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Volumn 85, Issue 2, 2007, Pages 196-202

Anti-CD3 scFv-B7.1 fusion protein expressed on the surface of HeLa cells provokes potent T-lymphocyte activation and cytotoxicity

Author keywords

Anti CD3 scFv; B7.1; Biological activity; Eukaryotic expression; Fusion protein; HeLa cells

Indexed keywords

BIOTHERAPY; ELECTROPORATION; EUKARYOTIC EXPRESSION; HELA CELLS;

EID: 34249675795     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/O07-013     Document Type: Conference Paper
Times cited : (4)

References (32)
  • 1
    • 0032960247 scopus 로고    scopus 로고
    • B7-1 gene-modified tumor cell vaccines
    • Antonia, S.J. 1999. B7-1 gene-modified tumor cell vaccines. Curr. Opin. Mol. Ther. 1: 50-56.
    • (1999) Curr. Opin. Mol. Ther , vol.1 , pp. 50-56
    • Antonia, S.J.1
  • 2
    • 13844296952 scopus 로고    scopus 로고
    • A novel bispecific tetravalent antibody fusion protein to target costimulatory activity for T-cell activation to tumor cells overexpressing ErbB2/ HER2
    • doi:10.1016/j.jmb.2004. 12.052
    • Biburger, M., Weth, R., and Weis, W.S. 2005. A novel bispecific tetravalent antibody fusion protein to target costimulatory activity for T-cell activation to tumor cells overexpressing ErbB2/ HER2. J. Mol. Biol. 346: 1299-1311. doi:10.1016/j.jmb.2004. 12.052.
    • (2005) J. Mol. Biol , vol.346 , pp. 1299-1311
    • Biburger, M.1    Weth, R.2    Weis, W.S.3
  • 3
    • 0026044914 scopus 로고
    • T cell targeting in cancer therapy
    • doi:10.1007/ BF01741317
    • Bolhuis, R.L., Sturm, E., and Braakman, E. 1991. T cell targeting in cancer therapy. Cancer Immunol. Immunother. 34: 1-8. doi:10.1007/ BF01741317.
    • (1991) Cancer Immunol. Immunother , vol.34 , pp. 1-8
    • Bolhuis, R.L.1    Sturm, E.2    Braakman, E.3
  • 4
    • 0037375525 scopus 로고    scopus 로고
    • Tumour immunology
    • doi:10.1016/S0952-7915(03)00010-4
    • Boon, T., and Van den Eynde, B. 2003. Tumour immunology. Curr. Opin. Immunol. 15: 129-130. doi:10.1016/S0952-7915(03)00010-4.
    • (2003) Curr. Opin. Immunol , vol.15 , pp. 129-130
    • Boon, T.1    Van den Eynde, B.2
  • 5
    • 0026541544 scopus 로고
    • The two-signal model of lymphocyte activation twenty-one years later
    • doi:10. 1016/0167-5699(92)90138-W
    • Bretscher, P. 1992. The two-signal model of lymphocyte activation twenty-one years later. Immunol. Today, 13: 74-76. doi:10. 1016/0167-5699(92)90138-W.
    • (1992) Immunol. Today , vol.13 , pp. 74-76
    • Bretscher, P.1
  • 6
    • 0032055860 scopus 로고    scopus 로고
    • A B7.1-antibody fusion protein retains antibody specificity and ability to activate via the T cell costimulatory pathway
    • Challita-Eid, P.M., Penichet, M.L., Shin, S.U., Poles, T., Mosammaparast, N., Mahmood, K., et al. 1998. A B7.1-antibody fusion protein retains antibody specificity and ability to activate via the T cell costimulatory pathway. J. Immunol. 160: 3419-3426.
    • (1998) J. Immunol , vol.160 , pp. 3419-3426
    • Challita-Eid, P.M.1    Penichet, M.L.2    Shin, S.U.3    Poles, T.4    Mosammaparast, N.5    Mahmood, K.6
  • 7
    • 2942520109 scopus 로고    scopus 로고
    • Tumor-targeted gene delivery via anti-HER2 antibody (trastuzumab, Herceptin) conjugated polyethylenimine
    • doi:10.1016/j.jconrel.2004.03.019
    • Chiu, S.J., Ueno, N.T., and Lee, R.J. 2004. Tumor-targeted gene delivery via anti-HER2 antibody (trastuzumab, Herceptin) conjugated polyethylenimine. J. Control. Release, 97: 357-369. doi:10.1016/j.jconrel.2004.03.019.
