Nasal administration of an angiotensin antagonist in the rat model: Effect of bioadhesive formulations on the distribution of drugs to the systemic and central nervous systems

International Journal of Pharmaceutics

Volumn 338, Issue 1-2, 2007, Pages 94-103

  Charlton, S T ^a   Davis, S S ^a,b   Illum, L ^c  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b Cosmas Damian Ltd ^*  (United Kingdom)

^c IDentity   (United Kingdom)

Author keywords

Bioadhesive formulations; Chitosan; Nasal administration; Olfactory region; Pectin

Indexed keywords

CHITOSAN; PECTIN; SAPRISARTAN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; BRAIN REGION; BRAIN TISSUE; CENTRAL NERVOUS SYSTEM FUNCTION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG STRUCTURE; DRUG TRANSPORT; MALE; NONHUMAN; NOSE CAVITY; PRIORITY JOURNAL; RAT;

ABSORPTION; ADHESIVENESS; ADMINISTRATION, INTRANASAL; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BENZOFURANS; BRAIN; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; MALE; NASAL MUCOSA; PECTINS; RATS; RATS, WISTAR;

EID: 34249074260     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.01.047     Document Type: Article

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