Crystallographic location and mutational analysis of Zn and Cd inhibitory sites and role of lipidic carboxylates in rescuing proton path mutants in cytochrome c oxidase

Biochemistry

Volumn 46, Issue 21, 2007, Pages 6239-6248

  Qin, Ling ^a   Mills, Denise A ^a   Hiser, Carrie ^a   Murphree, Anna ^b   Michael Garavito, R ^a   Ferguson Miller, Shelagh ^a   Hosler, Jonathan ^b  

^a Michigan State University   (United States)

^b UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; CARBOXYLATION; CARBOXYLIC ACIDS; CRYSTALLOGRAPHY; FOURIER ANALYSIS; LIPIDS;

AMPHIPATHIC ACIDS; CRYSTALLOGRAPHIC LOCATION; INHIBITORY SITES; LIPIDIC CARBOXYLATES;

ENZYME INHIBITION;

AMINO ACID; ARACHIDONIC ACID; CADMIUM; CARBOXYLIC ACID; CYTOCHROME C OXIDASE; LIPID; PROTON; ZINC;

ARTICLE; BINDING SITE; CRYSTALLOGRAPHY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBUNIT; METAL BINDING; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; RHODOBACTER SPHAEROIDES;

BINDING SITES; CADMIUM; CRYSTALLOGRAPHY, X-RAY; ELECTRON TRANSPORT COMPLEX IV; FATTY ACIDS; MUTATION; PROTONS; RHODOBACTER SPHAEROIDES; ZINC;

RHODOBACTER SPHAEROIDES;

EID: 34249668338     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi700173w     Document Type: Article

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