    • (2004) J. Control. Release , vol.97 , pp. 357-369
    • Chiu, S.J.1    Ueno, N.T.2    Lee, R.J.3
  • 8
    • 0345363251 scopus 로고    scopus 로고
    • Apoptosis of a human melanoma cell line specifically induced by membrane-bound single-chain antibodies
    • de Ines, C., Cochlovius, B., Schmidt, S., Kipriyanov, S., Rode, H.J., and Little, M. 1999. Apoptosis of a human melanoma cell line specifically induced by membrane-bound single-chain antibodies. J. Immunol. 163: 3948-3956.
    • (1999) J. Immunol , vol.163 , pp. 3948-3956
    • de Ines, C.1    Cochlovius, B.2    Schmidt, S.3    Kipriyanov, S.4    Rode, H.J.5    Little, M.6
  • 10
    • 0037143806 scopus 로고    scopus 로고
    • Extremely potent, rapid and costimulation-independent cytotoxic T-cell response against lymphoma cells catalyzed by a single-chain bispecific antibody
    • doi:10.1002/ijc.10557
    • Dreier, T., Lorenczewski, G., Brandi, C., Hoffmann, P., Syring, U., Hanakam, F., et al. 2002. Extremely potent, rapid and costimulation-independent cytotoxic T-cell response against lymphoma cells catalyzed by a single-chain bispecific antibody. Int. J. Cancer, 100: 690-697. doi:10.1002/ijc.10557.
    • (2002) Int. J. Cancer , vol.100 , pp. 690-697
    • Dreier, T.1    Lorenczewski, G.2    Brandi, C.3    Hoffmann, P.4    Syring, U.5    Hanakam, F.6
  • 11
    • 0036852241 scopus 로고    scopus 로고
    • Cancer immunoediting: From immunosurveillance to tumor escape
    • doi:10.1038/ni1102-991
    • Dunn, G.P., Bruce, A.T., Ikeda, H., Old, L.J., and Schreiber, R.D. 2002. Cancer immunoediting: from immunosurveillance to tumor escape. Nat. Immunol. 3: 991-998. doi:10.1038/ni1102-991.
    • (2002) Nat. Immunol , vol.3 , pp. 991-998
    • Dunn, G.P.1    Bruce, A.T.2    Ikeda, H.3    Old, L.J.4    Schreiber, R.D.5
  • 12
    • 0036272792 scopus 로고    scopus 로고
    • Immunologic mechanisms of antitumor activity
    • doi:10.1053/sonc.2002.33076
    • Foss, F.M. 2002. Immunologic mechanisms of antitumor activity. Semin. Oncol. 29: 5-11. doi:10.1053/sonc.2002.33076.
    • (2002) Semin. Oncol , vol.29 , pp. 5-11
    • Foss, F.M.1
  • 13
    • 33846818556 scopus 로고    scopus 로고
    • Pulmonary adenocarcinoma-targeted gene therapy by a cancer- and tissue-specific promoter system
    • doi:10.1158/1535-7163.MCT-06-0408
    • Fukazawa, T., Maeda, Y., Durbin, M.L., Nakai, T., Matsuoka, J., Tanaka, H., Naomoto, Y., and Tanaka, N. 2007. Pulmonary adenocarcinoma-targeted gene therapy by a cancer- and tissue-specific promoter system. Mol. Cancer Ther. 6: 244-252. doi:10.1158/1535-7163.MCT-06-0408.
    • (2007) Mol. Cancer Ther , vol.6 , pp. 244-252
    • Fukazawa, T.1    Maeda, Y.2    Durbin, M.L.3    Nakai, T.4    Matsuoka, J.5    Tanaka, H.6    Naomoto, Y.7    Tanaka, N.8
  • 14
    • 0141761508 scopus 로고    scopus 로고
    • Tumor escape from immune response: Mechanisms and targets of activity
    • doi: 10.2174/1389450033490849
    • Gabrilovich, D., and Pisarev, V. 2003. Tumor escape from immune response: mechanisms and targets of activity. Curr. Drug Targets, 4: 525-536. doi: 10.2174/1389450033490849.
