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Volumn 25, Issue 3, 2007, Pages 259-266

The potential antioxidant effect of raloxifene treatment: A study on heart, liver and brain cortex of ovariectomized female rats

Author keywords

Antioxidant enzymes; Glutathione; Lipid peroxidation; Ovariectomy; Raloxifene; Selective estrogen receptor modulators

Indexed keywords

CARBOXYMETHYLCELLULOSE; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; RALOXIFENE; SUPEROXIDE DISMUTASE; THIOREDOXIN REDUCTASE;

EID: 34249681382     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.1328     Document Type: Article
Times cited : (33)

References (37)
  • 3
    • 0038345232 scopus 로고    scopus 로고
    • The effects of estrogen and raloxifene treatment on antioxidant enzymes in brain and liver of ovarectomized female rats
    • Ozgonul M, Oge A, Sezer ED, Bayraktar F, Sozmen EY. The effects of estrogen and raloxifene treatment on antioxidant enzymes in brain and liver of ovarectomized female rats. Endocr Res 2003; 29: 183-189.
    • (2003) Endocr Res , vol.29 , pp. 183-189
    • Ozgonul, M.1    Oge, A.2    Sezer, E.D.3    Bayraktar, F.4    Sozmen, E.Y.5
  • 4
    • 0035107002 scopus 로고    scopus 로고
    • Effects of SERMs on important indicators of cardiovascular health: Lipoproteins, hemostatic factors, endothelial function
    • Herrington DM, Klein KP. Effects of SERMs on important indicators of cardiovascular health: lipoproteins, hemostatic factors, endothelial function. Womens Health Issues 2001; 11: 95-102.
    • (2001) Womens Health Issues , vol.11 , pp. 95-102
    • Herrington, D.M.1    Klein, K.P.2
  • 5
    • 13944274553 scopus 로고    scopus 로고
    • Effects of raloxifene on serum malondialdehyde, erythrocyte superoxide dismutase, and erythrocyte glutathione peroxidase levels in healthy postmenopausal women
    • Kaya H, Ozkaya O, Sezik M, Arslanoglu E, Yilmaztepe A, Ulukaya E. Effects of raloxifene on serum malondialdehyde, erythrocyte superoxide dismutase, and erythrocyte glutathione peroxidase levels in healthy postmenopausal women. Maturitas 2005; 50: 182-188.
    • (2005) Maturitas , vol.50 , pp. 182-188
    • Kaya, H.1    Ozkaya, O.2    Sezik, M.3    Arslanoglu, E.4    Yilmaztepe, A.5    Ulukaya, E.6
  • 6
    • 33044494094 scopus 로고    scopus 로고
    • A systematic review and economic evaluation of alendronate, etidronate, risedronate, raloxifene and teriparatide for the prevention and treatment of postmenopausal osteoporosis
    • Stevenson M, Lloyd Jones M, De Nigris E, Brewer N, Davis S, Oakley J. A systematic review and economic evaluation of alendronate, etidronate, risedronate, raloxifene and teriparatide for the prevention and treatment of postmenopausal osteoporosis. Health Technol Assess 2005; 9: 1-160.
    • (2005) Health Technol Assess , vol.9 , pp. 1-160
    • Stevenson, M.1    Lloyd Jones, M.2    De Nigris, E.3    Brewer, N.4    Davis, S.5    Oakley, J.6
  • 8
    • 0030775052 scopus 로고    scopus 로고
    • In search of optimal long-term female estrogen replacement: The potential of selective estrogen receptor modulators
    • Mitlak BH, Cohen FJ. In search of optimal long-term female estrogen replacement: the potential of selective estrogen receptor modulators. Hor Res 1997; 48: 155-163.
    • (1997) Hor Res , vol.48 , pp. 155-163
    • Mitlak, B.H.1    Cohen, F.J.2
  • 9
    • 0032787158 scopus 로고    scopus 로고
    • The selective estrogen receptor modulation: Evaluation and clinical application
