Analysis of the rainbow trout solute carrier 11 family reveals iron import ≤ pH 7.4 and a functional isoform lacking transmembrane domains 11 and 12

FEBS Letters

Volumn 581, Issue 14, 2007, Pages 2599-2604

  Cooper, C A ^a   Shayeghi, M ^a   Techau, M E ^b   Capdevila, D M ^c   MacKenzie, S ^c   Durrant, C ^a   Bury, N R ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Divalent metal transporter 1 (DMT1); Fish; Iron; Natural resistance associated macrophage protein (Nramp); Rainbow trout; Transmembrane domains

Indexed keywords

CARRIER PROTEIN; IRON; ISOPROTEIN; METAL; SOLUTE CARRIER 11; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CODON; CONTROLLED STUDY; EXON; GILL; IRON TRANSPORT; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN ISOLATION; RAINBOW TROUT;

ANIMALS; BIOLOGICAL TRANSPORT; CATION TRANSPORT PROTEINS; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HYDROGEN-ION CONCENTRATION; IRON; METALS; MOLECULAR SEQUENCE DATA; ONCORHYNCHUS MYKISS; OOCYTES; PROTEIN ISOFORMS; SEQUENCE ANALYSIS, DNA; XENOPUS;

ONCORHYNCHUS MYKISS; SALMONIDAE; VERTEBRATA;

EID: 34249665580     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.04.081     Document Type: Article

References (42)

