In silico identification and characterization of a putative phosphatidylinositol 4-phosphate 5-kinase (PIP5K) gene in Eimeria tenella

In Silico Biology

Volumn 7, Issue 1, 2007, Pages 115-121

  Ling, King Hwa ^a,b   Loo, Shu San ^a   Rosli, Rozita ^a,b   Shamsudin, Mariana Nor ^a,b   Mohamed, Rahmah ^a   Wan, Kiew Lian ^a  

^a UNIVERSITI KEBANGSAAN MALAYSIA   (Malaysia)

^b UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Eimeria tenella; Homology based approach; Intron exon splicing; Phosphatidylinositol 4 phosphate 5 kinase; Protein fold recognition; Threading

Indexed keywords

COMPLEMENTARY DNA; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE;

ARTICLE; BIOINFORMATICS; COMPUTER MODEL; COMPUTER PREDICTION; CONSENSUS SEQUENCE; CONTROLLED STUDY; EIMERIA TENELLA; EXON; GENE AMPLIFICATION; GENE IDENTIFICATION; GENE LOCATION; GENE MAPPING; GENE SEQUENCE; INTRON; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DOMAIN; PROTEIN FOLDING; PROTOZOAL GENETICS; RNA SPLICING;

ALGORITHMS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; COMPUTATIONAL BIOLOGY; DNA, COMPLEMENTARY; EIMERIA TENELLA; EXONS; GENOME; INTRONS; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

EID: 34249713239     PISSN: 13866338     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W. and Lipman, D. J. (1997). Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res. 25 3389-3402.
2. Bankier, A. T., Spriggs, H. F., Fartmann, B., Konfortov, B. A., Madera, M., Vogel, C., Teichmann, S. A., Ivens, A. and Dear, P. H. (2003). Integrated mapping, chromosomal sequencing and sequence analysis of Cryptosporidium parvum. Genome Res. 13, 1787-1799.
3. Crooks, G. E., Hon, G., Chandonia, J. M. and Brenner, S. E. (2004). WebLogo: A sequence logo generator. Genome Res. 14, 1188-1190.
4. Fruman, D. A., Meyers, R. E. and Cantley, L. C. (1998). Phosphoinositide kinases. Annu. Rev. Biochem. 67, 481-507.
5. Gardner, M. J., Hall, N., Fung, E., White, O., Berriman, M., Hyman, R. W., Carlton, J. M., Pain, A., Nelson, K. E., Bowman, S., Paulsen, I. T., James, K., Eisen, J. A., Rutherford, K., Salzberg, S. L., Craig, A., Kyes, S., Chan, M. S., Nene, V., Shallom, S. J., Suh, B., Peterson, J., Angiuoli, S., Pertea, M., Allen, J., Selengut, J., Haft, D., Mather, M. W., Vaidya, A. B., Martin, D. M., Fairlamb, A. H., Fraunholz, M. J., Roos, D. S., Ralph, S. A., McFadden, G. I., Cummings, L. M., Subramanian, G. M., Mungall, C., Venter, J. C., Carucci, D. J., Hoffman, S. L., Newbold, C., Davis, R. W., Fraser, C. M. and Barrell, B. (2002). Genome sequence of the human malaria parasite Plasmodium falciparum Nature 419, 498-511.
6. Hall, N., Pain, A., Berriman, M., Churcher, C., Harris, B., Harris, D., Mungall, K., Bowman, S., Atkin, R., Baker, S., Barron, A., Brooks, K., Buckee, C. O., Burrows, C., Cherevach, I., Chillingworth, C., Chillingworth, T., Christodoulou, Z., Clark, L., Clark, R., Corton, C., Cronin, A., Davies, R., Davis, P., Dear, P., Dearden, F., Doggett, J., Feltwell, T., Goble, A., Goodhead, I., Gwilliam, R., Hamlin, N., Hance, Z., Harper, D., Hauser, H., Hornsby, T., Holroyd, S., Horrocks, P., Humphray, S., Jagels, K., James, K. D., Johnson, D., Kerhornou, A., Knights, A., Konfortov, B., Kyes, S., Larke, N., Lawson, D., Lennard, N., Line, A., Maddison, M., McLean, J., Mooney, P., Moule, S., Murphy, L., Oliver, K., Ormond, D., Price, C., Quail, M. A., Rabbinowitsch, E., Rajandream, M. A., Rutter, S., Rutherford, K. M., Sanders, M., Simmonds, M., Seeger, K., Sharp, S., Smith, R., Squares, R., Squares, S., Stevens, K., Taylor, K., Tivey, A., Unwin, L., Whitehead, S., Woodward, J., Sulston, J. E., Craig, A., Newbold, C. and Barrell, B. G. (2002). Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. Nature 419, 527-531.
7. Ishihara, H., Shibasaki, Y., Kizuki, N., Katagiri, H., Yazaki, Y., Asano, T. and Oka, Y. (1996). Cloning of cDNAs encoding two isoforms of 68-kDa type I phosphatidylinositol-4-phosphate 5-kinase. J. Biol. Chem. 271, 23611-23614.
8. Kunz, J., Wilson, M. P., Kisseleva, M., Hurley, J. H., Majerus, P. W. and Anderson, R. A. (2000). The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity. Mol. Cell. 5, 1-11.
9. Loijens, J. C. and Anderson, R. A. (1996). Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family. J. Biol. Chem. 271, 32937-32943.
10. Mount, S. M. (1982). A catalogue of splice junction sequences. Nucleic Acids Res. 10, 459-472.
11. Rameh, L. E., Tolias, K. F., Duckworth, B. C. and Cantley, L. C. (1997). A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate. Nature 390, 192-196.
12. Rutherford, K., Parkhill, J., Crook, J., Horsnell, T., Rice, P., Rajandream, M. A. and Barrell, B. (2000). Artemis: Sequence visualization and annotation. Bioinformatics 16, 944-945.
13. Staden, R., Beal, K. F. and Bonfield, J. K. (2000). The Staden package, 1998. Methods Mol. Biol. 132, 115-130.
14. Tolias, K. F., Rameh, L. E., Ishihara, H., Shibasaki, Y., Chen, J., Prestwich, G. D., Cantley, L. C. and Carpenter, C. L. (1998). Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 5-phosphate. J. Biol. Chem. 273, 18040-18046.
15. Tomley, F. M., Bumstead, J. M., Billington, K. J. and Dunn, P. P. (1996). Molecular cloning and characterization of a novel acidic microneme protein (Etmic-2) from the apicomplexan protozoan parasite, Eimeria tenella. Mol. Biochem. Parasitol. 79, 195-206.
16. Zhang, X., Loijens, J. C., Boronenkov, I. V., Parker, G. J., Norris, F. A., Chen, J., Thum, O., Prestwich, G. D., Majerus. P. W. and Anderson, R. A. (1997). Phosphatidylinositol-4-phosphate 5-kinase isozymes catalyze the synthesis of 3-phosphate-containing phosphatidylinositol signaling molecules. J. Biol. Chem. 272, 17756-17761.