    • (2003) Curr. Drug Targets , vol.4 , pp. 525-536
    • Gabrilovich, D.1    Pisarev, V.2
  • 15
    • 13544257458 scopus 로고    scopus 로고
    • Tumor cell targeted gene delivery by adenovirus 5 vectors carrying knobless fibers with antibody-binding domains
    • doi:10.1038/sj. gt.3302408
    • Henning, P., Andersson, K.M., Frykholm, K., Ali, A., Magnusson, M.K., Nygren, P.A., et al. 2005. Tumor cell targeted gene delivery by adenovirus 5 vectors carrying knobless fibers with antibody-binding domains. Gene Ther. 12: 211-224. doi:10.1038/sj. gt.3302408.
    • (2005) Gene Ther , vol.12 , pp. 211-224
    • Henning, P.1    Andersson, K.M.2    Frykholm, K.3    Ali, A.4    Magnusson, M.K.5    Nygren, P.A.6
  • 16
    • 0025294857 scopus 로고
    • Evaluation of tetrazolium-based semiautomatic colorimetric assay for measurement of human antitumor cytotoxicity
    • Heo, D.S., Park, J.G., Hata, K., Day, R., Herberman, R.B., and Whiteside, T.L. 1990. Evaluation of tetrazolium-based semiautomatic colorimetric assay for measurement of human antitumor cytotoxicity. Cancer Res. 50: 3681-3690.
    • (1990) Cancer Res , vol.50 , pp. 3681-3690
    • Heo, D.S.1    Park, J.G.2    Hata, K.3    Day, R.4    Herberman, R.B.5    Whiteside, T.L.6
  • 17
    • 0035371903 scopus 로고    scopus 로고
    • Hoffmann, P., Mueller, N., Shively, J.E., Fleischer, B., and Neumaier, M. 2001. Fusion proteins of B7.1 and a carcinoembryonic antigen (CEA)-specific antibody fragment opsonize CEA-expressing tumor cells and coactivate T-cell immunity. Int. J. Cancer, 92: 725-732. doi:10.1002/1097-0215(20010601) 92:5〈725::AID-IJC1252〉3.0.CO;2-S.
    • Hoffmann, P., Mueller, N., Shively, J.E., Fleischer, B., and Neumaier, M. 2001. Fusion proteins of B7.1 and a carcinoembryonic antigen (CEA)-specific antibody fragment opsonize CEA-expressing tumor cells and coactivate T-cell immunity. Int. J. Cancer, 92: 725-732. doi:10.1002/1097-0215(20010601) 92:5〈725::AID-IJC1252〉3.0.CO;2-S.
  • 18
    • 0024556150 scopus 로고
    • Engineering hybrid genes without the use of restriction enzymes: Gene splicing by overlap extension
    • doi:10.1016/0378-1119(89)90359-4
    • Horton, R.M., Hunt, H.D., Ho, S.N., Pullen, J.K., and Pease, L.R. 1989. Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension. Gene, 77: 61-68. doi:10.1016/0378-1119(89)90359-4.
    • (1989) Gene , vol.77 , pp. 61-68
    • Horton, R.M.1    Hunt, H.D.2    Ho, S.N.3    Pullen, J.K.4    Pease, L.R.5
  • 19
    • 0029018605 scopus 로고
    • Gene therapy for hepatoma cells using a retrovirus vector carrying herpes simplex virus thymidine kinase gene under the control of human alpha-fetoprotein gene promoter
    • Ido, A., Nakata, K., Kato, Y., Nakao, K., Murata, K., Fujita, M., et al. 1995. Gene therapy for hepatoma cells using a retrovirus vector carrying herpes simplex virus thymidine kinase gene under the control of human alpha-fetoprotein gene promoter. Cancer Res. 55: 3105-3109.
