Development and validation of a high-performance liquid chromatographic method using fluorescence detection for the determination of vardenafil in small volumes of rat plasma and bile

Journal of Chromatography A

Volumn 1154, Issue 1-2, 2007, Pages 222-229

  Cheng, Ching Ling ^a   Kang, Guei Jen ^b   Chou, Chen Hsi ^b  

^a CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Erectile dysfunction; Fluorescence detection; HPLC; Pharmacokinetics; Vardenafil

Indexed keywords

ACETONITRILE; FLOW RATE; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHARMACOKINETICS; RATS;

BILE; BILIARY EXCRETION; ERECTILE DYSFUNCTION; FLUORESCENCE DETECTION; VARDENAFIL;

BODY FLUIDS;

ACETONITRILE; AMMONIUM ACETATE; CISAPRIDE; VARDENAFIL;

ACCURACY; AQUEOUS SOLUTION; ARTICLE; BILIARY EXCRETION; CALIBRATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BILE LEVEL; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG EXCRETION; DRUG STRUCTURE; EXCITATION; FLOW RATE; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PH; PRIORITY JOURNAL; RAT; SEPARATION TECHNIQUE; STANDARD; VALIDATION STUDY;

ANIMALS; BILE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; IMIDAZOLES; MALE; PIPERAZINES; SPECTROMETRY, FLUORESCENCE; SULFONES; TRIAZINES;

RATTUS;

EID: 34249658481     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2007.03.077     Document Type: Article

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