Suppression of complement regulatory protein C1 inhibitor in vascular endothelial activation by inhibiting vascular cell adhesion molecule-1 action

Biochemical and Biophysical Research Communications

Volumn 358, Issue 4, 2007, Pages 1120-1127

  Zhang, Haimou ^a   Qin, Gangjian ^b   Liang, Gang ^c   Li, Jinan ^d   Chiu, Isaac ^d   Barrington, Robert A ^d   Liu, Dongxu ^a  

^a HUBEI UNIVERSITY   (China)

^b NORTHWESTERN UNIVERSITY   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Adhesion molecule; Complement; Endothelium; Signaling

Indexed keywords

COMPLEMENT COMPONENT C1S INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; REGULATOR PROTEIN; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL DAMAGE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; GENE ACTIVATION; GENE REPRESSION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; LEUKOCYTE ADHERENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RNA STABILITY; VASCULAR ENDOTHELIUM;

CELLS, CULTURED; COMPLEMENT C1 INACTIVATOR PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; HUMANS; LIPOPOLYSACCHARIDES; SERPINS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 34249705141     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.05.058     Document Type: Article

References (40)

1. Aird W.C. The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome. Blood 101 (2003) 3765-3777
2. Brandtzaeg P., Kierulf P., Gaustad P., Skulberg A., Bruun J.N., Halvorsen S., and Sorensen E. Plasma endotoxin as a predictor of multiple organ failure and death in systemic meningococcal disease. J. Infect. Dis. 159 (1989) 195-204
3. Cines D.B., Pollak E.S., Buck C.A., Loscalzo J., Zimmerman G.A., McEver R.P., Pober J.S., Wick T.M., Konkle B.A., Schwartz B.S., Barnathan E.S., McCrae K.R., Hug B.A., Schmidt A.M., and Stern D.M. Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood 91 (1998) 3527-3561
4. Goldblum S.E., Ding X., Brann T.W., and Campbell-Washington J. Bacterial lipopolysaccharide induces actin reorganization, intercellular gap formation, and endothelial barrier dysfunction in pulmonary vascular endothelial cells: concurrent F-actin depolymerization and new actin synthesis. J. Cell Physiol. 157 (1993) 13-23
5. Bannerman D.D., and Goldblum S.E. Mechanisms of bacterial lipopolysaccharide-induced endothelial apoptosis. Am. J. Physiol. Lung Cell Mol. Physiol. 284 (2003) L899-L914
6. Thijs L.G., Groeneveld A.B., and Hack C.E. Multiple organ failure in septic shock. Curr. Top Microbiol. Immunol. 216 (1996) 209-237
7. Bannerman D.D., Tupper J.C., Ricketts W.A., Bennett C.F., Winn R.K., and Harlan J.M. A constitutive cytoprotective pathway protects endothelial cells from lipopolysaccharide-induced apoptosis. J. Biol. Chem. 276 (2001) 14924-14932
8. Simoncini T., Maffei S., and Basta G. Estrogens and glucocorticoids inhibit endothelial vascular cell adhesion molecule-1 expression by different transcriptional mechanisms. Circ. Res. 87 (2000) 19-25
9. Dauphinee S.M., and Karsan A. Lipopolysaccharide signaling in endothelial cells. Lab. Invest. 86 (2006) 9-22
10. Sim R.B., Reboul A., Arlaud G.J., Villiers C.L., and Colomb M.G. Interaction of 125I-labelled complement subcomponents C-1r and C-1s with protease inhibitors in plasma. FEBS Lett. 97 (1979) 111-115
11. de Agostini A., Lijnen H.R., Pixley R.A., Colman R.W., and Schapira M. Inactivation of factor XII active fragment in normal plasma: Predominant role of C-1-inhibitor. J. Clin. Invest. 73 (1984) 1542-1549
12. Schapira M., Scott C.F., and Colman R.W. Contribution of plasma protease inhibitors to the inactivation of kallikrein in plasma. J. Clin. Invest. 69 (1982) 462-468
13. Czermak B.J., Sarma V., Pierson C.L., Warner R.L., Huber-Lang M., Bless N.M., Schmal H., Friedl H.P., and Ward P.A. Protective effects of C5a blockade in sepsis. Nat. Med. 5 (1999) 788-792
14. Caliezi C., Wuillemin W.A., Zeerleder S., Redondo M., Eisele B., and Hack C.E. C1-Esterase inhibitor: an anti-inflammatory agent and its potential use in the treatment of diseases other than hereditary angioedema. Pharmacol. Rev. 52 (2000) 91-112
15. Colman R.W. Biologic activities of the contact factors in vivo-potentiation of hypotension, inflammation, and fibrinolysis, and inhibition of cell adhesion, angiogenesis and thrombosis. Thromb. Haemost. 82 (1999) 1568-1577
16. Schmidt W., Stenzel K., Gebhard M.M., Martin E., and Schmidt H. C1-esterase inhibitor and its effects on endotoxin-induced leukocyte adherence and plasma extravasation in postcapillary venules. Surgery 125 (1999) 280-287
17. Croner R.S., Lehmann T.G., Fallsehr C., Herfarth C., Klar E., and Kirschfink M. C1-inhibitor reduces hepatic leukocyte-endothelial interaction and the expression of VCAM-1 in LPS-induced sepsis in the rat. Microvasc. Res. 67 (2004) 182-191
