Enantioselective determination of azelnidipine in human plasma using liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 852, Issue 1-2, 2007, Pages 389-397

  Kawabata, Kiyoshi ^a   Samata, Naozumi ^a   Urasaki, Yoko ^a   Fukazawa, Ichiro ^b   Uchida, Naoki ^b   Uchida, Eiji ^b   Yasuhara, Hajime ^b  

^a DAIICHI SANKYO CO   (Japan)

^b SHOWA UNIVERSITY   (Japan)

Author keywords

Azelnidipine; Enantiomer separation; LC APCI MS MS; Quantitative analysis

Indexed keywords

COMPUTATION THEORY; IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PLASMA (HUMAN); REGRESSION ANALYSIS;

AZELNIDIPINE; ENANTIOMER SEPARATION; SOLUTION STABILITY;

ENANTIOMERS;

AZELNIDIPINE;

AREA UNDER THE CURVE; ARTICLE; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG ISOLATION; ENANTIOSELECTIVITY; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; MALE; NORMAL HUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SINGLE DRUG DOSE; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

AZETIDINECARBOXYLIC ACID; CALCIUM CHANNEL BLOCKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIHYDROPYRIDINES; HUMANS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM; TANDEM MASS SPECTROMETRY;

EID: 34249724508     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.01.050     Document Type: Article

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