Effect of protopanaxatriol saponin on spermatogenic stem cell survival in busulfan-treated male mice

Reproductive Medicine and Biology

Volumn 6, Issue 2, 2007, Pages 99-108

  Ji, Minyoung ^a   Minami, Naojiro ^a   Yamada, Masayasu ^a   Imai, Hiroshi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Busulfan; Epididymis; Ginsenoside; Spermatogenesis; Testes

Indexed keywords

BUSULFAN; PROTOPANAXADIOL; SAPONIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; EPIDIDYMIS TAIL; GERM CELL; MALE; MALE INFERTILITY; MOUSE; NONHUMAN; OLIGOSPERMIA; PRIORITY JOURNAL; SEMINIFEROUS TUBULE; SPERMATOGENESIS; SPERMATOGONIUM; SPERMATOZOON; STEM CELL; TESTIS INJURY; TESTIS WEIGHT;

EID: 34249107960     PISSN: 14455781     EISSN: 14470578     Source Type: Journal    
DOI: 10.1111/j.1447-0578.2007.00172.x     Document Type: Article

References (50)

1. Galton DA. Myleran in choronic myeloid leukemia - results of treatment. Lancet 1953; 31: 208-213
2. Galton DA, Till M, Wiltshaw E. Busulfan (1,4-butanediolmethanesulfonate, Myleran): Summary of clinical results. Ann New York Acad Sci 1958; 68: 967-973.
3. Wilkinson JF, Turner RL. Chemotheraphy of choronic myeloid leukemia, with special reference to Myleran. Prog Hematol 1959; 2: 225-238.
4. Bucci LR, Meistrich ML. Effect of busulfan on murine spermatogenesis: cytotoxicity, sterility, sperm abnormalities, and dominant lethal mutations. Mutat Res 1987; 176: 259-268.
5. Meistrich ML, van Beek MEAB. Spermatogonial stem cell. In: Desjardins C, Ewing LL, eds. Cell and Molecular Biology of the Testis. NY Oxford: Oxford University Press, 1993; 266-295.
6. Dym M. Spermatogonial stem cells on the testis. Proc Natl Acad Sci USA 1994; 91: 11287-11289.
7. De Rooij DG. Stem cell in testis. Int J Exp Pathol 1998; 79: 67-80.
8. Yamamoto K, Hitotsumachi S, Kikuchi Y. Occurrence of premature chromosome condensation in mouse spermatogonia treated with busulfan. Cytogen Cell Genet 1986; 43: 127-131.
9. Molineux G, Testa NG, Massa G, Schofield R. An analysis of haemopoietic and microenvironmental populations of mouse bone marrow after treatment with busulphan. Biomed Pharmacother 1986; 40: 215-220.
10. Brinster RL, Zimmermann JW. Spermatogenesis following male germ cell transplantation. Proc Nat Acad Sci USA 1994; 91: 11298-11302.
11. Ogawa T, Arechaga JM, Avarbock MR, Brinster RL. Transplantation of testis germinal cells into mouse seminiferous tubules. Int J Dev Biol 1997; 41: 111-122.
12. Dobrinski I, Avabock MR, Brinster RL. Transplantation of germ cells from rabbits and dogs into mouse testes. Biol Reprod 1999; 61: 1331-1339.
13. Nagano M, Avarbock MR, Brinster RL. Pattern and kinetics of mouse donor spermatogonial stem cell colonization in recipient testes. Biol Reprod 1999; 60: 1429-1436.
14. Hu SY. A contribution of our knowledge of ginseng. Am J Chin Med 1977; 5: 1-23.
15. Ashok K. Chemopreventive action of ginseng on DMBA-induced papillomagenesis in the skin of mice. Proc 6th Int Ginseng Symp 1993; 66-68.
16. Huang KC. The Pharmacology Chinese Herbs. Boca Raton: CRC Press, 1999.
17. Attele AS, Wu JA, Yuan CS. Ginseng pharmacology: Multiple constituents and multiple actions. Biochem Pharmacol 1999; 58: 1685-1693.
18. Gillis CN. Panax Ginseng Pharmacology: A nitric oxide link?. Biochem Pharmacol 1999; 54: 1-8.
19. Lee YJ, Chung E, Lee KY, Lee YH, Huh B, Lee SK. Ginsenoside-Rg1, one of the major active molecules from Panax ginseng, is a functional ligand of glucocorticoid receptor. Mol Cell Endocrinol 1997; 133: 135-140.
20. Yun TK, Yun YS, Han IW. Anticarcinogenic effect of long-term oral administration of red ginseng on newborn mice exposed to various chemical carcinogens. Cancer Det Prev 1983; 6: 515-525.
21. Ota T, Fujikawa-Yamamoto K, Zong ZP et al. Plant-glycoside modulation of cell surface related to control of differentiation in cultured B16 melanoma cells. Cancer Res 1987; 47: 3863-3867.
22. Mochizuki M et al. Inhibitory effect of tumor metastasis in mice by saponins, ginsenoside-Rb2, 20(R) and 20(S)-ginsenoside-Rg3, of red ginseng. Biol Pharm Bull 1995; 18: 1197-1202.
23. Wakabayashi C, Murakami K, Hasegawa H, Murata J, Saiki I. An intestinal bacterial metabolite of ginseng protopanaxadiol saponins has the ability to induce apoptosis in tumor cells. Biochem Biophys Res Comms 1998; 46: 725-730.
