Galectin-3 expression is correlated with abnormal prion protein accumulation in murine scrapie

Neuroscience Letters

Volumn 420, Issue 2, 2007, Pages 138-143

  Jin, Jae Kwang ^a   Na, Yeo Jung ^a   Song, Joon Ho ^a   Joo, Hong Gu ^b   Kim, Seungjoon ^b   Kim, Jae Il ^c   Choi, Eun Kyoung ^a   Carp, Richard I ^c   Kim, Yong Sun ^a   Shin, Taekyun ^b  

^a Hallym University Medical Center   (South Korea)

^b Jeju National University   (South Korea)

^c NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Galectin 3; Macrophage; Microglia; Prion disease; Scrapie

Indexed keywords

GALECTIN 3; MESSENGER RNA; PRION PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; CORRELATION ANALYSIS; EXPERIMENTAL MODEL; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MICROGLIA; MOUSE; NERVE DEGENERATION; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCRAPIE; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL MARKERS; BRAIN; GALECTIN 3; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOSIS; MACROPHAGES; MICE; MICE, INBRED C57BL; MICROGLIA; NERVE DEGENERATION; NEURONS; PLANT LECTINS; PRPSC PROTEINS; RNA, MESSENGER; SCRAPIE; UP-REGULATION;

EID: 34249324522     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.04.069     Document Type: Article

References (23)

1. Almkvist J., and Karlsson A. Galectins as inflammatory mediators. Glycoconj. J. 19 (2004) 575-581
2. Giese A., Brown D.R., Groschup M.H., Feldmann C., Haist I., and Kretzschmar H.A. Role of microglia in neuronal cell death in prion disease. Brain Pathol. 8 (1998) 449-457
3. Hughes R.C. Secretion of the galectin family of mammalian carbohydrate-binding proteins. Biochim. Biophys. Acta 1473 (1999) 172-185
4. Inohara H., and Raz A. Identification of human melanoma cellular and secreted ligands for galectin-3. Biochem. Biophys. Res. Commun. 201 (1994) 1366-1375
5. Jin J.K., Na Y.J., Moon C., Kim H., Ahn M., Kim Y.S., and Shin T. Increased expression of osteopontin in the brain with scrapie infection. Brain Res. 1072 (2006) 227-233
6. Kim J.I., Wang C., Kuizon S., Xu J., Barengolts D., Gray P.C., and Rubenstein R. Simple and specific detection of abnormal prion protein by a magnetic bead-based immunoassay coupled with laser-induced fluorescence spectrofluorometry. J. Neuroimmunol. 158 (2005) 112-119
7. Kuwabara I., and Liu F.T. Galectin-3 promotes adhesion of human neutrophils to laminin. J. Immunol. 156 (1996) 3939-3944
8. Le Y., Yazawa H., Gong W., Yu Z., Ferrans V.J., Murphy P.M., and Wang J.M. The neurotoxic prion peptide fragment PrP106-126 is a chemotactic agonist for the G protein-coupled receptor formyl peptide receptor-like 1. J. Immunol. 166 (2001) 1448-1451
9. Lee H.P., Jun Y.C., Choi J.K., Kim J.I., Carp R.I., and Kim Y.S. The expression of RANTES and chemokine receptors in the brains of scrapie-infected mice. J. Neuroimmunol. 158 (2005) 26-33
10. Liu F.T., Patterson R.J., and Wang J.L. Intracellular functions of galectins. Biochim. Biophys. Acta 1572 (2002) 263-273
11. Mok S.W., Thelen K.M., Riemer C., Bamme T., Gultner S., Lutjohann D., and Baier M. Simvastatin prolongs survival times in prion infections of the central nervous system. Biochem. Biophys. Res. Commun. 348 (2006) 697-702
12. Nangia-Makker P., Honjo Y., Sarvis R., Akahani S., Hogan V., Pienta K.J., and Raz A. Galectin-3 induces endothelial cell morphogenesis and angiogenesis. Am. J. Pathol. 156 (2000) 899-909
13. Prusiner S.B. Molecular biology of prion diseases. Science 252 (1991) 1515-1522
14. Reichert F., and Rotshenker S. Galectin-3/MAC-2 in experimental allergic encephalomyelitis. Exp. Neurol. 160 (1999) 508-514
15. Riemer C., Neidhold S., Burwinkel M., Schwarz A., Schultz J., Kratzshmar J., Monning U., and Baier M. Gene expression profiling of scrapie-infected brain tissue. Biochem. Biophys. Res. Commun. 323 (2004) 556-564
16. Rubinstein N., Ilarregui J.M., Toscano M.A., and Rabinovich G.A. The role of galectins in the initiation, amplification and resolution of the inflammatory response. Tissue Antigens 64 (2004) 1-12
17. Sano H., Hsu D.K., Apgar J.R., Yu L., Sharma B.B., Kuwabara I., Izui S., and Liu F.T. Critical role of galectin-3 in phagocytosis by macrophages. J. Clin. Invest. 112 (2003) 389-397
18. Sano H., Hsu D.K., Yu L., Apgar J.R., Kuwabara I., Izui S., and Liu F.T. Human galectin-3 is a novel chemoattractant for monocytes and macrophages. J. Immunol. 165 (2003) 2156-2164
19. Silei V., Fabrizi C., Venturini G., Salmona M., Bugiani O., Tagliavini F., and Lauro G.M. Activation of microglial cells by PrP and β-amyloid fragments raises intracellular calcium through L-type voltage-sensitive calcium channels. Brain Res. 818 (1999) 168-170
20. Walther M., Kuklinski S., Pesheva P., Guntinas-Lichius O., Angelov D.N., Neiss W.F., Asou H.A., and Probstmeier R. Galectin-3 is upregulated in microglial cells in response to ischemic brain lesions, but not to facial nerve axotomy. J. Neurosci. Res. 61 (2000) 430-435
21. Warfield P.R., Makker P.N., Raz A., and Ochieng J. Adhesion of human breast carcinoma to extracellular matrix proteins is modulated by galectin-3. Invasion Metastasis 17 (1997) 101-112
22. Williams A.E., Van Dam A.M., Man-A-Hing W.K.H., Berkenbosch F., Eikelenboom P., and Fraser H. Cytokines, prostaglandins and lipocortin-1 are present in the brains of scrapie-infected mice. Brain Res. 654 (1994) 200-206
23. Williams A.E., Van Dam A.M., Ritchie D., Eikelenboom P., and Fraser H. Immunocytochemical appearance of cytokines, prostaglandin E2 and lipocortin-1 in the CNS during the incubation period of murine scrapie correlates with progressive PrP accumulations. Brain Res. 754 (1997) 171-180