Smoking-dependent and haplotype-specific effects of endothelial nitric oxide synthase gene polymorphisms on angiographically assessed coronary artery disease in Caucasian- and African-Brazilians

Atherosclerosis

Volumn 193, Issue 1, 2007, Pages 135-141

  Rios, Domingos L S ^a,b   D'Onofrio, Lorenza O ^b,c   Souza, Joares K ^b,c   Queiroz, Amália M ^b   Raduy Maron, Luciana ^b,c   Silva Neto, Naila ^b   Carvalho, Heitor G ^d   Santos Filho, Ademar ^d   Galvão Castro, Bernardo ^b,c  

^a UNIVERSIDADE ESTADUAL DO SUDOESTE DA BAHIA   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c Dental School of Fundação Bahiana para O Desenvolvimento Das Ciências   (Brazil)

^d HOSPITAL SANTA IZABEL   (Brazil)

Author keywords

African Brazilians; Coronary artery disease; Endothelial nitric oxide synthase; Polymorphisms

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE;

ADULT; ALLELE; ANGIOCARDIOGRAPHY; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DEMOGRAPHY; FEMALE; GENE FREQUENCY; GENE MUTATION; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; SMOKING HABIT;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; ALLELES; BRAZIL; CASE-CONTROL STUDIES; CORONARY ANGIOGRAPHY; CORONARY ARTERIOSCLEROSIS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; HAPLOTYPES; HETEROZYGOTE; HOMOZYGOTE; HUMANS; INTRONS; MALE; MIDDLE AGED; NITRIC OXIDE SYNTHASE TYPE III; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; REPETITIVE SEQUENCES, NUCLEIC ACID; SMOKING;

EID: 34249066453     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2006.05.041     Document Type: Article

References (28)

1. Peyser P.A. Genetic epidemiology of coronary artery disease. Epidemiol Rev 19 1 (1997) 80-90
2. Napoli C., and Ignarro L.J. Nitric oxide and atherosclerosis. Nitric Oxide 5 2 (2001) 88-97
3. Hingorani A.D. Polymorphisms in endothelial nitric oxide synthase and atherogenesis: John French Lecture 2000. Atherosclerosis 154 3 (2001) 521-527
4. Wang X.L., and Wang J. Endothelial nitric oxide synthase gene sequence variations and vascular disease. Mol Genet Metab 70 4 (2000) 241-251
5. Casas J.P., Bautista L.E., Humphries S.E., and Hingorani A.D. Endothelial nitric oxide synthase genotype and ischemic heart disease: metaanalysis of 26 studies involving 23,028 subjects. Circulation 109 (2004) 1359-1365
6. Miyamoto Y., Saito Y., Nakayama M., et al. RPA1 represses the eNOS gene with T-786C mutations: a molecular mechanism for predisposition to coronary spastic angina. Circulation 100 suppl. I (1999) I-754
7. Alvarez R., Gonzalez P., Batalla A., et al. Association between the NOS3 (-786T/C) and the ACE (I/D) DNA genotypes and early coronary artery disease. Nitric Oxide 5 4 (2001) 343-348
8. Rios D.L., Callegari-Jacques S.M., and Hutz M.H. Endothelial nitric oxide synthase and fractalkine chemokine receptor polymorphisms on angiographically assessed coronary atherosclerosis. Clin Chim Acta 362 1-2 (2005) 138-146
9. Wang X.L., Sim A.S., Badenhop R.F., McCredie R.M., and Wilcken D.E. A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene. Nat Med 2 1 (1996) 41-45
10. Leeson C.P., Hingorani A.D., Mullen M.J., et al. Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function. Circ Res 90 11 (2002) 1153-1158
11. Hingorani A.D., Liang C.F., Fatibene J., et al. A common variant of the endothelial nitric oxide synthase (Glu298 → Asp) is a major risk factor for coronary artery disease in the UK. Circulation 100 14 (1999) 1515-1520
12. Colombo M.G., Andreassi M.G., Paradossi U., et al. Evidence for association of a common variant of the endothelial nitric oxide synthase gene (Glu298 → Asp polymorphism) to the presence, extent, and severity of coronary artery disease. Heart 87 6 (2002) 525-528
13. Gardemann A., Lohre J., Cayci S., et al. The T allele of the missense Glu(298)Asp endothelial nitric oxide synthase gene polymorphism is associated with coronary heart disease in younger individuals with high atherosclerotic risk profile. Atherosclerosis 160 1 (2002) 167-175
14. Granath B., Taylor R.R., van Bockxmeer F.M., and Mamotte C.D. Lack of evidence for association between endothelial nitric oxide synthase gene polymorphisms and coronary artery disease in the Australian Caucasian population. J Cardiovasc Risk 8 4 (2001) 235-241
15. Sandrim VC, Coelho EB, Nobre F, et al. Susceptible and protective eNOS haplotypes in hypertensive black and white subjects. Atherosclerosis [available online in 2005 September 14].
16. Talmud P.J., and Humphries S.E. Genetic polymorphisms, lipoproteins and coronary artery disease risk. Curr Opin Lipidol 12 4 (2001) 405-409
17. Poredos P., Orehek M., and Tratnik E. Smoking is associated with dose-related increase of intima-media thickness and endothelial dysfunction. Angiology 50 3 (1999) 201-208
18. Wang X.L., Sim A.S., Wang M.X., et al. Genotype dependent and cigarette specific effects on endothelial nitric oxide synthase gene expression and enzyme activity. FEBS Lett 471 1 (2000) 45-50
19. Tavares L.H.D. Historia da Bahia. 10th ed. (2001), UNESP/EDUFBA Publishers, São Paulo/Salvador, Brazil 542 pp.
20. Azevedo E.S. Subgroup studies of black admixture within a mixed population of Bahia, Brazil. Ann Hum Genet 44 Pt 1 (1980) 55-60
21. Friedewald W.T., Levy R.I., and Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18 6 (1972) 499-502
22. Schneider S., Roessli D., and Excoffier L. Arlequin Ver. 2000: a software for populations genetics analysis (2000), Genetics and Biometry Laboratory, University of Geneva, Switzerland
23. Lewontin RC. On measures of gametic disequilibrium. Genetics 1988;1,20(3):849-52.
24. Abramson J.H., and Gahlinger P.M. Computer programs for epidemiologists: PEPI, Version 4.0 (2001), Sagebrush Press, Salt Lake City
25. Marroni A.S., Metzger I.F., Souza-Costa D.C., et al. Consistent interethnic differences in the distribution of clinically relevant endothelial nitric oxide synthase genetic polymorphisms. Nitric Oxide 12 (2005) 177-182
26. Hooper W.C., Lally C., Austin H., et al. The relationship between polymorphisms in the endothelial cell nitric oxide synthase gene and the platelet GPIIIa gene with myocardial infarction and venous thromboembolism in African Americans. Chest 116 4 (1999) 880-886
27. Wang J., Dudley D., and Wang X.L. Haplotype-specific effects on endothelial NO synthase promoter efficiency: modifiable by cigarette smoking. Arterioscler Thromb Vasc Biol 22 5 (2002) e1-e4
28. Sarkar R., Gelabert H.A., Mohiuddin K.R., Thakor D.K., and Santibanez-Gallerani A.S. Effect of cigarette smoke on endothelial regeneration in vivo and nitric oxide levels. J Surg Res 82 1 (1999) 43-47