    • Purdie DW, Beardsworth SA. The selective estrogen receptor modulation: evaluation and clinical application. Br J Clin Pharmacol 1999; 48: 785-792.
    • (1999) Br J Clin Pharmacol , vol.48 , pp. 785-792
    • Purdie, D.W.1    Beardsworth, S.A.2
  • 10
    • 0030664688 scopus 로고    scopus 로고
    • Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium is postmenopausal women
    • Delmas PD, Bjarnason NH, Mitlak BH, et al. Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium is postmenopausal women. N Eng J Med 1997; 337: 1641-1647.
    • (1997) N Eng J Med , vol.337 , pp. 1641-1647
    • Delmas, P.D.1    Bjarnason, N.H.2    Mitlak, B.H.3
  • 11
    • 0030605162 scopus 로고    scopus 로고
    • Enhanced oxidative stress in female rat brain after gonadectomy
    • Kume-Kick J, Ferris DC, Russo-Menna I, Rice ME. Enhanced oxidative stress in female rat brain after gonadectomy. Brain Res 1996; 738: 8-14.
    • (1996) Brain Res , vol.738 , pp. 8-14
    • Kume-Kick, J.1    Ferris, D.C.2    Russo-Menna, I.3    Rice, M.E.4
  • 12
    • 0042266785 scopus 로고    scopus 로고
    • Modulation of antioxidant enzyme expression and function by estrogen
    • Strehlow K, Rotter S, Wassmann S, et al. Modulation of antioxidant enzyme expression and function by estrogen. Circ Res 2003; 93: 170-177.
    • (2003) Circ Res , vol.93 , pp. 170-177
    • Strehlow, K.1    Rotter, S.2    Wassmann, S.3
  • 13
    • 8244264298 scopus 로고    scopus 로고
    • Hypercholesterolemic activity of raloxifene (LY139481): Pharmacological characterzation as a selective estrogen receptor modulator
    • Kauffman RF, Bensch WR, Roudebush RE, et al. Hypercholesterolemic activity of raloxifene (LY139481): Pharmacological characterzation as a selective estrogen receptor modulator. J Pharmacol ExpTher 1997; 280(1): 146-153.
    • (1997) J Pharmacol ExpTher , vol.280 , Issue.1 , pp. 146-153
    • Kauffman, R.F.1    Bensch, W.R.2    Roudebush, R.E.3
  • 15
    • 0030020576 scopus 로고    scopus 로고
    • A new selenoprotein from human lung adenocarcinoma cells: Purification, properties, and thioredoxin reductase activity
    • Tamura T, Stadtman TC. A new selenoprotein from human lung adenocarcinoma cells: purification, properties, and thioredoxin reductase activity. Proc Natl Acad Sci USA 1996; 93: 1006-1011.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1006-1011
    • Tamura, T.1    Stadtman, T.C.2
  • 16
    • 2942612996 scopus 로고    scopus 로고
    • Modulation of IL-1 beta gene expression by lipid peroxidation inhibition after kainic acid-induced rat brain injury
    • Marini H, Altavilla D, Bellomo M, et al. Modulation of IL-1 beta gene expression by lipid peroxidation inhibition after kainic acid-induced rat brain injury. Exp Neurol 2004; 188: 178-186.
    • (2004) Exp Neurol , vol.188 , pp. 178-186
    • Marini, H.1    Altavilla, D.2    Bellomo, M.3
  • 17
    • 0018079943 scopus 로고
    • Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method
    • Satoh K. Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method. Clin Chim Acta 1978; 90: 37-43.
    • (1978) Clin Chim Acta , vol.90 , pp. 37-43
    • Satoh, K.1
  • 18
    • 0021288840 scopus 로고
    • LPO assay for blood plasma or serum
    • Yagi K. LPO assay for blood plasma or serum. Meths Enzymol 1984; 105: 328-331.
    • (1984) Meths Enzymol , vol.105 , pp. 328-331
    • Yagi, K.1
  • 20
    • 0026458371 scopus 로고
    • Hormone therapy to prevent disease and prolong life in postmenopausal women
