1 on activation of the 12-O-tetradecanoylphorbol 13-acetate-induced cyclooxygenase-2 promoter. Planta Med. 72 (2006) 272-275
-
(2006)
Planta Med.
, vol.72
, pp. 272-275
-
-
Park, W.1
Lim, W.2
Cho, J.3
Inoue, H.4
Rhyu, M.R.5
Lee, Y.6
-
27
-
-
0036070816
-
Transcriptional regulation of basal cyclooxygenase-2 expression in murine lung tumor-derived cell lines by CCAAT/enhancer-binding protein and activating transcription factor/cAMP response element-binding protein
-
Wardlaw S.A., Zhang N., and Belinsky S.A. Transcriptional regulation of basal cyclooxygenase-2 expression in murine lung tumor-derived cell lines by CCAAT/enhancer-binding protein and activating transcription factor/cAMP response element-binding protein. Mol. Pharmacol. 62 (2002) 326-333
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 326-333
-
-
Wardlaw, S.A.1
Zhang, N.2
Belinsky, S.A.3
-
29
-
-
0036093865
-
Inflammation and the development of pancreatic cancer
-
Farrow B., and Evers B.M. Inflammation and the development of pancreatic cancer. Surg. Oncol. 10 (2002) 153-169
-
(2002)
Surg. Oncol.
, vol.10
, pp. 153-169
-
-
Farrow, B.1
Evers, B.M.2
-
30
-
-
0035296203
-
Role of nitric oxide in carcinogenesis and tumour progression
-
Lala P.K., and Chakraborty C. Role of nitric oxide in carcinogenesis and tumour progression. Lancet Oncol. 2 (2001) 149-156
-
(2001)
Lancet Oncol.
, vol.2
, pp. 149-156
-
-
Lala, P.K.1
Chakraborty, C.2
-
31
-
-
4544327894
-
Cyclooxygenases in cancer: progress and perspective
-
Zha S., Yegnasubramanian V., Nelson W.G., Isaacs W.B., and De Marzo A.M. Cyclooxygenases in cancer: progress and perspective. Cancer Lett. 215 (2004) 1-20
-
(2004)
Cancer Lett.
, vol.215
, pp. 1-20
-
-
Zha, S.1
Yegnasubramanian, V.2
Nelson, W.G.3
Isaacs, W.B.4
De Marzo, A.M.5
-
32
-
-
0036156229
-
Cyclooxygenase-2 expression during carcinogenesis in the human stomach
-
van Rees B.P., Saukkonen K., Ristimaki A., Polkowski W., Tytgat G.N., Drillenburg P., and Offerhaus G.J. Cyclooxygenase-2 expression during carcinogenesis in the human stomach. J. Pathol. 196 (2002) 171-179
-
(2002)
J. Pathol.
, vol.196
, pp. 171-179
-
-
van Rees, B.P.1
Saukkonen, K.2
Ristimaki, A.3
Polkowski, W.4
Tytgat, G.N.5
Drillenburg, P.6
Offerhaus, G.J.7
-
33
-
-
0034685876
-
Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 and p38-mitogen-activated protein kinase pathways
-
Subbaramaiah K., Hart J.C., Norton L., and Dannenberg A.J. Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 and p38-mitogen-activated protein kinase pathways. J. Biol. Chem. 275 (2000) 14838-14845
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 14838-14845
-
-
Subbaramaiah, K.1
Hart, J.C.2
Norton, L.3
Dannenberg, A.J.4
-
35
-
-
20144388887
-
Cyclooxygenase-2 inhibits novel ginseng metabolite-mediated apoptosis
-
Yim H.W., Jong H.S., Kim T.Y., Choi H.H., Kim S.G., Song S.H., Kim J., Ko S.G., Lee J.W., Kim T.Y., and Bang Y.J. Cyclooxygenase-2 inhibits novel ginseng metabolite-mediated apoptosis. Cancer Res. 65 (2005) 1952-1960
-
(2005)
Cancer Res.
, vol.65
, pp. 1952-1960
-
-
Yim, H.W.1
Jong, H.S.2
Kim, T.Y.3
Choi, H.H.4
Kim, S.G.5
Song, S.H.6
Kim, J.7
Ko, S.G.8
Lee, J.W.9
Kim, T.Y.10
Bang, Y.J.11
-
36
-
-
25144439383
-
Experimental and epidemiological evidence on non-organ specific cancer preventive effect of Korean ginseng and identification of active compounds
-
Yun T.K. Experimental and epidemiological evidence on non-organ specific cancer preventive effect of Korean ginseng and identification of active compounds. Mutat. Res. 63-74 (2003) 523-524
-
(2003)
Mutat. Res.
, vol.63-74
, pp. 523-524
-
-
Yun, T.K.1
-
37
-
-
0033093123
-
Ginsenoside-Rs4, a new type of ginseng saponin concurrently induces apoptosis and selectively elevates protein levels of p53 and p21WAF1 in human hepatoma SK-HEP-1 cells
-
Kim S.E., Lee Y.H., Park J.H., and Lee S.K. Ginsenoside-Rs4, a new type of ginseng saponin concurrently induces apoptosis and selectively elevates protein levels of p53 and p21WAF1 in human hepatoma SK-HEP-1 cells. Eur. J. Cancer. 35 (1999) 507-511
-
(1999)
Eur. J. Cancer.
, vol.35
, pp. 507-511
-
-
Kim, S.E.1
Lee, Y.H.2
Park, J.H.3
Lee, S.K.4
-
38
-
-
0036207452
-
Apoptotic effects of ginsenoside Rh2 on human malignant melanoma A375-S2 cells
-
Fei X.F., Wang B.X., Tashiro S., Li T.J., Ma J.S., and Ikejima T. Apoptotic effects of ginsenoside Rh2 on human malignant melanoma A375-S2 cells. Acta Pharmacol. Sin. 23 (2002) 315-322
-
(2002)
Acta Pharmacol. Sin.
, vol.23
, pp. 315-322
-
-
Fei, X.F.1
Wang, B.X.2
Tashiro, S.3
Li, T.J.4
Ma, J.S.5
Ikejima, T.6
|