Impact of preservation solution on the extent of blood-air barrier damage and edema formation in experimental lung transplantation

Anatomical Record

Volumn 290, Issue 5, 2007, Pages 491-500

  Mühlfeld, Christian ^a   Müller, Katharina ^b   Pallesen, Lars Peder ^b   Sandhaus, Tim ^c   Madershahian, Navis ^d   Richter, Joachim ^b   Wahlers, Thorsten ^d   Wittwer, Thorsten ^d   Ochs, Matthias ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

Author keywords

Electron microscopy; Ischemia; Lung transplantation; Reperfusion; Stereology

Indexed keywords

CELSIOR; PERFADEX; PRESERVATION SOLUTION; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ISCHEMIA; LUNG EDEMA; LUNG GAS EXCHANGE; LUNG TRANSPLANTATION; NONHUMAN; ORGAN DONOR; ORGAN PRESERVATION; PRIORITY JOURNAL; RECIPIENT; REPERFUSION INJURY; STEREOMETRY; SWINE;

ANIMALS; BLOOD-AIR BARRIER; CITRATES; DISACCHARIDES; ELECTROLYTES; GLUTAMATES; GLUTATHIONE; HISTIDINE; LUNG; LUNG TRANSPLANTATION; MANNITOL; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, ANIMAL; ORGAN PRESERVATION; ORGAN PRESERVATION SOLUTIONS; PULMONARY EDEMA; RANDOM ALLOCATION; REPERFUSION INJURY; SWINE;

SUIDAE;

EID: 34249295544     PISSN: None     EISSN: 19328494     Source Type: Journal    
DOI: 10.1002/ar.20518     Document Type: Article

References (42)