    • Grady D, Rubin SM, Petitti DB, et al. Hormone therapy to prevent disease and prolong life in postmenopausal women. Ann Intern Med 1992; 117: 1016-1037.
    • (1992) Ann Intern Med , vol.117 , pp. 1016-1037
    • Grady, D.1    Rubin, S.M.2    Petitti, D.B.3
  • 21
    • 0030610461 scopus 로고    scopus 로고
    • Postmenopausal hormone therapy and mortality
    • Grodstein F, Stampfer MJ, Colditz GA, et al. Postmenopausal hormone therapy and mortality. N Engl J Med 1997; 336: 1769-1775.
    • (1997) N Engl J Med , vol.336 , pp. 1769-1775
    • Grodstein, F.1    Stampfer, M.J.2    Colditz, G.A.3
  • 22
    • 0030748719 scopus 로고    scopus 로고
    • A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: The Baltimore Longitudinal Study of Aging
    • Kawas C, Resnick S, Morrison A, et al. A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: the Baltimore Longitudinal Study of Aging. Neurology 1997; 48: 1517-1521.
    • (1997) Neurology , vol.48 , pp. 1517-1521
    • Kawas, C.1    Resnick, S.2    Morrison, A.3
  • 23
    • 16344390950 scopus 로고    scopus 로고
    • Vascular consequences of menopause and hormone therapy: Importance of timing of treatment and type of estrogen
    • Dubey RK, Imthurn B, Barton M, Jackson EK. Vascular consequences of menopause and hormone therapy: importance of timing of treatment and type of estrogen. Cardiovasc Res 2005; 66: 295-306.
    • (2005) Cardiovasc Res , vol.66 , pp. 295-306
    • Dubey, R.K.1    Imthurn, B.2    Barton, M.3    Jackson, E.K.4
  • 25
    • 4644305196 scopus 로고    scopus 로고
    • Modulation of oxidation and antioxidant enzyme expression and function in vascular cells
    • Wassmann S, Wassmann K, Nickenig G. Modulation of oxidation and antioxidant enzyme expression and function in vascular cells. Hypertension 2004; 44: 381-386.
    • (2004) Hypertension , vol.44 , pp. 381-386
    • Wassmann, S.1    Wassmann, K.2    Nickenig, G.3
  • 26
    • 0034070228 scopus 로고    scopus 로고
    • Protective effect of estrogens against oxidative damage to heart and skeletal muscle in vivo and in vitro
    • Persky AM, Green PS, Stubley L, et al. Protective effect of estrogens against oxidative damage to heart and skeletal muscle in vivo and in vitro. Proc Soc Exp Biol Med 2000; 223: 59-66.
    • (2000) Proc Soc Exp Biol Med , vol.223 , pp. 59-66
    • Persky, A.M.1    Green, P.S.2    Stubley, L.3
  • 27
    • 0033674296 scopus 로고    scopus 로고
    • 17-beta-estradiol prevents oxidative stress and decreases blood pressure in ovariectomized rats
    • Hernandez I, Delgado JL, Diaz J, et al. 17-beta-estradiol prevents oxidative stress and decreases blood pressure in ovariectomized rats. Am J Physiol Regul Integr Comp Physiol 2000; 279: 1599-1605.
    • (2000) Am J Physiol Regul Integr Comp Physiol , vol.279 , pp. 1599-1605
    • Hernandez, I.1    Delgado, J.L.2    Diaz, J.3
  • 29
    • 13844267505 scopus 로고    scopus 로고
    • Effects of 17-beta estradiol on cerebral ischaemic damage and lipid peroxidation
    • Gordon KB, Macrae IM, Carswell HV. Effects of 17-beta estradiol on cerebral ischaemic damage and lipid peroxidation. Brain Res 2005; 1036: 155-162.
    • (2005) Brain Res , vol.1036 , pp. 155-162
    • Gordon, K.B.1    Macrae, I.M.2    Carswell, H.V.3
  • 30
    • 0036971481 scopus 로고    scopus 로고
    • Estrogenic properties of raloxifene, but not tamoxifene, on D2 and D3 dopamine receptors in the rat forebrain