1. Vidal S.M., Malo D., Vogan K., Skamene E., and Gros P. Natural resistance to infection with intracellular parasites: Isolation of a candidate for Bcg. Cell 73 3 (1993) 469-485
2. Cellier M., Prive G., Belouchi A., Kwan T., Rodrigues V., Chia W., and Gros P. Nramp defines a family of membrane proteins. Proc. Natl. Acad. Sci. USA 92 22 (1995) 10089-10093
3. Gunshin H., Mackenzie B., Berger U.V., Gunshin Y., Romero M.F., Boron W.F., Nussberger S., Gollan J.L., and Hediger M.A. Cloning and characterisation of a mammalian proton coupled metal ion transporter. Nature 388 (1997) 842-888
4. +/bivalent cation transporter. Biochem. J. 354 (2001) 511-519
5. +-coupled metal-ion transporters NRAMP1 and DMT1. Pflugers Arch. 447 5 (2004) 571-579
6. Forbes J.R., and Gros P. Iron, manganese, and cobalt transport by Nramp1 (SLC11a1) and Nramp2 (SLC11a2) expressed at the plasma membrane. Blood 102 5 (2003) 1884-1892
7. Gruenheid S., Canonne-Hergaux F., Gauthier S., Hackam D.J., Grinstein S., and Gros P. The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes. J. Exp. Med. 189 5 (1999) 831-841
8. Jabado N., Canonne-Hergaux F., Gruenheid S., Picard V., and Gros P. Iron transporter Nramp2/DMT-1 is associated with the membrane of phagosomes in macrophages and Sertoli cells. Blood 100 7 (2002) 2617-2622
9. Sacher A., Cohen A., and Nelson N. Properties of the mammalian and yeast metal-ion transporters DCT1 and Smf1p expressed in Xenopus laevis oocytes. J. Exp. Biol. 204 6 (2001) 1053-1061
10. Bannon D.I., Abounader R., Lees P.S.J., and Bressler J.P. Effect of DMT1 knockdown on iron, cadmium and lead uptake in Caco-2 cells. Am. J. Physiol. 284 (2003) C44-C50
11. Arredondo M., Munoz P., Mura C.V., and Nunnez M.T. DMT1, a physiologically relevant apical Cu transporter of intestinal cells. Am. J. Physiol. 284 (2003) C1525-C1530
12. Dorschner M.O., and Phillips R.B. Comparative analysis of two Nramp loci from rainbow trout. DNA Cell Biol. 18 7 (1999) 573-583
13. Saeij J.P.J., Wiegertjes G.F., and Stet R.J.M. Identification and characterisation of a fish natural resistance associate macrophage protein (Nramp) cDNA. Immunogenetics 50 (1999) 50-60
14. Chen H., Waldbieser G.C., Rice C.D., Elibol B., Wolters W.R., and Hanson L.A. Isolation and characterisation of channel catfish natural resistance associated macrophage protein gene. Dev. Comp. Immunol. 26 (2002) 517-531
15. Donovan A., Brownlie A., Dorschner M.O., Zhou Y., Pratt S.J., Paw B.H., Phillips R.B., Thisse C., Thisse B., and Zon L.I. The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1). Blood 100 13 (2002) 4655-4659
16. Sibthorpe D., Baker A.M., Gilmartin B.J., Blackwell J.M., and White J.K. Comparative analysis of two SLC11 (NRAMP) loci in Takifugu rubripes. DNA Cell Biol. 23 1 (2004) 45-58
17. Chen S.L., Xu M.Y., Ji X.S., and Yu G.C. Cloning and characterisation of natural resistance associated macrophage protein (Nramp) cDNA from red sea bream (Pagrus major). Fish Shellfish Immunol. 17 4 (2004) 305-313
18. Burge E.J., Gauthier D.T., Ottinger C.A., and Van Veld P.A. Mycobacterium - Inducibale NRAMP in Striped Bass (Morone saxatilis). Infect. Immun. 72 3 (2004) 1626-1636
19. Chen Y.J., Lin C.H., Ou T.T., Wu C.C., Tsai W.C., Liu H.W., and Yen J.H. Solute carrier family 11 member A1 gene polymorphisms in reactive arthritis. J. Clin. Immunol. 27 (2007) 46-52
20. Iolascon A., d'Apolito M., Servedio V., Cimmino F., Piga A., and Camaschella C. Microcytic anaemia and hepatic iron overload in a child with compound heterozygous mutations in DMT1 (SCL11A2). Blood 107 1 (2006) 349-354
21. Touret N., Martin-Orozco N., Paroutis P., Furuya W., Lam-Yuk-Tseung S., Forbes J., Gros P., and Grinstein S. Molecular and cellular mechanisms underlying iron transport deficiency in microcytic anaemia. Blood 104 5 (2004) 1526-1533
22. Lam-Yuk-Tseung S., Camaschella C., Iolascon A., and Gros P. A novel R416C mutation in human DMT1 (SLC11A2) displays pleiotropic effects on function and causes microcytic anaemia and hepatic iron overload. Blood Cells Mol. Dis. 36 (2006) 347-354
23. 2-induced cytotoxicity. Toxicol. Appl. Pharmacol. 205 (2005) 225-236
24. Mckie A.T., Marciani P., Rolfs A., Brennan K., Wehr K., Barrow D., Miret S., Bomford A., Peters T.J., Farzaneh F., Hediger M.A., hentze M.W., and Simpson R.J. A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Mol. Cell 5 (2000) 299-309
25. Sandell E.D. Colourmetric Determination of Trace metals. 3rd ed. (1959), Inter Science publishers, New York and London
26. Kishi F., and Tabuchi M. Human natural resistance-associated macrophage protein 2: gene cloning and protein identification. Biochem. Biophys. Res. Commun. 251 (1998) 775-783
27. Allendorf F., and Thorgaard G.H. Tetraploidy and the evolution of salmonid fishes. In: Turner B.J. (Ed). Evolutionary genetics of fishes (1984), Plenum Press, New York 1-53
28. Lam-Yuk-Tseung S., Govoni G., Forbes J., and Gros P. Iron transport by Nramp2/DMT1: pH regulation of transport by 2 histidines in transmembrane domain 6. Blood 101 (2003) 3699-3707
29. Cooper, C.A. and Bury, N.R. (2007). The gills as an important uptake route for the essential nutrient iron in freshwater rainbow trout Oncorhynchus mykiss. J. Fish Biol., doi:10.1111/j.1095-8649.2007.01474.
30. - channel regulated by intracellular pH. J. Biol. Chem. 280 8 (2005) 6463-6470
31. 2+ transport and uncoupled fluxes. Pflugers Arch. 451 (2006) 544-558
32. Roeder M., and Roeder R.H. Effect of iron on the growth rate of fishes. J. Nutr. 90 (1966) 86-90
33. Bury N.R., Grosell M., Wood C.M., Hogstrand C., Wilson R.W., Rankin J.C., Busk M., Lecklin T., and Jensen F.B. Intestinal iron uptake in the European flounder (Platichthys flesus). J. Exp. Biol. 204 (2001) 3779-3787
34. Bury N., and Grosell M. Iron acquisition by teleost fish. Comp. Biochem. Physiol. 135C (2003) 97-105
35. Bury N., and Grosell M. Waterborne iron acquisition by a freshwater teleost fish, zebrafish Danio rerio. J. Exp. Biol. (2003) 206
36. Cooper C.A., Handy R.D., and Bury N.R. The effects of dietary iron on intestinal and branchial assimilation of both essential and toxic metals in vivo via iron transporters in a freshwater teleost fish species, zebrafish (Danio rerio). Aquat. Toxicol. 79 (2006) 167-175
37. Cooper C.A., Bury N.R., and Grosell M. The effects of pH and the iron redox state on iron uptake in the intestine of a marine teleost fish, gulf toadfish (Opsanus beta). Comp. Biochem. Physiol. 143A (2006) 292-298
38. Scott D.M., Lucas M.C., and Wilson R.W. The effect of high pH on ion balance,nitrogen metabolism and behaviour in freshwater fish from a eutrophic lake: a laboratory and field study. Aquat. Toxicol. 73 (2005) 31-43
39. Vielma J., and Lall S.P. Dietary formic acid enhances apparent digestibility of minerals in rainbow trout, Oncorhynchus mykiss (Walbaum). Aqua. Nutr. 3 (1997) 265-268
40. Wilson R.W., and Grosell M. Intestinal bicarbonate secretion in marine teleost fish-source of bicarbonate, pH sensitivity, and consequences for whole animal acid-base and calcium homeostasis. Biochim. Biophys. Acta 1618 (2003) 163-174
41. Bressler J.P., Olivi L., Cheong J.H., Kim Y., and Bannon D. Divalent metal transporter 1 in lead and cadmium transport. Ann. NY Acad. Sci. 1012 (2004) 142-152
42. 2+ transporter. FEBS Lett. 579 12 (2005) 2727-2730