24. Saito H, Tsuchiya M, Naka S, Takagi K. Effects of Panax Ginseng root on conditioned avoidance response in rats. Jpn J Pharmacol 1977; 27: 509-516.
25. Benishin CG, Lee R, Wang LC, Liu HJ. Effects of ginsenoside Rb1 on central cholinergic metabolism. Pharmacology 1991; 42: 223-229.
26. Scott GI, Colligan PB, Ren BH, Ren J. Ginsenosides Rb1 and Re decrease cardiac con-traction in adult rat ventricular myocytes: Role of nitric oxide. Br J Pharmacol 2001; 134: 1159-1165.
27. Lee CS, Gibson NW. Nucleotide preferences for DNA inter strand cross-linking induced by the cyclopropylpyrroloindol analogue U-77, 779. Biochemistry 1993; 32: 2592-2600.
28. Chan RY, Chen WF, Dong A, Guo D, Wong MS. Estrogen-like activity of ginsenoside Rg1 derived from Panax notoginseng. J Clin Endocrinol Met 2002; 87: 3691-3695.
29. Cho JY, Kim AR, Yoo ES, Baik KU, Park MH. Ginsenosides from Panax ginseng differentially regulate lymphocyte proliferation. Planta Med 2002; 68: 497-500.
30. Lian X, Zhang J. Effect of ginsenoside Rb1 on repeated stress-in duced sexual deficiency resin male mice. Yao Xue Xue Bao 1998; 33: 184-187.
31. Kim DH, Moon YS, Jung JS et al. Effects of ginseng saponin administered intraperitoneally on the hypothalamo-pituitary renal axis in mice. Neuroscience Lett 2003; 343: 62-66.
32. Park YC, Lee CH, Kang HS, Kim KW, Chung HT, Kim HD. Ginsenoside-Rh1 and Rh2 inhibit the induction of nitric oxide synthesis in murine peritoneal macrophages. Biochem Mol Biol Int 1996; 40: 751-757.
33. Marret C, Durand P. Culture of porcine spermatogonia: Effects of purification of the germ cells, extracellular matrix and fetal calf serum on their survival and multiplication. Reprod Nut Dev 2000; 40: 305-319.
34. Van der Wee K, Jonhson EW, Dirami G, Dym M, Hofmann MC. Immunomagnetic isolation and long-term culture of mouse type a spermatogonia. J Androl 2001; 22: 696-704.
35. Meistrich ML, Goldstein LS, Wyrobek AJ. Long-term infertility and dominant lethal mutations in male mice treated with adriamycin. Mutat Res 1985; 152: 53-65.
36. Jackson H, Fox BW, Craig AW. Antifertility substances and their assessment in the male rodent. J Reprod Fertil 1961; 2: 447-465.
37. Van Keulen CJG, de Rooij DG. Spermatogenetic clones developing from repopulating stem cells surviving a high dose of an alkylating agent. Cell Tissue Kinet 1975; 8: 543-551.
38. Jiang FX. Behavior of spermatogonia following recovery from busulfan treatment in the rat. Anat Embryol 1998; 198: 53-61.
39. Kim YS, Kang KS, Kim SI. Effect of ginseng components on immunotoxicity of cyclophosphamide. Korean J Ginseng Sci 1991; 15: 13-20.
40. Rhee YH, Ahn JH, Choe J, Kang KW, Joe C. Inhibition of mutagenesis and transformation by root extracts of Panax ginseng in vitro. Planta Med 1991; 57: 125-128.
41. Hwang SJ, Cha JY, Park SG et al. Diol- and triol-type ginseng saponins potentiate the apoptosis of NIH3T3 cells exposed to methyl methanesulfonate. Toxicol Appl Pharmacol 2002; 181: 192-202.
42. Forsti A, Hemminski K. Unique properties of cisplatin in reactions with nucleophiles. IARC Scientific Publication 1986; 78: 101-110.
43. Povirk LF, Shunker DE. DNA damage and mutagenesis induced by nitrogen mustards. Mutat Res 1994; 318: 205-226.
44. Kang J, K et al. Ginseng intestinal metabolite-I (GIM-I) reduces doxorubicin toxicity in the mouse testis. Reprod Toxicol 2002; 16: 291-298.
45. Kim W, Hwang S, Lee H, Song H, Kim S. Panax ginseng protects the testes against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced testicular damage in guineapigs. BJU Int 1999; 83: 842-849.
46. Fahim MS, Fahim Z, Harman JM, Clevenger TE, Mullins W, Hafez ES. Effect of Panax ginseng on testosterone level and prostate in male rat. Arch Androl 1982; 8: 261-263.
47. Salvati G et al. Effects of Panax ginseng C.A. Meyer saponins on male fertility. Panminerva Med 1996; 38: 249-254.
48. Chen JC, Chen LD, Tsauer W, Tsai CC, Chen BC, Chen YJ. Effects of ginsenoside Rb2 and Rc on inferior human sperm motility in vitro. Am J Chin Med 2001; 29: 155-160.
49. Tsai SC, Chiao YC, Lu CC, Wang PS. Stimulation of the secretion of luteinizing hormone by ginsenoside Rb1 in male rats. Chinese J Physiol 2003; 46: 1-17.
50. Zhang H, Zhou Q, Li X et al. Ginsenoside Re promotes human sperm capacitation through nitric oxide-dependent pathway. Mol Reprod Dev 2007; 74: 497-501.