    • (1995) Cancer Res , vol.55 , pp. 3105-3109
    • Ido, A.1    Nakata, K.2    Kato, Y.3    Nakao, K.4    Murata, K.5    Fujita, M.6
  • 20
    • 0018889361 scopus 로고
    • Isolation of human T lymphocytes: Comparison between nylon wool filtration and rosetting with neuraminidase and 2-aminoethylisothiouronium bromide (AET)-treated sheep red blood cells (SRBC)
    • doi:10. 1016/0022-1759(80)90164-7
    • Indiveri, F., Huddlestone, J., Pellegrino, M.A., and Ferrone, S. 1980. Isolation of human T lymphocytes: comparison between nylon wool filtration and rosetting with neuraminidase and 2-aminoethylisothiouronium bromide (AET)-treated sheep red blood cells (SRBC). J. Immunol. Methods, 34: 107-115. doi:10. 1016/0022-1759(80)90164-7.
    • (1980) J. Immunol. Methods , vol.34 , pp. 107-115
    • Indiveri, F.1    Huddlestone, J.2    Pellegrino, M.A.3    Ferrone, S.4
  • 21
    • 0029916960 scopus 로고    scopus 로고
    • A single-chain bispecific Fv2 molecule produced in mammalian cells redirects lysis by activated CTL
    • doi:10.1016/0161-5890(95)00087- 9
    • Jost, C.R., Titus, J.A., Kurucz, I., and Segal, D.M. 1996. A single-chain bispecific Fv2 molecule produced in mammalian cells redirects lysis by activated CTL. Mol. Immunol. 33: 211-219. doi:10.1016/0161-5890(95)00087- 9.
    • (1996) Mol. Immunol , vol.33 , pp. 211-219
    • Jost, C.R.1    Titus, J.A.2    Kurucz, I.3    Segal, D.M.4
  • 22
    • 0030772184 scopus 로고    scopus 로고
    • Construction and biological activity of a recombinant bispecific single-chain antibody designed for therapy of minimal residual colorectal cancer
    • doi:10.1007/s002620050431
    • Kufer, P., Mack, M., Gruber, R., Lutterbuse, R., Zettl, F., and Riethmuller, G. 1997. Construction and biological activity of a recombinant bispecific single-chain antibody designed for therapy of minimal residual colorectal cancer. Cancer Immunol. Immunother. 45: 193-197. doi:10.1007/s002620050431.
    • (1997) Cancer Immunol. Immunother , vol.45 , pp. 193-197
    • Kufer, P.1    Mack, M.2    Gruber, R.3    Lutterbuse, R.4    Zettl, F.5    Riethmuller, G.6
  • 23
    • 0034003314 scopus 로고    scopus 로고
    • Activation of lymphocytes by anti-CD3 single-chain antibody dimers expressed on the plasma membrane of tumor cells
    • doi:10.1038/sj.gt.3301080
    • Liao, K.W., Lo, Y.C., and Roffler, S.R. 2000. Activation of lymphocytes by anti-CD3 single-chain antibody dimers expressed on the plasma membrane of tumor cells. Gene Ther. 7: 339-347. doi:10.1038/sj.gt.3301080.
    • (2000) Gene Ther , vol.7 , pp. 339-347
    • Liao, K.W.1    Lo, Y.C.2    Roffler, S.R.3
  • 24
    • 0342632802 scopus 로고    scopus 로고
    • Vaccination with mouse mammary adenocarcinoma cells coexpressing B7-1 (CD80) and B7-2 (CD86) discloses the dominant effect of B7-1 in the induction of antitumor immunity
    • Martin-Fontecha, A., Moro, M., Crosti, M.C., Veglia, F., Casorati, G., and Dellabona, P. 2000. Vaccination with mouse mammary adenocarcinoma cells coexpressing B7-1 (CD80) and B7-2 (CD86) discloses the dominant effect of B7-1 in the induction of antitumor immunity. J. Immunol. 164: 698-704.
