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Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes
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Liraglutide significantly improves glycemic control, and lowers body weight without risk of either major or minor hypoglycemic episodes in subjects with type 2 diabetes
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June 9-13, Washington, DC. Abstract 115-OR.
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Vilsboll T., Zdravkovic M., Le-Thi T., et al. Liraglutide significantly improves glycemic control, and lowers body weight without risk of either major or minor hypoglycemic episodes in subjects with type 2 diabetes. In: Program and Abstracts of the 66th Annual Meeting of the American Diabetes Association; June 9-13, 2006 ; Washington, DC. Abstract 115-OR.
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Liraglutide treatment, blood pressure and biomarkers of cardiovascular risk in patients with type 2 diabetes: 14 weeks monotherapy study
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Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: Results from two randomized, double-blind, placebo-controlled studies with single oral doses
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Herman GA, Stevens C., Van Dyck K., et al. Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: results from two randomized, double-blind, placebo-controlled studies with single oral doses. Clin Pharmacol Ther. 2005 ; 78: 675-688.
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Pharmacokinetic and pharmacodynamic properties of multiple oral doses of sitagliptin, a dipeptidyl peptidase-IV inhibitor: A double-blind, randomized, placebo-controlled study in healthy male volunteers
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Bergman AJ, Stevens C., Zhou Y., et al. Pharmacokinetic and pharmacodynamic properties of multiple oral doses of sitagliptin, a dipeptidyl peptidase-IV inhibitor: a double-blind, randomized, placebo-controlled study in healthy male volunteers. Clin Ther. 2006 ; 28: 55-72.
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Sitagliptin monotherapy improved glycemic control in the fasting and postprandial states and beta cell function after 24 weeks in patients with type 2 diabetes (T2DM)
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Aschner P., Kipnes M., Lunceford J., Mickel C., Davies M., Williams-Herman D. Sitagliptin monotherapy improved glycemic control in the fasting and postprandial states and beta cell function after 24 weeks in patients with type 2 diabetes (T2DM). In: Program and Abstracts of the 66th Annual Meeting of the American Diabetes Association ; June 9-13, 2006 ; Washington, DC. Abstract 1995 -PO.
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Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels in type 2 diabetes
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Ahrn B., Landin-Olsson M., Jansson PA, Svensson M., Holmes D., Schweizer A. Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels in type 2 diabetes. J Clin Endocrinol Metab. 2004 ; 89: 2078-2084.
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Sitagliptin added to ongoing metformin therapy enhanced glycemic control and beta-cell function in patients with type 2 diabetes
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Program and Abstracts of the 66th Annual Meeting of the American Diabetes Association
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33749392658
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The DPP-4 inhibitor vildagliptin increases pancreatic beta cell neogenesis and decreases apoptosis
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Duttaroy A., Voelker F., Merriam K., Zhang X., Ren X., Burkey B. The DPP-4 inhibitor vildagliptin increases pancreatic beta cell neogenesis and decreases apoptosis. In: Program and Abstracts of the 65th Scientific Sessions of the American Diabetes Association ; June 10-14, 2005 ; San Diego, Calif. Abstract 572-P.
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Duttaroy, A.1
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