One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones using chloroacetic acid as catalyst

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 12, 2007, Pages 3508-3510

  Yu, Yang ^a   Liu, Di ^a   Liu, Chunsheng ^a   Luo, Genxiang ^a  

^a LIAONING SHIHUA UNIVERSITY   (China)

Author keywords

Biginelli reaction; Chloroacetic acid; Dihydropyrimidinones; One pot; Solvent free; Synthesis

Indexed keywords

1,3 DICARBONYL DERIVATIVE; 3,4 DIHYDROPYRIMIDIN 2(1H) ONE DERIVATIVE; 5 ETHOXYCARBONYL 6 METHYL 4 PHENYL 3,4 DIHYDROPYRIMIDIN 2(1H) ONE; ACETIC ACID; ALDEHYDE; CARBONYL DERIVATIVE; CHLOROACETIC ACID; PHOSPHOMOLYBDIC ACID; PHOSPHOTUNGSTIC ACID; POTASSIUM ACID SULFATE; PYRIMIDINE DERIVATIVE; TOLUENESULFONIC ACID; TOLUENESULFONIC ACID DERIVATIVE; TRIFLUOROACETIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BIGINELLI REACTION; CATALYST; DRUG EFFICACY; DRUG SYNTHESIS; ONE POT SYNTHESIS; PRODUCT RECOVERY; REACTION ANALYSIS; REACTION TIME; SOLVENT EFFECT;

ACETIC ACIDS; ALDEHYDES; CALCIUM CHANNEL BLOCKERS; CATALYSIS; MODELS, CHEMICAL; THIOUREA; UREA;

EID: 34249284144     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.12.068     Document Type: Article

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