Knocking down p53 with siRNA does not affect the overexpression of p21 WAF-1 after exposure of IMR-90 hTERT fibroblasts to a sublethal concentration of H2O2 leading to premature senescence

Annals of the New York Academy of Sciences

Volumn 1100, Issue , 2007, Pages 316-322

  Zdanov, Stephanie ^a   Debacq Chainiaux, Florence ^a   Toussaint, Olivier ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

Author keywords

Fibroblasts; Hydrogen peroxide; Oxidative stress; p53; Senescence; Telomerase

Indexed keywords

BETA GALACTOSIDASE; CYCLIN DEPENDENT KINASE INHIBITOR 1; DNA; HYDROGEN PEROXIDE; MESSENGER RNA; PROTEIN P53; SMALL INTERFERING RNA; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; TELOMERASE; TERT PROTEIN, HUMAN; UNCLASSIFIED DRUG;

CELL CYCLE ARREST; CELL SHAPE; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVITY; FETUS; FIBROBLAST; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; SENESCENCE; STRESS; ARTICLE; CELL AGING; CELL LINE; GENE EXPRESSION REGULATION; GENE SILENCING; METABOLISM; OXIDATIVE STRESS; TUMOR SUPPRESSOR GENE;

CELL AGING; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FIBROBLASTS; GENE EXPRESSION REGULATION; GENE SILENCING; GENES, P53; HUMANS; HYDROGEN PEROXIDE; OXIDATIVE STRESS; RNA, MESSENGER; RNA, SMALL INTERFERING; TELOMERASE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34249656140     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1395.034     Document Type: Conference Paper

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