1. Albertine KH. 1998. Histopathology of pulmonary edema and the acute respiratory distress syndrome. In: Matthay MA, Ingbar DH, editors. Pulmonary edema. New York: Marcel Dekker. p 37-83.
2. Arcasoy SM, Kotloff RM. 1999. Lung transplantation. N Engl J Med 340:1081-1091.
3. Bachofen H, Weibel ER. 1998. Structure-function relationships in the pathogenesis of pulmonary edema. In: Weir EK, Reeves JT, editors. Pumonary edema. Armonk, NY: Futura. p 17-33.
4. Christie JD, Kotloff RM, Ahya VN, Tino G, Pochettino A, Gaughan C, DeMissie E, Kimmel SE. 2005a. The effect of primary graft dysfunction on survival after lung transplantation. Am J Respir Crit Care Med 171:1312-1316.
5. Christie JD, Carby M, Bag R, Corris P, Hertz M, Weill D. 2005b. Report of the ISHLT working group on primary lung graft dysfunction: II, definition, a consensus statement of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant 24:1454-1459.
6. Daud SA, Yusen RD, Meyers BF, Chakinala MM, Walter MJ, Aloush AA, Patterson GA, Trulock EP, Hachem RR. 2007. Impact of immediate primary lung allograft dysfunction on bronchiolitis obliterans syndrome. Am J Respir Crit Care Med 175:507-513.
7. De Perrot M, Liu M, Keshavjee S. 2003. Ischemia-reperfusion-induced lung injury. Am J Respir Crit Care Med 167:490-511.
8. De Perrot M, Bonser RS, Dark J, Kelly RF, McGiffin D, Menza R, Pajaro O, Schueler S, Verleden GM. 2005. Report of the ISHLT working group on primary lung graft dysfunction: III, donor-related risk factors and markers. J Heart Lung Transplant 24:1460-1467.
9. D'Ovidio F, Keshavjee S. 2006. Lung preservation techniques. In: Lynch JP III, Ross DJ, editors. Lung and heart-lung transplantation. New York: Taylor and Francis. p 325-347.
10. Fehrenbach H, Schepelmann D, Albes JM, Bando T, Fischer F, Fehrenbach A, Stolte N, Wahlers T, Richter J. 1999. Pulmonary ischemia/reperfusion injury: a quantitative study of structure and function in isolated heart-lungs of the rat. Anat Rec 255:84-99.
11. Fehrenbach A, Fehrenbach H, Wittwer T, Ochs M, Wahlers T, Richter J. 2001. Evaluation of pulmonary edema: stereological versus gravimetrical analysis. Eur Surg Res 33:270-278.
12. Fehrenbach A, Pufe T, Wittwer T, Nagib R, Dreyer N, Pech T, Petersen W, Fehrenbach H, Wahlers T, Richter J. 2003. Reduced vascular endothelial growth factor correlates with alveolar epithelial damage after experimental ischemia and reperfusion. J Heart Lung Transplant 22:967-978.
13. Fiser SM, Tribble CG, Long SM, Kaza AK, Kern JA, Jones DR, Robbins MK, Kron IL. 2002. Ischemia-reperfusion injury after lung transplantation increases risk of late bronchiolitis obliterans syndrome. Ann Thorac Surg 73:1041-1048.
14. Heffner JE. 1998. Mechanisms underlying ischemia/reperfusion injury of the lung. In: Matthay MA, Ingbar DH, editors. Pulmonary edema. New York: Marcel Dekker. p 379-412.
15. Howell DN, Palmer SM. 2006. Pathology of the lung transplant. In: Lynch JP III, Ross DJ, editors. Lung and heart-lung transplantation. New York: Taylor and Francis. p 683-722.
16. Keshavjee SH, Yamazaki F, Yokomise H, Cardoso PF, Mullen JB, Slutsky AS, Patterson GA. 1992. The role of dextran 40 and potassium in extended hypothermic lung preservation for transplantation. J Thorac Cardiovasc Surg 103:314-325.
17. Kinnula VL, Crapo JD, Raivo KO. 1995. Generation and disposal of reactive oxygen metabolites in the lung. Lab Invest 73:3-19.
18. Maina JN, West JB. 2004. Thin and strong! the bioengineering dilemma in the structural and functional design of the blood-gas barrier. Physiol Rev 85:811-844.
19. Martin TR. 2002. Neutrophils and lung injury: getting it right. J Clin Invest 110:1603-1605.
20. Montaner JSG, Tsang J, Evans KG, Mullen JBM, Burns AR, Walker DC, Wiggs B, Hogg JC. 1986. Alveolar epithelial damage: a critical difference between high pressure and oleic acid-indiced low pressure pulmonary edema. J Clin Invest 77:1786-1796.
21. Mulligan MS. 2006. Primary graft dysfunction following lung transplantation: pathogenesis and impact on early and late outcomes. In: Lynch JP III, Ross DJ, editors. Lung and heart-lung transplantation. New York: Taylor and Francis. p 437-464.
22. Ng CSH, Wan S, Arifi A, Yim APC. 2006. Inflammatory response to pulmonary ischemia-reperfusion injury. Surg Today 36:205-214.
23. Novick RJ, Gehman KE, Ali IS, Lee J. 1996. Lung preservation: the importance of endothelial and alveolar type II cell integrity. Ann Thorac Surg 62:302-314.
24. Ochs M, Nenadic I, Fehrenbach A, Albes JM, Wahlers T, Richter J, Fehrenbach H. 1999. Ultrastructural alterations in intraalveolar surfactant subtypes after experimental ischemia and reperfusion. Am J Respir Crit Care Med 160:718-724.
25. Ochs M, Fehrenbach H, Nenadic I, Bando T, Fehrenbach A, Schepelmann D, Albes JM, Wahlers T, Richter J. 2000. Preservation of intraalveolar surfactant in a rat lung ischaemia/reperfusion injury model. Eur Respir J 15:526-531.
26. Ochs M. 2006. A brief update on lung stereology. J Microsc 222:188-200.
27. Sakamaki F, Hoffmann H, Müller C, Dienemann H, Messmer K, Schildberg FW. 1997. Reduced lipid peroxidation and ischemia-reperfusion injury after lung transplantation using low-potassium dextran solution for lung preservation. Am J Respir Crit Care Med 156:1073-1081.
28. Scherle W. 1970. A simple method for volumetry of organs in quantitative stereology. Mikroskopie 26:57-60.
29. Soccal PM, Gasche Y, Pache JC, Schneuwly O, Slosman DO, Morel DR, Spiliopoulos A, Suter PM, Nicod LP. 2000. Matrix metalloproteinases correlate with alveolar-capillary permeability alteration in lung ischemia-reperfusion injury. Transplantation 70:998-1005.
30. Staub NC. 1974. Pulmonary edema. Physiol Rev 54:678-811.
31. Steen S. 2001. Preservation of the endothelium in cardiovascular surgery: some practical suggestions, a review. Scand Cardiovasc J 35:297-301.
32. Trulock EP. 1997. Lung transplantation. Am J Respir Crit Care Med 155:789-818.
33. Van Raemdonck D, Steen S. 2003. Lung preservation. Eur Respir Mon 26:86-97.
34. Van Raemdonck D, Strüber M, Venuta F, Vlasselaers D, Wisser W, Erasmus ME. 2004. Strategies in the prevention and the treatment of ischaemia-reperfusion injury after lung transplantation. Eur Respir Mon 29:66-88.
35. Velazquez M, Weibel ER, Kuhn C III, Schuster DP. 1991. PET evaluation of pulmonary vascular permeability: a structure-function correlation. J Appl Physiol 70:2206-2216.
36. Weibel ER. 1979. Practical methods for biological morphometry. London: Academic Press.
37. Weibel ER. 1984. The pathway for oxygen. Cambridge, MA: Harvard University Press.
38. Weibel ER, Hsia CCW, Ochs M. 2007. How much is there really? why stereology is essential in lung morphometry. J Appl Physiol 102:459-467.
39. Wierup P, Liao Q, Bolys R, Sjoberg T, Rippe B, Steen S. 2005. Lung edema formation during cold perfusion: important differences between rat and porcine lung. J Heart Lung Transplant 24:379-385.
40. Wilkes DS, Egan TM, Reynolds HY. 2005. Lung transplantation: opportunities for research and clinical advancement. Am J Respir Crit Care Med 172:944-955.
41. Wittwer T, Franke U, Fehrenbach A, Meyer D, Sandhaus T, Pfeifer F, Dreyer N, Mueller T, Schubert H, Richter J, Wahlers T. 2004. Impact of retrograde graft preservation in perfadex-based experimental lung transplantation. J Surg Res 117:239-248.
42. Wittwer T, Franke UFW, Fehrenbach A, Ochs M, Sandhaus T, Schuette A, Richter S, Dreyer N, Knudsen L, Müller T, Schubert H, Richter J, Wahlers T. 2005. Experimental lung transplantation: impact of preservation solution and route of delivery. J Heart Lung Transplant 24:1081-1090.