Effect of multivitamin and multimineral supplementation on cognitive function in men and women aged 65 years and over: A randomised controlled trial

Nutrition Journal

Volumn 6, Issue , 2007, Pages

  McNeill, Geraldine ^a   Avenell, Alison ^b   Campbell, Marion K ^b   Cook, Jonathan A ^b   Hannaford, Philip C ^a   Kilonzo, Mary M ^a   Milne, Anne C ^b   Ramsay, Craig R ^b   Seymour, D Gwyn ^a   Stephen, Audrey I ^b   Vale, Luke D ^a,b  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; COPPER; CYANOCOBALAMIN; FOLIC ACID; IODINE; IRON; MANGANESE; MINERAL; MULTIVITAMIN; NICOTINIC ACID; PANTOTHENIC ACID; PYRIDOXINE; RETINOL; RIBOFLAVIN; THIAMINE; VITAMIN D; ZINC; VITAMIN;

AGED; ARTICLE; CLINICAL TRIAL; COGNITION; COGNITIVE DEFECT; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEMORY; NUTRITIONAL DEFICIENCY; QUESTIONNAIRE; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SPEECH; SUPPLEMENTATION; UNITED KINGDOM; AGING; DIET SUPPLEMENTATION; DRUG EFFECT; METHODOLOGY; MULTICENTER STUDY; NUTRITION; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; PSYCHOMETRY;

AGED; AGING; COGNITION; COGNITION DISORDERS; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MINERALS; NUTRITION PHYSIOLOGY; PSYCHOMETRICS; VITAMINS;

EID: 34249112819     PISSN: None     EISSN: 14752891     Source Type: Journal    
DOI: 10.1186/1475-2891-6-10     Document Type: Article

References (22)

1. Dietary factors and Alzheimer's disease. JA Luchsinger R Mayeux, Lancet Neurol 2004 3 579 87 10.1016/S1474-4422(04)00878-6 15380154
2. Randomised controlled trial of homocysteine lowering vitamin treatment in elderly people with vascular disease. DJ Stott G MacIntosh GD Lowe A Rumley AD McMahon P Langhorne R Campbell Tail DStJ O'Reilly EG Spilg JB MacDonald PW MacFarlane RGJ Westendorp, Am J Clin Nutr 2005 82 1320 6 16332666
3. A controlled trial of homocysteine lowering and cognitive performance. JA McMahon TJ Green CM Skeaff RG Knight JI Mann SM Williams, N Engl J Med 2006 354 2764 72 10.1056/NEJMoa054025 16807413
4. Effect of oral vitamin B12 with or without folic acid on cognitive function in older people with mild vitamin B12 deficiency: a randomised, placebo-controlled trial. SJ Eussen LC de Groot LW Joosten RJ Bloo R Clarke PM Ueland J Schneede HJ Blom WH Hoefnagels WA van Staveren, Am J Clin Nutr 2006 84 361 70 16895884
5. MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20536 high-risk individuals: a randomised placebo-controlled trial. Heart Protection Study Collaborative Group, Lancet 2002 360 23 33 10.1016/S0140- 6736(02)09328-5 12114037
6. Age Related Eye Disease Study Group. Impact of antioxidants, zinc and copper on cognition in the elderly: a randomized, controlled trial. K Yaffe TE Clemons WL McBee AS Lindblad, Neurology 2004 63 1705 07 15534261
7. Vitamin E and donepezil for the treatment of mild cognitive impairment. RC Petersen RG Thomas M Grundman D Bennett R Doody S Ferris D Galasko S Jin J Kaye A Levey E Pfeiffer M Sano CH van Dyck LJ Thai for the Alzheimer's Disease Cooperative Study Group, N Engl J Med 2005 352 2379 88 10.1056/NEJMoa050151 15829527
8. Anti-oxidant vitamins and mental performance of the elderly. A Smith R Clark D Nutt J Haller S Hayward K Perry, Hum Psychopharmacol Clin Exp 1999 14 459 71 10.1002/(SICI)1099-1077(199910)14:7<459::AID-HUP128〉3.0.CO;2-0
9. Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial. J Durga MPJ van Boxtel EG Schouten FJ Kok J Jolles MB Katan P Verhoef, Lancet 2007 369 208 16 10.1016/S0140-6736(07)60109-3 17240287
10. The influence of multivitamins on cognitive function and mood in the elderly. SM Cockle J Haller S Kimber RA Dawe I Hindmarch, Aging and Mental Health 2000 4 339 353
11. Cognitive performance in relation to vitamin status in healthy elderly German women - the effect of 6-month multivitamin supplementation. M Wolters M Hickstein A Flinterman U Tewes A Hahan, Prev Med 2005 41 253 9 10.1016/j.ypmed.2004.11.007 15917019
12. Effect of an enriched drink on cognitive function in frail elderly persons. W Wouters-Wesseling LW Wagenaar M Rozendaal JB Deijen LC de Groot JG Bindels WA van Staveren, J Gerontol A Biol Sci Med Sci 2005 60 265 70 15814873
13. Effect of vitamin and trace-element supplementation on cognitive function in elderly subjects. RK Chandra, Nutrition 2001 17 709 12 10.1016/S0899- 9007(01)00610-4 11527656
14. Retraction. MM Meguid, Nutrition 2005 21 286 10.1016/j.nut.2004.12.002 15793927
15. Effect of multivitamin and multimineral supplements on morbidity from infections in older people (MAVIS trial): pragmatic, randomised, double blind, placebo controlled trial. A Avenell MK Campbell JA Cook PC Hannaford MM Kilonzo G McNeill AC Milne CR Ramsay DG Seymour AI Stephen LD Vale, BMJ 2005 331 324 329 16081445 10.1136/bmj.331.7512.324
16. st March 2007)
17. D Wechsler, Memory scale London: Harcourt, Brace & Company 3 1998
18. O Spreen E Strauss, A compendium of neuropsychological tests: administration, norms and commentary Oxford: Oxford University Press 2 1998
19. Predictors of micronutrient status in men and women over 75 years old living in the community. G McNeill J Vyvyan H Peace L McKie G Seymour J Hendry I MacPherson, Br J Nutr 2002 88 555 61 10.1079/BJN2002706 12425736
20. Supplement use is associated with health status and health-related behaviours in the 1946 British birth cohort. SA McNaughton GD Mishra AA Paul CJ Prynne ME Wadsworth, J Nutr 2005 135 1782 9 15987865
21. MD Lezak, Neuropsychological assessment New York, Oxford University Press 3 1995 211 218
22. Normative data stratified by age and education for two measures of verbal fluency. TN Tombaugh J Kozak L Rees, Arch Clin Neuropsychol 1999 14 167 77 10.1016/S0887-6177(97)00095-4 14590600