18. Liu D., Zhang D., Scafidi J., Wu X., Cramer C.C., and Davis III A.E. C1 inhibitor prevents Gram-negative bacterial lipopolysaccharide-induced vascular permeability. Blood 105 (2005) 2350-2355
19. Lawrence M.B., McIntire L.V., and Eskin S.G. Effect of flow on polymorphonuclear leukocyte/endothelial cell adhesion. Blood 70 (1987) 1284-1290
20. De Caterina R., Libby P., Peng H.B., Thannickal V.J., Rajavashisth T.B., Gimbrone Jr. M.A., Shin W.S., and Liao J.K. Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J. Clin. Invest. 96 (1995) 60-68
21. Tukey R.H., and Okino S.T. Quantitation of related gene products by nuclear run-on and Northern blot analysis. Methods Enzymol. 206 (1991) 284-290
22. Spiecker M., Darius H., Kaboth K., Hubner F., and Liao J.K. Differential regulation of endothelial cell adhesion molecule expression by nitric oxide donors and antioxidants. J. Leukoc. Biol. 63 (1998) 732-739
23. Carlos T.M., Schwartz B.R., Kovach N.L., Yee E., Rosa M., Osborn L., Chi-Rosso G., Newman B., and Lobb R. Vascular cell adhesion molecule-1 mediates lymphocyte adherence to cytokine-activated cultured human endothelial cells. Blood 76 (1990) 965-970
24. Masinovsky B., Urdal D., and Gallatin W.M. IL-4 acts synergistically with IL-1 beta to promote lymphocyte adhesion to microvascular endothelium by induction of vascular cell adhesion molecule-1. J. Immunol. 145 (1990) 2886-2895
25. Osborn L., Hession C., Tizard R., Vassallo C., Luhowskyj S., Chi-Rosso G., and Lobb R. Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes. Cell 59 (1989) 1203-1211
26. Tsai T.F., and Su T.S. A nuclear post-transcriptional event responsible for overproduction of argininosuccinate synthetase in a canavanine-resistant variant of a human epithelial cell line. Eur. J. Biochem. 229 (1995) 233-238
27. Yamamoto Y., and Gaynor R.B. IkappaB kinases: key regulators of the NF-kappaB pathway. Trends Biochem. Sci. 29 (2004) 72-79
28. Horstick G., Kempf T., Lauterbach M., Bhakdi S., Kopacz L., Heimann A., Malzahn M., Horstick M., Meyer J., and Kempski O. C1-esterase-inhibitor treatment at early reperfusion of hemorrhagic shock reduces mesentry leukocyte adhesion and rolling. Microcirculation 8 (2001) 427-433
29. Lehmann C., Birnbaum J., Luhrs C., Ruckbeil O., Spies C., Ziemer S., Grundling M., Pavlovic D., Usichenko T., Wendt M., and Kox W.J. Effects of C1 esterase inhibitor administration on intestinal functional capillary density, leukocyte adherence and mesenteric plasma extravasation during experimental endotoxemia. Intensive Care Med. 30 (2004) 309-314
30. Lehmann T.G., Heger M., Munch S., Kirschfink M., and Klar E. In vivo microscopy reveals that complement inhibition by C1-esterase inhibitor reduces ischemia/reperfusion injury in the liver. Transpl. Int. 13 (2000) S547-S550
31. Cai S., and Davis III A.E. Complement regulatory protein C1 inhibitor binds to selectins and interferes with endothelial-leukocyte adhesion. J. Immunol. 171 (2003) 4786-4791
32. Liu D., Cai S., Gu X., Scafidi J., Wu X., and Davis III A.E. C1 inhibitor prevents endotoxin shock via a direct interaction with lipopolysaccharide. J. Immunol. 171 (2003) 2594-2601
33. Haimovitz-Friedman A., Cordon-Cardo C., Bayoumy S., Garzotto M., McLoughlin M., Gallily R., Edwards C.K., Schuchman E.H., Fuks Z., and Kolesnick R. Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation. J. Exp. Med. 186 (1997) 1831-1841
34. Goldblum S.E., Brann T.W., Ding X., Pugin J., and Tobias P.S. Lipopolysaccharide (LPS)-binding protein and soluble CD14 function as accessory molecules for LPS-induced changes in endothelial barrier function, in vitro. J. Clin. Invest. 93 (1994) 692-702
35. Fujii E., Irie K., Ogawa A., Ohba K., and Muraki T. Role of nitric oxide and prostaglandins in lipopolysaccharide-induced increase in vascular permeability in mouse skin. Eur. J. Pharmacol. 297 (1996) 257-263
36. Aderem A., and Ulevitch R.J. Toll-like receptors in the induction of the innate immune response. Nature 406 (2000) 782-787
37. Weber K.S., Draude G., Erl W., de Martin R., and Weber C. Monocyte arrest and transmigration on inflamed endothelium in shear flow is inhibited by adenovirus-mediated gene transfer of IkappaB-alpha. Blood 93 (1999) 3685-3693
38. Brand K., Page S., Rogler G., Bartsch A., Brandl R., Knuechel R., Page M., Kaltschmidt C., Baeuerle P.A., and Neumeier D. Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J. Clin. Invest. 97 (1996) 1715-1722
39. Chen C.C., and Manning A.M. Transcriptional regulation of endothelial cell adhesion molecules: a dominant role for NF-kappa B. Agents Actions Suppl. 47 (1995) 135-141
40. Liu D., Cramer C.C., Scafidi J., and Davis III A.E. N-Linked glycosylation at Asn3 and the positively charged residues within the amino-terminal domain of the c1 inhibitor are required for interaction of the C1 Inhibitor with Salmonella enterica serovar typhimurium lipopolysaccharide and lipid A. Infect. Immun. 73 (2005) 4478-4487