Quantitative analysis of Tenecteplase in rat plasma samples using LC-MS/MS as an alternative for ELISA

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 852, Issue 1-2, 2007, Pages 631-634

  Buscher, B A P ^a   Gerritsen, H ^a   van Scholl I ^a   Cnubben, N H P ^a   Brull L P ^a  

^a TNO   (Netherlands)

Author keywords

Digestion; Liquid chromatography; Mass spectrometry; Plasma; Proteins; Quantitative analysis

Indexed keywords

BLOOD; DIGESTIVE SYSTEM; DRUG PRODUCTS; ENZYMES; SENSITIVITY ANALYSIS;

INTERNAL STANDARD; TENECTEPLASE; TRYPSIN;

CHEMICAL ANALYSIS;

TENECTEPLASE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG DISTRIBUTION; ENZYME LINKED IMMUNOSORBENT ASSAY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SINGLE DRUG DOSE;

ANIMALS; CHROMATOGRAPHY, LIQUID; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBRINOLYTIC AGENTS; RATS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TISSUE PLASMINOGEN ACTIVATOR;

RATTUS;

EID: 34249686605     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2006.12.053     Document Type: Article

References (14)

1. Shi Y., Xiang R., Horvath C., and Wilkins J.A. J. Chromatogr. A 1053 (2004) 27
2. Wysocki V.H., Resing K.A., Zhang Q., and Cheng G. Methods 35 (2005) 211
3. Higgs R.E., Knierman M.D., Gelfanova V., Butler J.P., and Hale J.E. J. Proteome Res. 4 (2005) 1442
4. Flory M.R., Griffing T.J., Martin D., and Aebersold R. Trends Biotechnol. 20 12 (2002) 23
5. Meehan K.L., and Sadar M.D. Proteomics 4 (2004) 1116
6. Lee Y.H., Han H., Chang S.-B., and Lee S.-W. Rapid Commun. Mass Spectrom. 18 (2004) 3019
7. Lee Y.H., Kim M.-S., Choie W.-S., Min H.-K., and Lee S.-W. Proteomics 4 (2004) 1684
8. Brancia F.L., Montgomery H., Tanaka K., and Kumashiro S. Anal. Chem. 76 (2004) 2748
9. Chakraborty A., and Regnier F.E. J. Chromatogr. A 949 (2002) 173
10. Goodlett D.R., Keller A., Watts J.D., Newitt R., Yi E.C., Purvine S., Eng J.K., von Haller P., Aebersold R., and Kolker E. Rapid Commun. Mass Spectrom. 15 (2001) 1214
11. Ji Q.C., Rodila R., Gage E.M., and El-Shourbagy T.A. Anal. Chem. 75 (2003) 7008
12. Kirkpatrick D.S., Gerber S.A., and Gygi S.P. Methods 35 (2005) 265
13. Gerber S.A., Rush J., Stemman O., Kirschner M.W., and Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 6940
14. Chelius D., and Bondarenko P.V. J. Proteome Res. 1 (2002) 317