    • (2000) J. Immunol , vol.164 , pp. 698-704
    • Martin-Fontecha, A.1    Moro, M.2    Crosti, M.C.3    Veglia, F.4    Casorati, G.5    Dellabona, P.6
  • 25
    • 4444329501 scopus 로고    scopus 로고
    • Cancer vaccine development: On the way to break immune tolerance to malignant cells
    • doi:10.1016/j.yexcr.2004.06. 017
    • Mocellin, S., Rossi, C.R., and Nitti, D. 2004. Cancer vaccine development: on the way to break immune tolerance to malignant cells. Exp. Cell Res. 299: 267-278. doi:10.1016/j.yexcr.2004.06. 017.
    • (2004) Exp. Cell Res , vol.299 , pp. 267-278
    • Mocellin, S.1    Rossi, C.R.2    Nitti, D.3
  • 26
    • 0036889760 scopus 로고    scopus 로고
    • Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway
    • doi:10.1124/pr.54.4.561
    • Qian, Z.M., Li, H., Sun, H., and Ho, K. 2002. Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway. Pharmacol. Rev. 54: 561-587. doi:10.1124/pr.54.4.561.
    • (2002) Pharmacol. Rev , vol.54 , pp. 561-587
    • Qian, Z.M.1    Li, H.2    Sun, H.3    Ho, K.4
  • 27
    • 0033827817 scopus 로고    scopus 로고
    • Antigen-processing machinery breakdown and tumor growth
    • doi:10.1016/S0167-5699(00)01692-3
    • Seliger, B., Maeurer, M.J., and Ferrane, S. 2000. Antigen-processing machinery breakdown and tumor growth. Immunol. Today, 21: 455-464. doi:10.1016/S0167-5699(00)01692-3.
    • (2000) Immunol. Today , vol.21 , pp. 455-464
    • Seliger, B.1    Maeurer, M.J.2    Ferrane, S.3
  • 28
    • 0034256398 scopus 로고    scopus 로고
    • Bacterially produced human B7.1 protein encompassing its complete extracellular domain maintains its costimulatory activity in vitro
    • Shen, W., Wang, Y., Geng, Y., and Si, L. 2000. Bacterially produced human B7.1 protein encompassing its complete extracellular domain maintains its costimulatory activity in vitro. Chin. Med. J. (Engl.), 113: 714-719.
    • (2000) Chin. Med. J. (Engl.) , vol.113 , pp. 714-719
    • Shen, W.1    Wang, Y.2    Geng, Y.3    Si, L.4
  • 29
    • 0242329384 scopus 로고    scopus 로고
    • Vesosky, B., and Hurwitz, A.A. 2003. Modulation of costimulation to enhance tumor immunity. Cancer Immunol. Immunofher. 52: 663-669. doi:10.1007/s00262-003-0424-5.
    • Vesosky, B., and Hurwitz, A.A. 2003. Modulation of costimulation to enhance tumor immunity. Cancer Immunol. Immunofher. 52: 663-669. doi:10.1007/s00262-003-0424-5.
  • 31
    • 1542297653 scopus 로고    scopus 로고
    • Recombinant immunotoxins and retargeted killer cells: Employing engineered antibody fragments for tumor-specific targeting of cytotoxic effectors
    • doi:10.1007/s00262-003-0482-8
    • Weis, W., Biburger, M., Muller, T., Dalken, B., Giesubel, U., Tonn, T., and Uherek, C. 2004. Recombinant immunotoxins and retargeted killer cells: employing engineered antibody fragments for tumor-specific targeting of cytotoxic effectors. Cancer Immunol. Immunother. 53: 217-226. doi:10.1007/s00262-003-0482-8.
    • (2004) Cancer Immunol. Immunother , vol.53 , pp. 217-226
    • Weis, W.1    Biburger, M.2    Muller, T.3    Dalken, B.4    Giesubel, U.5    Tonn, T.6    Uherek, C.7
  • 32
    • 0031839501 scopus 로고    scopus 로고
    • The role of B7-CD28 co-stimulation in tumor rejection
    • doi:10.1093/intimm/10.6. 791
    • Yu, X., Abe, R., and Hodes, R.J. 1998. The role of B7-CD28 co-stimulation in tumor rejection. Int. Immunol. 10: 791-797. doi:10.1093/intimm/10.6. 791.
    • (1998) Int. Immunol , vol.10 , pp. 791-797
    • Yu, X.1    Abe, R.2    Hodes, R.J.3


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