Triptolide upregulates NGF synthesis in rat astrocyte cultures

Neurochemical Research

Volumn 32, Issue 7, 2007, Pages 1113-1119

  Xue, Bing ^a   Jiao, Jian ^a,c   Zhang, Lei ^b   Li, Kai Rong ^a   Gong, Yun Tao ^a   Xie, Jun Xia ^c   Wang, Xiao Min ^a,b  

^a PEKING UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c QINGDAO UNIVERSITY MEDICAL COLLEGE   (China)

Author keywords

Astrocyte; Brain derived neurotrophic factor; Glial cell line derived neurotrophic factor; Nerve growth factor; Triptolide

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR; TRIPTOLIDE;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL CULTURE; CELL LINE; CONTROLLED STUDY; CULTURE MEDIUM; GENE EXPRESSION; GLIA CELL; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN SYNTHESIS; RAT;

ANIMALS; ASTROCYTES; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; DITERPENES; DRUGS, CHINESE HERBAL; EPOXY COMPOUNDS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; IMMUNOSUPPRESSIVE AGENTS; MEDICINE, CHINESE TRADITIONAL; NERVE GROWTH FACTOR; PHENANTHRENES; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS; TRIPTERYGIUM WILFORDII;

EID: 34249695397     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-006-9253-1     Document Type: Article

References (25)

1. Zhao G, Vaszar LT, Qiu D, Shi L, Kao PN (2000) Anti-inflammatory effects of triptolide in human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol 279:L958-L966
2. Zheng YL, Lin JF, Lin CC, Xu Y (1994) [Anti-inflammatory effect of triptolide]. Zhongguo Yao Li Xue Bao 15:540-543
3. Li FQ, Cheng XX, Liang XB, Wang XH, Xue B, He QH, Wang XM, Han JS (2003) Neurotrophic and neuroprotective effects of tripchlorolide, an extract of Chinese herb Tripterygium wilfordii Hook F, on dopaminergic neurons. Exp Neurol 179:28-37
4. Zhou HF, Liu XY, Niu DB, Li FQ, He QH, Wang XM (2005) Triptolide protects dopaminergic neurons from inflammation-mediated damage induced by lipopolysaccharide intranigral injection. Neurobiol Dis 18:441-449
5. Siegel GJ, Chauhan NB (2000) Neurotrophic factors in Alzheimer's and Parkinson's disease brain. Brain Res Brain Res Rev 33:199-227
6. Bhat NR (1995) Signal transduction mechanisms in glial cells. Dev Neurosci 17:267-284
7. Kuno R, Yoshida Y, Nitta A, Nabeshima T, Wang J, Sonobe Y, Kawanokuchi J, Takeuchi H, Mizuno T, Suzumura A (2006) The role of TNF-alpha and its receptors in the production of NGF and GDNF by astrocytes. Brain Res 1116:12-18
8. Ridet JL, Malhotra SK, Privat A, Gage FH (1997) Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci 20:570-577
9. Petrova PS, Raibekas A, Pevsner J, Vigo N, Anafi M, Moore MK, Peaire A, Shridhar V, Smith DI, Kelly J, Durocher Y, Commissiong JW (2004) Discovering novel phenotype-selective neurotrophic factors to treat neurodegenerative diseases. Prog Brain Res 146:168-183
10. Miyazaki H, Nagashima K, Okuma Y, Nomura Y (2001) Expression of glial cell line-derived neurotrophic factor induced by transient forebrain ischemia in rats. Brain Res 922:165-172
11. Semkova I, Wolz P, Schilling M, Krieglstein J (1996) Selegiline enhances NGF synthesis and protects central nervous system neurons from excitotoxic and ischemic damage. Eur J Pharmacol 315:19-30
12. Zafra F, Lindholm D, Castren E, Hartikka J, Thoenen H (1992) Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes. J Neurosci 12:4793-4799
13. Miklic S, Juric DM, Carman-Krzan M (2004) Differences in the regulation of BDNF and NGF synthesis in cultured neonatal rat astrocytes. Int J Dev Neurosci 22:119-130
14. Pshenichkin SP, Wise BC (1995) Okadaic acid increases nerve growth factor secretion, mRNA stability, and gene transcription in primary cultures of cortical astrocytes. J Biol Chem 270:5994-5999
15. D'Mello SR, Heinrich G (1990) Induction of nerve growth factor gene expression by 12-O-tetradecanoyl phorbol 13-acetate. J Neurochem 55:718-721
16. Galve-Roperh I, Haro A, az-Laviada I (1997) Induction of nerve growth factor synthesis by sphingomyelinase and ceramide in primary astrocyte cultures. Brain Res Mol Brain Res 52:90-97
17. Galve-Roperh I, Malpartida JM, Haro A, Brachet P, az-Laviada I (1997) Regulation of nerve growth factor secretion and mRNA expression by bacterial lipopolysaccharide in primary cultures of rat astrocytes. J Neurosci Res 49:569-575
18. Tang LL, Wang R, Tang XC (2005) Huperzine A protects SHSY5Y neuroblastoma cells against oxidative stress damage via nerve growth factor production. Eur J Pharmacol 519:9-15
19. Lad SP, Neet KE, Mufson EJ (2003) Nerve growth factor: structure, function and therapeutic implications for Alzheimer's disease. Curr Drug Targets CNS Neurol Disord 2:315-334
20. Weis C, Marksteiner J, Humpel C (2001) Nerve growth factor and glial cell line-derived neurotrophic factor restore the cholinergic neuronal phenotype in organotypic brain slices of the basal nucleus of Meynert. Neuroscience 102:129-138
21. Hefti F (1986) Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections. J Neurosci 6:2155-2162
22. Tuszynski MH, HS U, Amaral DG, Gage FH (1990) Nerve growth factor infusion in the primate brain reduces lesion-induced cholinergic neuronal degeneration. J Neurosci 10:3604-3614
23. Tuszynski MH, Sang H, Yoshida K, Gage FH (1991) Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain. Ann Neurol 30:625-636
24. Seiger A, Nordberg A, von HH, Backman L, Ebendal T, Alafuzoff I, Amberla K, Hartvig P, Herlitz A, Lilja A (1993) Intracranial infusion of purified nerve growth factor to an Alzheimer patient: the first attempt of a possible future treatment strategy. Behav. Brain Res 57:255-261
25. Saito M, Hori M, Obara Y, Ohizumi Y, Ohkubo S, Nakahata N (2006) Neurotrophic factor production in human astrocytoma cells by 2,5,6-tribromogramine via activation of epsilon isoform of protein kinase C. Eur J Pharm Sci 28:263-271