Diversity of Ca2+-induced morphology revealed by morphological phenotyping of Ca2+-sensitive mutants of Saccharomyces cerevisiae

Eukaryotic Cell

Volumn 6, Issue 5, 2007, Pages 817-830

  Ohnuki, Shinsuke ^a   Nogami, Satoru ^a,b   Kanai, Hanako ^a   Hirata, Dai ^c   Nakatani, Yoichiro ^a,b   Morishita, Shinichi ^a,b   Ohya, Yoshikazu ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

SACCHAROMYCES CEREVISIAE;

CALCIUM; MUTANT PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; BIOLOGICAL MODEL; CLUSTER ANALYSIS; CYTOLOGY; DRUG EFFECT; GENETICS; ISOLATION AND PURIFICATION; MUTATION; PHENOTYPE; SACCHAROMYCES CEREVISIAE;

CALCIUM; CLUSTER ANALYSIS; MODELS, BIOLOGICAL; MUTANT PROTEINS; MUTATION; PHENOTYPE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 34249721467     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00012-07     Document Type: Article

References (34)

1. Allison, D. B., X. Cui, G. P. Page, and M. Sabripour. 2006. Microarray data analysis: from disarray to consolidation and consensus. Nat. Rev. Genet. 7:55-65.
2. Bi, E., and J. R. Pringle. 1996. ZDS1 and ZDS2, genes whose products may regulate Cdc42p in Saccharomyces cerevisiae. Mol. Cell. Biol. 16: 5264-5275.
3. Brown, J. A., G. Sherlock, C. L. Myers, N. M. Burrows, C. Deng, H. I. Wu, K. E. McCann, O. G. Troyanskaya, and J. M. Brown. 2006. Global analysis of gene function in yeast by quantitative phenotypic profiling. Mol. Syst. Biol 2:2006.0001.
4. Churchill, G. A., and R. W. Doerge. 1994. Empirical threshold values for quantitative trait mapping. Genetics 138:963-971.
5. Coleman, K. G., H. Y. Steensma, D. B. Kaback, and J. R. Pringle. 1986. Molecular cloning of chromosome 1 DNA from Saccharomyces cerevisiae: isolation and characterization of the CDC24 gene and adjacent regions of the chromosome. Mol. Cell. Biol. 6:4516-4525.
6. 2+ ATPases. J. Cell Biol. 124:351-363.
7. Eisen, M. B., P. T. Spellman, P. O. Brown, and D. Botstein. 1998. Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. USA 95:14863-14868.
8. Garge, N. R., G. P. Page, A. P. Sprague, B. S. Gorman, and D. B. Allison. 2005. Reproducible clusters from microarray research: whither? BMC Bioinformatics 6(Suppl. 2):S10.
9. Hartwell, L. H. 1991. Twenty-five years of cell cycle genetics. Genetics 129:975-980.
10. +-ATPase subunits onto the vacuolar membrane in Saccharomyces cerevisiae. J. Biol. Chem. 268:961-967.
11. Kohane, I. S., A. T. Kho, and A. J. Butte. 2003. Microarrays for an integrative genomics. MIT Press, Cambridge, MA.
12. Kucharczyk, R., A. M. Kierzek, P. P. Slonimski, and J. Rytka. 2001. The Ccz1 protein interacts with Ypt7 GTPase during fusion of multiple transport intermediates with the vacuole in S. cerevisiae. J. Cell Sci. 114:3137-3145.
13. Kwok, E. Y., S. Severance, and D. J. Kosman. 2006. Evidence for iron channeling in the Fct3p-Ftr1p high-affinity iron uptake complex in the yeast plasma membrane. Biochemistry 45:6317-6327.
14. Lord, P. G., and A. E. Wheals. 1983. Rate of cell cycle initiation of yeast cells when cell size is not a rate-determining factor. J. Cell Sci. 59:183-201.
