Clues or miscues? How to make the right interpretation and correctly diagnose long-QT syndrome

Circulation

Volumn 115, Issue 20, 2007, Pages 2595-2598

  Vetter, Victoria L ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

Arrhythmia; Death, sudden; Editorials; Electrocardiography; Long QT syndrome; Syncope

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT;

ANAMNESIS; DEFIBRILLATOR; DIAGNOSTIC ACCURACY; EDITORIAL; ELECTROCARDIOGRAM; FAMILY HISTORY; GENE MUTATION; GENETIC PROCEDURES; HUMAN; LONG QT SYNDROME; PRIORITY JOURNAL; QT INTERVAL; QT PROLONGATION; SUDDEN DEATH; T WAVE;

CHILD; DIAGNOSTIC ERRORS; ELECTROCARDIOGRAPHY; GENETIC SCREENING; HUMANS; LONG QT SYNDROME; MEDICAL HISTORY TAKING;

EID: 34249054456     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.107.700195     Document Type: Editorial

References (21)

1. Schwartz PJ, Periti M, Malliani A. The long Q-T syndrome. Am Heart J. 1975;89:378-390.
2. Garson A Jr, Dick M II, Fournier A, Gillette PC, Hamilton R, Kugler JD, van Hair GF III, Vetter V, Vick GW III. The long QT syndrome in children: an international study of 287 patients. Circulation. 1993;87: 1866-1872.
3. Schwartz PJ. The congenital long QT syndromes from genotype to phenotype: clinical implications. J Intern Med. 2006;259:39-47.
4. Jervell A, Lange-Nielsen F. Congenital deaf-mutism, functional heart diseases, with prolongation of the QT interval and sudden death. Am Heart J. 1957;54:59-68.
5. Romano C, Gemme G, Pongiglione R. Aritmie cardiache rare delle¢eta pediatrica. Clin Pediatr (Bologna). 1963;45:656-683.
6. Ward O. A new familial cardiac syndrome in children. J Ir Med Assoc. 1964;54:103-106.
7. Moss AJ, Schwartz PJ, Crampton RS, Tzivoni D, Locati EH, MacCluer J, Hall WJ, Weitkamp L, Vincent GM, Garson A Jr. The long QT syndrome: prospective longitudinal study of 328 families. Circulation. 1991;84:1136-1144.
8. Moss AJ, Schwartz PJ, Crompton RS, Locati E, Carleen E. The long QT syndrome: a prospective international study. Circulation. 1985;71:17-21.
9. Moss AJ, Schwartz PJ. 25th anniversary of the International Long-QT Syndrome Registry: an ongoing quest to uncover the secrets of long-QT syndrome. Circulation. 2005;111:1199-1201.
10. Priori SG, Schwartz PJ, Napolitano C, Bloise R, Ronchetti E, Grillo M, Vicentini A, Spazzolini C, Nastoli J, Bottelli G, Folli R, Cappelletti D. Risk stratification in the long-QT syndrome. N Engl J Med. 2003;348: 1866-1874.
11. Vincent GM, Timothy KW, Leppert M, Keating M. The spectrum of symptoms and QT intervals in carriers of the gene for the long QT syndrome. N Engl J Med. 1992;327:846-852.
12. Splawski I, Shen J, Timothy K, Lehmann MH, Priori SG, Robinson JL, Moss AJ, Schwartz PJ, Towbin JA, Vincent GM, Keating MT. Spectrum of mutations in long-QT syndrome genes. Circulation. 2000;102: 1178-1185.
13. Taggart NW, Haglund CM, Tester DJ, Ackerman MJ. Diagnostic miscues in congenital long-QT syndrome. Circulation. 2007;115:2613-2620.
14. Schwartz PJ, Moss AJ, Vincent GM, Crampton RS. Diagnostic criteria for the long QT syndrome: an update. Circulation. 1993;88:782-784.
15. Priori SG, Napolitano C, Schwartz PJ. Low penetrance in the long-QT syndrome: clinical impact. Circulation. 1999;99:529-533.
16. Viskin S, Rosovski U, Sands AJ, Chen E, Kistler PM, Kalman JM, Rodriguez CL, Iturralde TP, Cruz FF, Centurion OA, Fujiki A, Maury P, Chen X, Krahn AD, Roithinger F, Zhang L, Vincent GM, Zeltser D. Inaccurate electrocardiographic interpretation of long QT: the majority of physicians cannot recognize a long QT when they see one. Heart Rhythm. 2005;2:569-574.
17. Goldenberg I, Moss AJ, Zareba W. QT interval: how to measure it and what is "normal." J Cardiovasc Electrophysiol. 2006;17:333-336.
18. Hobbs JB, Peterson DR, Moss AJ, McNitt S, Zareba W, Goldenberg I, Qi M, Robinson JL, Sauer AJ, Ackerman MJ, Benhorin J, Kaufman ES, Locati EH, Napolitano C, Priori SG, Towbin JA, Vincent GM, Zhang L. Risk of aborted cardiac arrest or sudden cardiac death during adolescence in the long-QT syndrome. JAMA. 2006;296:1249-1254.
19. Goldenberg I, Mathew J, Moss AJ, McNitt S, Peterson DR, Zareba W, Benhorin J, Zhang L, Vincent GM, Andrews ML, Robinson JL, Morray B. Corrected QT variability in serial electrocardiograms in long QT syndrome: the importance of the maximum corrected QT for risk stratification. J Am Coll Cardiol. 2006;48:1047-1052.
20. Moss AJ, Zareba W, Benhorin J, Locati EH, Hall WJ, Robinson JL, Schwartz PJ, Towbin JA, Vincent GM, Lehmann MH, Keating MT. ECG-T wave patterns in genetically distinct forms of the hereditary long QT syndrome. Circulation. 1995;92:2929-2934.
21. Schwartz PJ, Priori SG, Spazzolini C, Moss AJ, Vincent GM, Napolitano C, Denjoy I, Guicheney P, Breithardt G, Keating MT, Towbin JA, Beggs AH, Brink P, Wilde AA, Toivonen L, Zareba W, Robinson JL, Timothy KW, Corfield V, Wattanasirichaigoon D, Corbett C, Haverkamp W, Schulze-Bahr E, Lehmann MH, Schwartz K, Coumel P, Bloise R. Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias. Circulation. 2001;103:89-95.