Squalene-derived flexible linkers for bioactive peptides

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 12, 2007, Pages 3310-3313

  Jagadish, Bhumasamudram ^a   Sankaranarayanan, Rajesh ^a   Xu, Liping ^b   Richards, Reyniak ^a   Vagner, Josef ^a   Hruby, Victor J ^a,b   Gillies, Robert J ^b   Mash, Eugene A ^a  

^a University of Arizona   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

Click chemistry; Ligands; Melanocyte stimulating hormone; Multimeric; NDP MSH

Indexed keywords

ALPHA INTERMEDIN DERIVATIVE; AZIDE; COPPER; INTERMEDIN; MELANOCORTIN 4 RECEPTOR; N HYDROXYSUCCINIMIDOYL 5 HEXYNOATE; PEPTIDE DERIVATIVE; SQUALENE; SUCCINIMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CATALYSIS; CATALYST; CYCLIZATION; LIPOGENESIS; PROTEIN LIPID INTERACTION; RECEPTOR AFFINITY; STEREOCHEMISTRY;

ALKYNES; ALPHA-MSH; AMINO ACID SEQUENCE; AZIDES; BINDING SITES; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COPPER; CYCLIZATION; DIMERIZATION; HUMANS; LIGANDS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PEPTIDES; RECEPTOR, MELANOCORTIN, TYPE 4; SQUALENE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SUCCINIMIDES;

EID: 34249307488     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.04.001     Document Type: Article

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