15. Lynn, R. R., and P. T. Magee. 1970. Development of the spore wall during ascospore formation in Saccharomyces cerevisiae. J. Cell Biol. 44:688-692.
16. Mann, H. B., and D. R. Whitney. 1947. On a test of whether of two random variables is stochastically larger than the other. Ann. Math. Stat. 18:50-60.
17. Mizunuma, M., D. Hirata, K. Miyahara, E. Tsuchiya, and T. Miyakawa. 1998. Role of calcineurin and Mpk1 in regulating the onset of mitosis in budding yeast. Nature 392:303-306.
18. 1 cell-cycle regulation in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 101:6086-6091.
19. Mosch, H. U., and G. R. Fink. 1997. Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145:671-684.
20. Ohya, Y., S. Miyamoto, Y. Ohsumi, and Y. Anraku. 1986. Calcium-sensitive cls4 mutant of Saccharomyces cerevisiae with a defect in bud formation. J. Bacteriol. 165:28-33.
21. 2+-sensitive mutants of Saccharomyces cerevisiae. J. Gen. Microbiol. 132: 979-988.
22. Ohya, Y., J. Sese, M. Yukawa, F. Sano, Y. Nakatani, T. L. Saito, A. Saka, T. Fukuda, S. Ishihara, S. Oka, G. Suzuki, M. Watanabe, A. Hirata, M. Ohtani, H. Sawai, N. Fraysse, J. P. Latge, J. M. Francois, M. Aebi, S. Tanaka, S. Muramatsu, H. Araki, K. Sonoike, S. Nogami, and S. Morishita. 2005. High-dimensional and large-scale phenotyping of yeast mutants. Proc. Natl. Acad. Sci. USA 102:19015-19020.
23. +-ATPase activity. J. Biol. Chem. 266:13971-13977.
24. Pruyne, D., and A. Bretscher. 2000. Polarization of cell growth in yeast. I. Establishment and maintenance of polarity states. J. Cell Sci. 113:365-375.
25. Rieder, S. E., and S. D. Emr. 1997. A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole. Mol. Biol Cell 8:2307-2327.
26. Sambade, M., M. Alba, A. M. Smardon, R. W. West, and P. M. Kane. 2005. A genomic screen for yeast vacuolar membrane ATPase mutants. Genetics 170:1539-1551.
27. Suzuki, R., and H. Shimodaira. 2006. Pvclust: an R package for assessing the uncertainty in hierarchical clustering. Bioinformatics 22:1540-1542.
28. 2+ tolerance in yeast. Mol. Gen. Genet. 246:269-281.
29. Trueheart, J., J. D. Boeke, and G. R. Fink. 1987. Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein. Mol. Cell. Biol. 7:2316-2328.
30. Wada, Y., Y. Ohsumi, and Y. Anraku. 1992. Genes for directing vacuolar morphogenesis in Saccharomyces cerevisiae. I. Isolation and characterization of two classes of vam mutants. J. Biol. Chem. 267:18665-18670.
31. 2 cell-cycle regulation in Saccharomyces cerevisiae. EMBO Rep. 7:519-524.
32. Yoshimoto, H., K. Saltsman, A. P. Gasch, H. X. Li, N. Ogawa, D. Botstein, P. O. Brown, and M. S. Cyert. 2002. Genome-wide analysis of gene expression regulated by the calcineurin/Crz1p signaling pathway in Saccharomyces cerevisiae. J. Biol. Chem. 277:31079-31088.
33. Yu, Y., Y. W. Jiang, R. J. Wellinger, K. Carlson, J. M. Roberts, and D. J. Stillman. 1996. Mutations in the homologous ZDS1 and ZDS2 genes affect cell cycle progression. Mol. Cell. Biol. 16:5254-5263.
34. Zhang, J. W., K. J. Parra, J. Liu, and P. M. Kane. 1998. Characterization of a temperature-sensitive yeast vacuolar ATPase mutant with defects in actin distribution and bud morphology. J. Biol. Chem. 273:18470-18480.