    • Landry M, Levesque D, Di Paolo T. Estrogenic properties of raloxifene, but not tamoxifene, on D2 and D3 dopamine receptors in the rat forebrain. Neuroendocrinology 2002; 76: 214-222.
    • (2002) Neuroendocrinology , vol.76 , pp. 214-222
    • Landry, M.1    Levesque, D.2    Di Paolo, T.3
  • 31
    • 0034989986 scopus 로고    scopus 로고
    • Estrogen like activity of tamoxifen and raloxifen on NMDA receptor binding and expression of subunits in rat brain
    • Cyr M, Thibault C, Morissette M, Landry M, Di Paolo T. Estrogen like activity of tamoxifen and raloxifen on NMDA receptor binding and expression of subunits in rat brain. Neuropsychopharmacology 2001; 25: 242-257.
    • (2001) Neuropsychopharmacology , vol.25 , pp. 242-257
    • Cyr, M.1    Thibault, C.2    Morissette, M.3    Landry, M.4    Di Paolo, T.5
  • 32
    • 0036159571 scopus 로고    scopus 로고
    • Selective estrogen receptor modulator effects in the rat brain
    • Zhou W, Koldzic-Zivanovic N, Clarke CH, et al. Selective estrogen receptor modulator effects in the rat brain. Neuroendocrinology 2002; 75(1): 24-33.
    • (2002) Neuroendocrinology , vol.75 , Issue.1 , pp. 24-33
    • Zhou, W.1    Koldzic-Zivanovic, N.2    Clarke, C.H.3
  • 34
    • 0347624528 scopus 로고    scopus 로고
    • Impact of the selective estrogen receptor modulator, raloxifene, on neuronal survival and outhgrowth following toxic insults associated with aging and Alzheimer 's disease
    • O'Neill K, Chen S, Brinton RD. Impact of the selective estrogen receptor modulator, raloxifene, on neuronal survival and outhgrowth following toxic insults associated with aging and Alzheimer 's disease. Exp Neurol 2004; 185: 63-80.
    • (2004) Exp Neurol , vol.185 , pp. 63-80
    • O'Neill, K.1    Chen, S.2    Brinton, R.D.3
  • 35
    • 22644439854 scopus 로고    scopus 로고
    • Altered level of apurinic/apyrimidinic endonuclease/redox factor-1 (APE/Ref-1) mRNA in the hippocampus of ovariectomized rats treated by raloxifene against kainic acid
    • Yalcin A, Kanit L, Durmaz G, Sargin S, Terek CH, Tanyolac B. Altered level of apurinic/apyrimidinic endonuclease/redox factor-1 (APE/Ref-1) mRNA in the hippocampus of ovariectomized rats treated by raloxifene against kainic acid. Clin Exp Pharm Physiol 2005; 32: 611-614.
    • (2005) Clin Exp Pharm Physiol , vol.32 , pp. 611-614
    • Yalcin, A.1    Kanit, L.2    Durmaz, G.3    Sargin, S.4    Terek, C.H.5    Tanyolac, B.6
  • 36
    • 12244279556 scopus 로고    scopus 로고
    • The effects of estrogen and raloxifene treatment on the antioxidant enzymes and nitrite-nitrate levels in brain cortex of ovariectomized rats
    • Oge A, Sezer ED, Ozgonul M, Bayraktar F, Sozmen EY. The effects of estrogen and raloxifene treatment on the antioxidant enzymes and nitrite-nitrate levels in brain cortex of ovariectomized rats. Neurosci Lett 2003; 338: 217-220.
    • (2003) Neurosci Lett , vol.338 , pp. 217-220
    • Oge, A.1    Sezer, E.D.2    Ozgonul, M.3    Bayraktar, F.4    Sozmen, E.Y.5
  • 37
    • 0037606188 scopus 로고    scopus 로고
    • Induction of antioxidative and antiapoptotic thioredoxin supports neuroprotective hypothesis of estrogen
    • Chiueh C, Lee S, Andoh T, Murphy D. Induction of antioxidative and antiapoptotic thioredoxin supports neuroprotective hypothesis of estrogen. Endocrine 2003; 21: 27-31.
    • (2003) Endocrine , vol.21 , pp. 27-31
    • Chiueh, C.1    Lee, S.2    Andoh, T.3    Murphy, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.